Synthetic RNA Polymerase III Promoters Facilitate High-Efficiency CRISPR–Cas9-Mediated Genome Editing in Yarrowia lipolytica CM Schwartz, MS Hussain, M Blenner, I Wheeldon ACS synthetic biology 5 (4), 356-359, 2016 | 346 | 2016 |
Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica C Schwartz, M Shabbir-Hussain, K Frogue, M Blenner, I Wheeldon ACS synthetic biology 6 (3), 402-409, 2017 | 188 | 2017 |
Genome and metabolic engineering in non-conventional yeasts: current advances and applications AK Löbs, C Schwartz, I Wheeldon Synthetic and systems biotechnology 2 (3), 198-207, 2017 | 139 | 2017 |
CRISPRi repression of nonhomologous end‐joining for enhanced genome engineering via homologous recombination in Yarrowia lipolytica C Schwartz, K Frogue, A Ramesh, J Misa, I Wheeldon Biotechnology and bioengineering 114 (12), 2896-2906, 2017 | 126 | 2017 |
CRISPR–Cas9-enabled genetic disruptions for understanding ethanol and ethyl acetate biosynthesis in Kluyveromyces marxianus AK Löbs, R Engel, C Schwartz, A Flores, I Wheeldon Biotechnology for biofuels 10, 1-14, 2017 | 102 | 2017 |
Stress-tolerant non-conventional microbes enable next-generation chemical biosynthesis S Thorwall, C Schwartz, JW Chartron, I Wheeldon Nature chemical biology 16 (2), 113-121, 2020 | 96 | 2020 |
Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica C Schwartz, JF Cheng, R Evans, CA Schwartz, JM Wagner, S Anglin, ... Metabolic engineering 55, 102-110, 2019 | 92 | 2019 |
Host and Pathway Engineering for Enhanced Lycopene Biosynthesis in Yarrowia lipolytica C Schwartz, K Frogue, J Misa, I Wheeldon Frontiers in Microbiology 8, 2233, 2017 | 89 | 2017 |
Multiplexed CRISPR Activation of Cryptic Sugar Metabolism Enables Yarrowia Lipolytica Growth on Cellobiose C Schwartz, N Curtis, AK Löbs, I Wheeldon Biotechnology journal 13 (9), 1700584, 2018 | 86 | 2018 |
Highly Multiplexed CRISPRi Repression of Respiratory Functions Enhances Mitochondrial Localized Ethyl Acetate Biosynthesis in Kluyveromyces marxianus AK Löbs, C Schwartz, S Thorwall, I Wheeldon ACS Synthetic Biology 7 (11), 2647-2655, 2018 | 57 | 2018 |
Genome-wide functional screens enable the prediction of high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica D Baisya, A Ramesh, C Schwartz, S Lonardi, I Wheeldon Nature communications 13 (1), 922, 2022 | 28 | 2022 |
CRISPR-Cas9-Mediated Genome Editing and Transcriptional Control in Yarrowia lipolytica C Schwartz, I Wheeldon Synthetic Biology: Methods and Protocols, 327-345, 2018 | 28 | 2018 |
Controlled intracellular trafficking alleviates an expression bottleneck in S. cerevisiae ester biosynthesis J Zhu, C Schwartz, I Wheeldon Metabolic engineering communications 8, e00085, 2019 | 13 | 2019 |
Genome‐wide CRISPR‐Cas9 screen reveals a persistent null‐hyphal phenotype that maintains high carotenoid production in Yarrowia lipolytica B Lupish, J Hall, C Schwartz, A Ramesh, C Morrison, I Wheeldon Biotechnology and Bioengineering 119 (12), 3623-3631, 2022 | 7 | 2022 |
CRISPR Interference and Activation to Modulate Transcription in Yarrowia lipolytica J Misa, C Schwartz Yarrowia lipolytica: Methods and Protocols, 95-109, 2021 | 4 | 2021 |
System and method for determining an offensive, defensive, and cumulative efficiency of a sports team RA Bowman, G Klayman, C Schwartz US Patent 8,121,712, 2012 | 4 | 2012 |
Design of hybrid RNA polymerase III promoters for efficient CRISPR-Cas9 function J Misa, C Schwartz, I Wheeldon Bio-protocol 8 (6), e2779-e2779, 2018 | 3 | 2018 |
acCRISPR: an activity-correction method for improving the accuracy of CRISPR screens A Ramesh, V Trivedi, S Lee, A Tafrishi, C Schwartz, A Mohseni, M Li, ... Communications biology 6 (1), 617, 2023 | 2 | 2023 |
Commentary systems and methods C Schwartz US Patent 10,188,943, 2019 | 2 | 2019 |
Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast C Schwartz, JF Cheng, R Evans | | 2019 |