Mechanisms of aquaporin-facilitated cancer invasion and metastasis ML De Ieso, AJ Yool Frontiers in chemistry 6, 135, 2018 | 99 | 2018 |
Bumetanide derivatives AqB007 and AqB011 selectively block the aquaporin-1 ion channel conductance and slow cancer cell migration M Kourghi, JV Pei, ML De Ieso, G Flynn, AJ Yool Molecular pharmacology 89 (1), 133-140, 2016 | 70 | 2016 |
The vital role for nitric oxide in intraocular pressure homeostasis E Reina-Torres, ML De Ieso, LR Pasquale, M Madekurozwa, ... Progress in retinal and eye research 83, 100922, 2021 | 67 | 2021 |
Differential inhibition of water and ion channel activities of mammalian aquaporin-1 by two structurally related bacopaside compounds derived from the medicinal plant bacopa … JV Pei, M Kourghi, ML De Ieso, EM Campbell, HS Dorward, ... Molecular pharmacology 90 (4), 496-507, 2016 | 61 | 2016 |
Effect of compound kushen injection, a natural compound mixture, and its identified chemical components on migration and invasion of colon, brain, and breast cancer cell lines S Nourmohammadi, TN Aung, J Cui, JV Pei, ML De Ieso, Y Harata-Lee, ... Frontiers in oncology 9, 314, 2019 | 53 | 2019 |
Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow O Yarishkin, TTT Phuong, JM Baumann, ML De Ieso, F Vazquez‐Chona, ... The Journal of physiology 599 (2), 571-592, 2021 | 45 | 2021 |
An accurate and cost-effective alternative method for measuring cell migration with the circular wound closure assay ML De Ieso, JV Pei Bioscience reports 38 (5), BSR20180698, 2018 | 44 | 2018 |
Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life M Kourghi, JV Pei, ML De Ieso, S Nourmohammadi, PH Chow, AJ Yool Clinical and Experimental Pharmacology and Physiology 45 (4), 401-409, 2018 | 43 | 2018 |
Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration ML De Ieso, JV Pei, S Nourmohammadi, E Smith, PH Chow, M Kourghi, ... Scientific reports 9 (1), 12635, 2019 | 40 | 2019 |
Identification of loop D domain amino acids in the human Aquaporin-1 channel involved in activation of the ionic conductance and inhibition by AqB011 M Kourghi, ML De Ieso, S Nourmohammadi, JV Pei, AJ Yool Frontiers in chemistry 6, 142, 2018 | 26 | 2018 |
Consensus recommendation for mouse models of ocular hypertension to study aqueous humor outflow and its mechanisms CM McDowell, K Kizhatil, MH Elliott, DR Overby, ... Investigative ophthalmology & visual science 63 (2), 12-12, 2022 | 23 | 2022 |
Development of a photoswitchable lithium-sensitive probe to analyze nonselective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, G Sylvia, M Kourghi, S Nourmohammadi, ... Molecular Pharmacology 95 (5), 573-583, 2019 | 21 | 2019 |
Physiologic consequences of caveolin-1 ablation in conventional outflow endothelia ML De Ieso, JM Gurley, ME McClellan, X Gu, I Navarro, G Li, ... Investigative ophthalmology & visual science 61 (11), 32-32, 2020 | 15 | 2020 |
Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease EN Enyong, JM Gurley, ML De Ieso, WD Stamer, MH Elliott Progress in retinal and eye research 91, 101094, 2022 | 11 | 2022 |
Drug discovery and therapeutic targets for pharmacological modulators of aquaporin channels JV Pei, JL Burton, M Kourghi, ML De Ieso, AJ Yool Aquaporins in Health and Disease: New Molecular Targets For Drug Discovery …, 2016 | 11 | 2016 |
A role of Caveolae in trabecular meshwork Mechanosensing and contractile tone ML De Ieso, M Kuhn, P Bernatchez, MH Elliott, WD Stamer Frontiers in cell and developmental biology 10, 855097, 2022 | 6 | 2022 |
Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology H Li, M Kuhn, RA Kelly, A Singh, KK Palanivel, I Salama, ML De Ieso, ... American Journal of Physiology-Cell Physiology 326 (2), C513-C528, 2024 | 2 | 2024 |
Lithium'Hot-spots': Real-time Analysis of non-selective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, GM Sylvia, M Kourghi, S Nourmohammadi, ... Molecular Pharmacology, 2019 | 2 | 2019 |
Development and testing of a metabolic chamber for effluent collection during whole eye perfusions ML De Ieso, R Kelly, P Mzyk, WD Stamer Experimental Eye Research 236, 109652, 2023 | 1 | 2023 |
Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells HM Schmitt, KM Hake, KM Perkumas, BM Lê, MF Suarez, ML De Ieso, ... Human Molecular Genetics 32 (21), 3053-3062, 2023 | 1 | 2023 |