Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6086 | 2018 |
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1191 | 2015 |
The promise of retinoids to fight against cancer L Altucci, H Gronemeyer Nature Reviews Cancer 1 (3), 181-193, 2001 | 982 | 2001 |
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway A Insinga, S Monestiroli, S Ronzoni, V Gelmetti, F Marchesi, A Viale, ... Nature medicine 11 (1), 71-76, 2005 | 671 | 2005 |
RAR and RXR modulation in cancer and metabolic disease L Altucci, MD Leibowitz, KM Ogilvie, AR de Lera, H Gronemeyer Nature reviews Drug discovery 6 (10), 793-810, 2007 | 634 | 2007 |
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells A Nebbioso, N Clarke, E Voltz, E Germain, C Ambrosino, P Bontempo, ... Nature medicine 11 (1), 77-84, 2005 | 614 | 2005 |
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ... Cell 167 (5), 1145-1149, 2016 | 546 | 2016 |
Cancer epigenetics: Moving forward A Nebbioso, FP Tambaro, C Dell’Aversana, L Altucci PLoS genetics 14 (6), e1007362, 2018 | 516 | 2018 |
Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells E Habibi, AB Brinkman, J Arand, LI Kroeze, HHD Kerstens, F Matarese, ... Cell stem cell 13 (3), 360-369, 2013 | 509 | 2013 |
17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G (1)-arrested human breast … L Altucci, R Addeo, L Cicatiello, S Dauvois, MG Parker, M Truss, M Beato, ... Oncogene 12 (11), 2315-2324, 1996 | 477 | 1996 |
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL L Altucci, A Rossin, W Raffelsberger, A Reitmair, C Chomienne, ... Nature medicine 7 (6), 680-686, 2001 | 443 | 2001 |
BLUEPRINT to decode the epigenetic signature written in blood D Adams, L Altucci, SE Antonarakis, J Ballesteros, S Beck, A Bird, C Bock, ... Nature biotechnology 30 (3), 224-226, 2012 | 388 | 2012 |
Sirtuin functions and modulation: from chemistry to the clinic V Carafa, D Rotili, M Forgione, F Cuomo, E Serretiello, GS Hailu, E Jarho, ... Clinical epigenetics 8, 1-21, 2016 | 380 | 2016 |
PML-RARα/RXR alters the epigenetic landscape in acute promyelocytic leukemia JHA Martens, AB Brinkman, F Simmer, KJ Francoijs, A Nebbioso, ... Cancer cell 17 (2), 173-185, 2010 | 347 | 2010 |
Design of selective nuclear receptor modulators: RAR and RXR as a case study AR de Lera, W Bourguet, L Altucci, H Gronemeyer Nature reviews Drug discovery 6 (10), 811-820, 2007 | 326 | 2007 |
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect E Lara, A Mai, V Calvanese, L Altucci, P Lopez-Nieva, ... Oncogene 28 (6), 781-791, 2009 | 308 | 2009 |
Trials with ‘epigenetic’drugs: an update A Nebbioso, V Carafa, R Benedetti, L Altucci Molecular oncology 6 (6), 657-682, 2012 | 290 | 2012 |
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment C Colussi, C Mozzetta, A Gurtner, B Illi, J Rosati, S Straino, G Ragone, ... Proceedings of the National Academy of Sciences 105 (49), 19183-19187, 2008 | 279 | 2008 |
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead A Mai, L Altucci The international journal of biochemistry & cell biology 41 (1), 199-213, 2009 | 265 | 2009 |
The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin V Quagliariello, M De Laurentiis, D Rea, A Barbieri, MG Monti, A Carbone, ... Cardiovascular diabetology 20, 1-20, 2021 | 264 | 2021 |