| Ezetimibe lipid-lowering trial on prevention of atherosclerotic cardiovascular disease in 75 or older (ewtopia 75) A randomized, controlled trial Y Ouchi, J Sasaki, H Arai, K Yokote, K Harada, Y Katayama, T Urabe, ... Circulation 140 (12), 992-1003, 2019 | 176 | 2019 |
| Crystal structure of NADH-cytochrome b5 reductase from pig liver at 2.4. ANG. Resolution H Nishida, K Inaka, M Yamanaka, S Kaida, K Kobayashi, K Miki Biochemistry 34 (9), 2763-2767, 1995 | 111 | 1995 |
| The Closed Structure of an Archaeal DNA Ligase from Pyrococcus furiosus H Nishida, S Kiyonari, Y Ishino, K Morikawa Journal of molecular biology 360 (5), 956-967, 2006 | 67 | 2006 |
| Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex K Mayanagi, S Kiyonari, H Nishida, M Saito, D Kohda, Y Ishino, T Shirai, ... Proceedings of the National Academy of Sciences 108 (5), 1845-1849, 2011 | 61 | 2011 |
| Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex H Nishida, K Mayanagi, S Kiyonari, Y Sato, T Oyama, Y Ishino, ... Proceedings of the National Academy of Sciences 106 (49), 20693-20698, 2009 | 52 | 2009 |
| Identification of a novel binding motif in Pyrococcus furiosus DNA ligase for the functional interaction with proliferating cell nuclear antigen S Kiyonari, K Takayama, H Nishida, Y Ishino Journal of biological chemistry 281 (38), 28023-28032, 2006 | 51 | 2006 |
| Electrostatic properties deduced from refined structures of NADH‐cytochrome b5 reductase and the other flavin‐dependent reductases: Pyridine nucleotide … H Nishida, K Miki Proteins: Structure, Function, and Bioinformatics 26 (1), 32-41, 1996 | 39 | 1996 |
| Specific arrangement of three amino acid residues for flavin‐binding barrel structures in NADH‐cytochrome b 5 reductase and the other flavin‐dependent reductases H Nishida, K Inaka, K Miki FEBS letters 361 (1), 97-100, 1995 | 35 | 1995 |
| Self-oriented immobilization of DNA polymerase tagged by titanium-binding peptide motif H Nishida, T Kajisa, Y Miyazawa, Y Tabuse, T Yoda, H Takeyama, ... Langmuir 31 (2), 732-740, 2015 | 34 | 2015 |
| Effects of Flavin-Binding Motif Amino Acid Mutations in the NADH-Cytochrome b5 Reductase Catalytic Domain on Protein Stability and Catalysis S Kimura, H Nishida, T Iyanagi The Journal of Biochemistry 130 (4), 481-490, 2001 | 34 | 2001 |
| Crystallization and preliminary X-ray diffraction studies of photolyase (photoreactivating enzyme) from the cyanobacterium Anacystis nidulans K Miki, T Tamada, H Nishida, K Inaka, A Yasui, PE de Ruiter, APM Eker Journal of molecular biology 233 (1), 167-169, 1993 | 26 | 1993 |
| Size-selective harvesting of extracellular vesicles for strategic analyses towards tumor diagnoses C Manri, T Yokoi, H Nishida Applied Biochemistry and Biotechnology 182, 609-623, 2017 | 16 | 2017 |
| Structure‐Based Mutational Study of an Archaeal DNA Ligase towards Improvement of Ligation Activity M Tanabe, S Ishino, M Yohda, K Morikawa, Y Ishino, H Nishida ChemBioChem 13 (17), 2575-2582, 2012 | 15 | 2012 |
| Overexpression, purification and crystallization of an archaeal DNA ligase from Pyrococcus furiosus H Nishida, D Tsuchiya, Y Ishino, K Morikawa Acta Crystallographica Section F: Structural Biology and Crystallization …, 2005 | 14 | 2005 |
| Identification of the critical region in replication factor C from Pyrococcus furiosus for the stable complex formation with proliferating cell nuclear antigen and DNA H Nishida, S Ishino, T Miyata, K Morikawa, Y Ishino Genes & genetic systems 80 (2), 83-93, 2005 | 12 | 2005 |
| From structure-function analyses to protein engineering for practical applications of DNA ligase M Tanabe, Y Ishino, H Nishida Archaea 2015, 2015 | 11 | 2015 |
| Transmission electron microscope T Kohashi, T Ohshima, T Matsumoto, H Nishida US Patent 7,755,046, 2010 | 9 | 2010 |
| Mutations of Asp540 and the domain-connecting residues synergistically enhance Pyrococcus furiosus DNA ligase activity M Tanabe, S Ishino, Y Ishino, H Nishida FEBS letters 588 (2), 230-235, 2014 | 8 | 2014 |
| Stoichiometric complex formation by proliferating cell nuclear antigen (PCNA) and its interacting protein: Purification and crystallization of the DNA polymerase and PCNA … H Nishida, S Matsumiya, D Tsuchiya, Y Ishino, K Morikawa Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 6 | 2006 |
| DNA ligase mutants H Nishida, Y Ishino, K Morikawa US Patent 7,927,853, 2011 | 5 | 2011 |
