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Elana Thieme
Elana Thieme
Verified email at uw.edu
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Cited by
Year
Pharmacologic Targeting of Mcl-1 Induces Mitochondrial Dysfunction and Apoptosis in B-Cell Lymphoma Cells in a TP53- and BAX-Dependent Manner
T Liu, V Lam, E Thieme, D Sun, X Wang, F Xu, L Wang, OV Danilova, ...
Clinical Cancer Research 27 (17), 4910-4922, 2021
272021
Dual BTK/SYK inhibition with CG-806 (luxeptinib) disrupts B-cell receptor and Bcl-2 signaling networks in mantle cell lymphoma
E Thieme, T Liu, N Bruss, C Roleder, V Lam, X Wang, T Nechiporuk, ...
Cell death & disease 13 (3), 246, 2022
162022
CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma
E Thieme, N Bruss, D Sun, EC Dominguez, D Coleman, T Liu, C Roleder, ...
Molecular Cancer 22 (1), 64, 2023
82023
Generation of a humanized afucosylated BAFF-R antibody with broad activity against human B-cell malignancies
Z Dong, JY Song, E Thieme, A Anderson, E Oh, WA Cheng, BZ Kuang, ...
Blood Advances 7 (6), 918-932, 2023
42023
Pharmacologic targeting MCL1 with AZD5991 induces apoptosis and mitochondrial dysfunction in non-Hodgkin lymphoma (NHL) cells
T Liu, F Xu, E Thieme, V Lam, G Fan, L Nikolaenko, SE Kurtz, JW Tyner, ...
Blood 136, 33, 2020
42020
Transcriptional reprogramming of super-enhancer associated oncogenes following inhibition of cyclin-dependent kinase-9 (CDK9) in aggressive non-Hodgkin lymphoma (NHL)
E Thieme, D Sun, GG Sharma, N Bruss, T Liu, DJ Coleman, Z Xia, ...
Blood 138, 3493, 2021
22021
Pharmacologic Inhibition of B Cell-Receptor-Associated Kinases with CG-806 Induces Apoptosis and Metabolic Reprogramming in Aggressive Non-Hodgkin Lymphoma (NHL) Models
E Thieme, V Lam, N Bruss, F Xu, SE Kurtz, JW Tyner, A Danilov, T Liu
Blood 136, 29, 2020
22020
Targeting Sumoylation with Subasumstat (TAK-981), a Selective Inhibitor of SUMO-Activating Enzyme (SAE), Induces Mitochondrial Dysfunction in Preclinical Models of Non-Hodgkin …
T Liu, V Lam, E Thieme, O Danilova, N Bruss, L Alinari, JW Tyner, ...
Blood 140 (Supplement 1), 6016-6017, 2022
2022
Abstract A02: Probing the roles of SUMOylation in B-cell lymphoma cells by using a selective SUMO inhibitor subasumstat (TAK-981)
T Liu, V Lam, D Sun, E Thieme, T Nechiporuk, D Bottomly, OV Danilova, ...
Blood Cancer Discovery 3 (5_Supplement), A02-A02, 2022
2022
Abstract A06: Strategies to circumvent resistance to cyclin-dependent kinase-9 inhibition (CDK9i) in non-Hodgkin lymphoma (NHL)
E Thieme, D Sun, N Bruss, G Sharma, T Liu, D Coleman, T Nechiporuk, ...
Blood Cancer Discovery 3 (5_Supplement), A06-A06, 2022
2022
Pharmacologic targeting Mcl-1 with AZD5991 induces apoptosis, suppresses mitochondrial respiration and overcomes ibrutinib resistance in non-Hodgkin lymphoma cells
T Liu, V Lam, E Thieme, X Wang, F Xu, S Kurtz, J Tyner, OV Danilova, ...
Cancer Research 81 (13_Supplement), 938-938, 2021
2021
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