pH-triggered, macromolecule-sized poration of lipid bilayers by synthetically evolved peptides G Wiedman, SY Kim, E Zapata-Mercado, WC Wimley, K Hristova Journal of the American Chemical Society 139 (2), 937-945, 2017 | 78 | 2017 |
Applications and evolution of melittin, the quintessential membrane active peptide S Guha, RP Ferrie, J Ghimire, CR Ventura, E Wu, L Sun, SY Kim, ... Biochemical pharmacology 193, 114769, 2021 | 77 | 2021 |
Potent macromolecule-sized poration of lipid bilayers by the macrolittins, a synthetically evolved family of pore-forming peptides S Li, SY Kim, AE Pittman, GM King, WC Wimley, K Hristova Journal of the American Chemical Society 140 (20), 6441-6447, 2018 | 55 | 2018 |
Mechanism of action of peptides that cause the pH-triggered macromolecular poration of lipid bilayers SY Kim, AE Pittman, E Zapata-Mercado, GM King, WC Wimley, K Hristova Journal of the American Chemical Society 141 (16), 6706-6718, 2019 | 37 | 2019 |
Enhancing the membrane activity of Piscidin 1 through peptide metallation and the presence of oxidized lipid species: Implications for the unification of host defense … SD Paredes, S Kim, MT Rooney, AI Greenwood, K Hristova, ML Cotten Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (7), 183236, 2020 | 19 | 2020 |
Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot G Kelly, JJ Milligan, EM Mastria, S Kim, SR Zelenetz, J Dobbins, LY Cai, ... Journal of Controlled Release 343, 267-276, 2022 | 18 | 2022 |
pH-triggered pore-forming peptides with strong composition-dependent membrane selectivity SY Kim, AN Bondar, WC Wimley, K Hristova Biophysical journal 120 (4), 618-630, 2021 | 11 | 2021 |
Genetically engineered nanoparticles of asymmetric triblock polypeptide with a platinum (IV) cargo outperforms a platinum (II) analog and free drug in a murine cancer model S Saha, S Banskota, J Liu, N Zakharov, M Dzuricky, X Li, P Fan, ... Nano letters 22 (14), 5898-5908, 2022 | 4 | 2022 |
Pore-Forming Peptides and Uses Thereof WC Wimley, G Wiedman, K Hristova, SY Kim US Patent US 2019 / 0211063 A1, 2019 | | 2019 |