Lucia Altucci, MD, PhD
Lucia Altucci, MD, PhD
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Cited by
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ...
Cell Death & Differentiation 22 (1), 58-73, 2015
The promise of retinoids to fight against cancer
L Altucci, H Gronemeyer
Nature Reviews Cancer 1 (3), 181-193, 2001
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
A Insinga, S Monestiroli, S Ronzoni, V Gelmetti, F Marchesi, A Viale, ...
Nature medicine 11 (1), 71-76, 2005
RAR and RXR modulation in cancer and metabolic disease
L Altucci, MD Leibowitz, KM Ogilvie, AR de Lera, H Gronemeyer
Nature reviews Drug discovery 6 (10), 793-810, 2007
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
A Nebbioso, N Clarke, E Voltz, E Germain, C Ambrosino, P Bontempo, ...
Nature medicine 11 (1), 77-84, 2005
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ...
Cell 167 (5), 1145-1149, 2016
Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells
E Habibi, AB Brinkman, J Arand, LI Kroeze, HHD Kerstens, F Matarese, ...
Cell stem cell 13 (3), 360-369, 2013
Cancer epigenetics: Moving forward
A Nebbioso, FP Tambaro, C Dell’Aversana, L Altucci
PLoS genetics 14 (6), e1007362, 2018
17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G (1)-arrested human breastá…
L Altucci, R Addeo, L Cicatiello, S Dauvois, MG Parker, M Truss, M Beato, ...
Oncogene 12 (11), 2315-2324, 1996
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
L Altucci, A Rossin, W Raffelsberger, A Reitmair, C Chomienne, ...
Nature medicine 7 (6), 680-686, 2001
BLUEPRINT to decode the epigenetic signature written in blood
D Adams, L Altucci, SE Antonarakis, J Ballesteros, S Beck, A Bird, C Bock, ...
Nature biotechnology 30 (3), 224-226, 2012
Sirtuin functions and modulation: from chemistry to the clinic
V Carafa, D Rotili, M Forgione, F Cuomo, E Serretiello, GS Hailu, E Jarho, ...
Clinical epigenetics 8, 1-21, 2016
PML-RARα/RXR alters the epigenetic landscape in acute promyelocytic leukemia
JHA Martens, AB Brinkman, F Simmer, KJ Francoijs, A Nebbioso, ...
Cancer cell 17 (2), 173-185, 2010
Design of selective nuclear receptor modulators: RAR and RXR as a case study
AR de Lera, W Bourguet, L Altucci, H Gronemeyer
Nature reviews Drug discovery 6 (10), 811-820, 2007
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect
E Lara, A Mai, V Calvanese, L Altucci, P Lopez-Nieva, ...
Oncogene 28 (6), 781-791, 2009
Trials with ‘epigenetic’drugs: an update
A Nebbioso, V Carafa, R Benedetti, L Altucci
Molecular oncology 6 (6), 657-682, 2012
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment
C Colussi, C Mozzetta, A Gurtner, B Illi, J Rosati, S Straino, G Ragone, ...
Proceedings of the National Academy of Sciences 105 (49), 19183-19187, 2008
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead
A Mai, L Altucci
The international journal of biochemistry & cell biology 41 (1), 199-213, 2009
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl) pyrrolyl hydroxyamides
A Mai, S Massa, R Pezzi, S Simeoni, D Rotili, A Nebbioso, ...
Journal of medicinal chemistry 48 (9), 3344-3353, 2005
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