Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity RG Gaudet, A Sintsova, CM Buckwalter, N Leung, A Cochrane, J Li, ... Science 348 (6240), 1251-1255, 2015 | 159 | 2015 |
TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection A Gall, RG Gaudet, SD Gray-Owen, NR Salama MBio 8 (4), 10.1128/mbio. 01168-17, 2017 | 123 | 2017 |
Antibodies in infectious diseases: polyclonals, monoclonals and niche biotechnology JD Berry, RG Gaudet New biotechnology 28 (5), 489-501, 2011 | 101 | 2011 |
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling M Abdel-Nour, LAM Carneiro, J Downey, J Tsalikis, A Outlioua, D Prescott, ... Science 365 (6448), eaaw4144, 2019 | 100 | 2019 |
Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression RJ Malott, BO Keller, RG Gaudet, SE McCaw, CCL Lai, ... Proceedings of the National Academy of Sciences 110 (25), 10234-10239, 2013 | 85 | 2013 |
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ... MBio 9 (4), 10.1128/mbio. 01581-18, 2018 | 63 | 2018 |
Innate recognition of intracellular bacterial growth is driven by the TIFA-dependent cytosolic surveillance pathway RG Gaudet, CX Guo, R Molinaro, H Kottwitz, JR Rohde, AS Dangeard, ... Cell reports 19 (7), 1418-1430, 2017 | 60 | 2017 |
A human apolipoprotein L with detergent-like activity kills intracellular pathogens RG Gaudet, S Zhu, A Halder, BH Kim, CJ Bradfield, S Huang, D Xu, ... Science 373 (6552), eabf8113, 2021 | 58 | 2021 |
Heptose sounds the alarm: innate sensing of a bacterial sugar stimulates immunity RG Gaudet, SD Gray-Owen PLoS pathogens 12 (9), e1005807, 2016 | 28 | 2016 |
Evolution of cell‐autonomous effector mechanisms in macrophages versus non‐immune cells RG Gaudet, CJ Bradfield, JD MacMicking Myeloid Cells in Health and Disease: A Synthesis, 615-635, 2017 | 22 | 2017 |
High-throughput screening identifies genes required for Candida albicans induction of macrophage pyroptosis. mBio 9: e01581-18 TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ... | 13 | 2018 |
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection D Xu, W Jiang, L Wu, RG Gaudet, ES Park, M Su, SK Cheppali, ... Nature 619 (7971), 819-827, 2023 | 10 | 2023 |
Molecular characterization of the cervical and systemic B-cell repertoire: Unique, yet overlapping, immune compartments of an HIV-1 resistant individual RG Gaudet, F Breden, F Plummer, JD Berry MAbs 3 (2), 181-191, 2011 | 8 | 2011 |
Methods of modulating immune system responses S Gray-Owen, R Gaudet, R Malott US Patent 10,238,738, 2019 | 4 | 2019 |
TIFA-Mediated Innate Immune Recognition of the Bacterial Metabolite HBP and its Role in Host Defense RG Gaudet University of Toronto (Canada), 2016 | 1 | 2016 |
Human XIRP1 is a macrophage podosome protein utilized by Listeria for actin-based motility R Urbano, ES Park, K Tretina, A Tunaru, RG Gaudet, X Hu, DZ Wang, ... bioRxiv, 2022.08. 28.505595, 2022 | | 2022 |
Modifying Red Cell Computerized Order Entry for Patients with Red Blood Cell Antibodies: Attempting to Reduce Blood Bank Utilization Wastage and Transfusion Delays G Wool, RG Gaudet, A Dye, MF O'Connor, A Treml TRANSFUSION 55, 215A-215A, 2015 | | 2015 |
The Isolation of gp41 Specific Monoclonal Antibodies from the Cervical IgA Repertoire of Highly Exposed Persistently Seronegative (HEPS) Commercial Sex Workers from Nairobi … RG Gaudet | | 2010 |
Patent 2963724 Summary S GRAY-OWEN, R GAUDET, R MALOTT | | |
Molecular characterization of the cervical and systemic B-cell repertoire RG Gaudet, F Breden, F Plummer, JD Berry | | |