Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 710 | 2018 |
GM-CSF induces inflammatory macrophages by regulating glycolysis and lipid metabolism YR Na, GJ Gu, D Jung, YW Kim, J Na, JS Woo, JY Cho, H Youn, SH Seok The Journal of Immunology 197 (10), 4101-4109, 2016 | 91 | 2016 |
Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer H Lu, N Villafane, T Dogruluk, CL Grzeskowiak, K Kong, YH Tsang, ... Cancer research 77 (13), 3502-3512, 2017 | 41 | 2017 |
Proteomic analysis reveals distinct metabolic differences between granulocyte-macrophage colony stimulating factor (GM-CSF) and macrophage colony stimulating factor (M-CSF … YR Na, JH Hong, MY Lee, JH Jung, D Jung, YW Kim, D Son, M Choi, ... Molecular & Cellular Proteomics 14 (10), 2722-2732, 2015 | 29 | 2015 |
A method to delineate de novo missense variants across pathways prioritizes genes linked to autism A Koire, P Katsonis, YW Kim, C Buchovecky, SJ Wilson, O Lichtarge Science Translational Medicine 13 (594), 2021 | 22 | 2021 |
Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease YW Kim, I Al‐Ramahi, A Koire, SJ Wilson, DM Konecki, S Mota, ... Alzheimer's & Dementia, 2020 | 17 | 2020 |
A general calculus of fitness landscapes finds genes under selection in cancers TK Hsu, J Asmussen, A Koire, BK Choi, MA Gadhikar, E Huh, CH Lin, ... Genome Research 32 (5), 916-929, 2022 | 9 | 2022 |
Codon-level co-occurrences of germline variants and somatic mutations in cancer are rare but often lead to incorrect variant annotation and underestimated impact prediction A Koire, YW Kim, J Wang, P Katsonis, H Jin, O Lichtarge PloS one 12 (3), e0174766, 2017 | 3 | 2017 |
Evolutionary Action of de novo missense variants across pathways prioritizes genes linked to autism and predicts patient phenotypic severity A Koire, C Buchovecky, P Katsonis, YW Kim, SJ Wilson, O Lichtarge bioRxiv, 158329, 2017 | | 2017 |