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SJ Baumgart
SJ Baumgart
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Year
Recent advances in prostate cancer treatment and drug discovery
E Nevedomskaya, SJ Baumgart, B Haendler
International journal of molecular sciences 19 (5), 1359, 2018
2622018
The novel ATR inhibitor BAY 1895344 is efficacious as monotherapy and combined with DNA damage–inducing or repair–compromising therapies in preclinical cancer models
AM Wengner, G Siemeister, U Lücking, J Lefranc, L Wortmann, P Lienau, ...
Molecular cancer therapeutics 19 (1), 26-38, 2020
1552020
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness
V Kari, WY Mansour, SK Raul, SJ Baumgart, A Mund, M Grade, H Sirma, ...
EMBO reports 17 (11), 1609-1623, 2016
1102016
BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire
Z Najafova, R Tirado-Magallanes, M Subramaniam, T Hossan, G Schmidt, ...
Nucleic acids research 45 (1), 127-141, 2017
1072017
Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models
T Sugawara, SJ Baumgart, E Nevedomskaya, K Reichert, H Steuber, ...
International Journal of Cancer 145 (5), 1382-1394, 2019
652019
Krüppel-like transcription factor KLF10 suppresses TGFβ-induced epithelial-to-mesenchymal transition via a negative feedback mechanism
VK Mishra, M Subramaniam, V Kari, KS Pitel, SJ Baumgart, RM Naylor, ...
Cancer research 77 (9), 2387-2400, 2017
572017
RNF40 regulates gene expression in an epigenetic context-dependent manner
W Xie, S Nagarajan, SJ Baumgart, RL Kosinsky, Z Najafova, V Kari, ...
Genome biology 18, 1-22, 2017
462017
Exploiting epigenetic alterations in prostate cancer
SJ Baumgart, B Haendler
International journal of molecular sciences 18 (5), 1017, 2017
442017
Histone chaperone SSRP1 is essential for Wnt signaling pathway activity during osteoblast differentiation
T Hossan, S Nagarajan, SJ Baumgart, W Xie, RT Magallanes, ...
Stem Cells 34 (5), 1369-1376, 2016
372016
Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation
SJ Baumgart, E Nevedomskaya, R Lesche, R Newman, D Mumberg, ...
Molecular oncology 14 (9), 2022-2039, 2020
332020
CHD1 regulates cell fate determination by activation of differentiation-induced genes
SJ Baumgart, Z Najafova, T Hossan, W Xie, S Nagarajan, V Kari, N Ditzel, ...
Nucleic acids research 45 (13), 7722-7735, 2017
302017
Dysregulated transcriptional control in prostate cancer
SJ Baumgart, E Nevedomskaya, B Haendler
International Journal of Molecular Sciences 20 (12), 2883, 2019
252019
The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models
C Lemos, VK Schulze, SJ Baumgart, E Nevedomskaya, T Heinrich, ...
Cellular Oncology 44, 581-594, 2021
172021
MACA: marker-based automatic cell-type annotation for single-cell expression data
Y Xu, SJ Baumgart, CM Stegmann, S Hayat
Bioinformatics 38 (6), 1756-1760, 2022
142022
Darolutamide potentiates the antitumor efficacy of a PSMA-targeted thorium-227 conjugate by a dual mode of action in prostate cancer models
S Hammer, A Schlicker, S Zitzmann-Kolbe, S Baumgart, UB Hagemann, ...
Clinical Cancer Research 27 (15), 4367-4378, 2021
142021
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness
V Kari, WY Mansour, SK Raul, SJ Baumgart, A Mund, M Grade, H Sirma, ...
EMBO reports 19 (10), e46783, 2018
132018
Single-nucleus RNA sequencing in ischemic cardiomyopathy reveals common transcriptional profile underlying end-stage heart failure
B Simonson, M Chaffin, MC Hill, O Atwa, Y Guedira, H Bhasin, AW Hall, ...
Cell reports 42 (2), 2023
112023
Fibrotic signaling in cardiac fibroblasts and vascular smooth muscle cells: the dual roles of fibrosis in HFpEF and CAD
JC Bachmann, SJ Baumgart, AK Uryga, MH Bosteen, G Borghetti, ...
Cells 11 (10), 1657, 2022
92022
CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo
SJ Oh-Hohenhorst, D Tilki, AK Ahlers, A Suling, O Hahn, P Tennstedt, ...
Cancer Gene Therapy 29 (1), 49-61, 2022
72022
Comparative proteomic and transcriptomic analysis of the impact of androgen stimulation and darolutamide inhibition
E Nevedomskaya, T Sugawara, SJ Baumgart, R Lesche, H Hahne, ...
Cancers 15 (1), 2, 2022
22022
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