Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an … M Bonafè, M Barbieri, F Marchegiani, F Olivieri, E Ragno, C Giampieri, ... The Journal of Clinical Endocrinology & Metabolism 88 (7), 3299-3304, 2003 | 380 | 2003 |
A gender–dependent genetic predisposition to produce high levels of IL‐6 is detrimental for longevity M Bonafè, F Olivieri, L Cavallone, S Giovagnetti, F Marchegiani, ... European journal of immunology 31 (8), 2357-2361, 2001 | 365 | 2001 |
Do men and women follow different trajectories to reach extreme longevity? C Franceschi, L Motta, S Valensin, R Rapisarda, A Franzone, M Berardelli, ... Aging Clinical and Experimental Research 12, 77-84, 2000 | 357 | 2000 |
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of … C Franceschi, F Olivieri, F Marchegiani, M Cardelli, L Cavallone, M Capri, ... Mechanisms of ageing and development 126 (2), 351-361, 2005 | 254 | 2005 |
Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10− 1082 promoter SNP and its interaction with TNF-α− 308 promoter SNP D Lio, L Scola, A Crivello, G Colonna-Romano, G Candore, M Bonafè, ... Journal of medical genetics 40 (4), 296-299, 2003 | 222 | 2003 |
Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease A Santoro, V Balbi, E Balducci, C Pirazzini, F Rosini, F Tavano, A Achilli, ... PloS one 5 (8), e12037, 2010 | 143 | 2010 |
The G/C915 polymorphism of transforming growth factor β1 is associated with human longevity: a study in Italian centenarians G Carrieri, E Marzi, F Olivieri, F Marchegiani, L Cavallone, M Cardelli, ... Aging cell 3 (6), 443-448, 2004 | 137 | 2004 |
The− 174 C/G locus affects in vitro/in vivo IL-6 production during aging F Olivieri, M Bonafè, L Cavallone, S Giovagnetti, F Marchegiani, ... Experimental gerontology 37 (2-3), 309-314, 2002 | 117 | 2002 |
Effect of etanercept on insulin sensitivity in nine patients with psoriasis M Marra, A Campanati, R Testa, C Sirolla, AR Bonfigli, C Franceschi, ... International journal of immunopathology and pharmacology 20 (4), 731-736, 2007 | 103 | 2007 |
Leukocyte telomere shortening in elderly Type2DM patients with previous myocardial infarction F Olivieri, M Lorenzi, R Antonicelli, R Testa, C Sirolla, M Cardelli, ... Atherosclerosis 206 (2), 588-593, 2009 | 99 | 2009 |
Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis IM Rea, PP McKeown, D McMaster, IS Young, C Patterson, MJ Savage, ... Experimental gerontology 39 (4), 629-635, 2004 | 96 | 2004 |
Genes, ageing and longevity in humans: problems, advantages and perspectives S Salvioli, F Olivieri, F Marchegiani, M Cardelli, A Santoro, E Bellavista, ... Free Radical Research 40 (12), 1303-1323, 2006 | 95 | 2006 |
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians M Bonafè, F Marchegiani, M Cardelli, F Olivieri, L Cavallone, ... European Journal of Human Genetics 10 (5), 292-296, 2002 | 94 | 2002 |
The interleukin-6− 174 G> C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients R Antonicelli, F Olivieri, M Bonafè, L Cavallone, L Spazzafumo, ... International journal of cardiology 103 (3), 266-271, 2005 | 93 | 2005 |
Interleukin-6–174 G> C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients R Testa, F Olivieri, AR Bonfigli, C Sirolla, M Boemi, F Marchegiani, ... Diabetes research and clinical practice 71 (3), 299-305, 2006 | 83 | 2006 |
Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics M Capri, S Salvioli, D Monti, C Caruso, G Candore, S Vasto, F Olivieri, ... Experimental Gerontology 43 (2), 53-60, 2008 | 81 | 2008 |
Inflammation, chronic obstructive pulmonary disease and aging M Provinciali, M Cardelli, F Marchegiani Current opinion in pulmonary medicine 17, S3-S10, 2011 | 77 | 2011 |
Tumor necrosis factor-alpha gene− 308G> A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers R Antonicelli, F Olivieri, L Cavallone, L Spazzafumo, M Bonafè, ... Coronary artery disease 16 (8), 489-493, 2005 | 74 | 2005 |
An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease F Lescai, AM Chiamenti, A Codemo, C Pirazzini, G D'Agostino, C Ruaro, ... Journal of Alzheimer's Disease 24 (2), 235-245, 2011 | 69 | 2011 |
P53 codon 72 polymorphism and longevity: additional data on centenarians from continental Italy and Sardinia M Bonafè, F Olivieri, D Mari, G Baggio, R Mattace, M Berardelli, P Sansoni, ... American Journal of Human Genetics 65 (6), 1782, 1999 | 68 | 1999 |