Christine Fillmore Brainson
Christine Fillmore Brainson
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Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
PB Gupta, CM Fillmore, G Jiang, SD Shapira, K Tao, C Kuperwasser, ...
Cell 146 (4), 633-644, 2011
Non-small-cell lung cancers: a heterogeneous set of diseases
Z Chen, CM Fillmore, PS Hammerman, CF Kim, KK Wong
Nature Reviews Cancer 14 (8), 535-546, 2014
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
CM Fillmore, C Kuperwasser
Breast cancer research 10 (2), 1-13, 2008
Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression
C Xu, CM Fillmore, S Koyama, H Wu, Y Zhao, Z Chen, GS Herter-Sprie, ...
Cancer cell 25 (5), 590-604, 2014
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling
CM Fillmore, PB Gupta, JA Rudnick, S Caballero, PJ Keller, ES Lander, ...
Proceedings of the National Academy of Sciences 107 (50), 21737-21742, 2010
EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors
CM Fillmore, C Xu, PT Desai, JM Berry, SP Rowbotham, YJ Lin, H Zhang, ...
Nature 520 (7546), 239-242, 2015
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation
MS Isakoff, CG Sansam, P Tamayo, A Subramanian, JA Evans, ...
Proceedings of the National Academy of Sciences 102 (49), 17745-17750, 2005
Tumor‐propagating cells and Y ap/T az activity contribute to lung tumor progression and metastasis
AN Lau, SJ Curtis, CM Fillmore, SP Rowbotham, M Mohseni, DE Wagner, ...
The EMBO journal 33 (5), 468-481, 2014
Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?
C Fillmore, C Kuperwasser
Breast cancer research 9, 1-3, 2007
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
SJ Zacharek, CM Fillmore, AN Lau, DW Gludish, A Chou, JWK Ho, ...
Cell stem cell 9 (3), 272-281, 2011
Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung CancerAn Oncogenic Role for EZH2 in Lung Cancer
H Zhang, J Qi, JM Reyes, L Li, PK Rao, F Li, CY Lin, JA Perry, MA Lawlor, ...
Cancer discovery 6 (9), 1006-1021, 2016
Lung stem and progenitor cells in tissue homeostasis and disease
KT Leeman, CM Fillmore, CF Kim
Current topics in developmental biology 107, 207-233, 2014
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2
H Zhang, C Fillmore Brainson, S Koyama, AJ Redig, T Chen, S Li, ...
Nature communications 8 (1), 14922, 2017
Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis
KW Sinkevicius, C Kriegel, KJ Bellaria, J Lee, AN Lau, KT Leeman, ...
Proceedings of the National Academy of Sciences 111 (28), 10299-10304, 2014
Nuclear glycogenolysis modulates histone acetylation in human non-small cell lung cancers
RC Sun, VV Dukhande, Z Zhou, LEA Young, S Emanuelle, CF Brainson, ...
Cell metabolism 30 (5), 903-916. e7, 2019
The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells
Z Castaņo, CM Fillmore, CF Kim, SS McAllister
Seminars in cancer biology 22 (5-6), 462-470, 2012
H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression
SP Rowbotham, F Li, AFM Dost, SM Louie, BP Marsh, P Pessina, ...
Nature Communications 9 (1), 4559, 2018
The epithelial sodium channel is a modifier of the long-term nonprogressive phenotype associated with F508del CFTR mutations
PB Agrawal, R Wang, HL Li, K Schmitz-Abe, C Simone-Roach, J Chen, ...
American journal of respiratory cell and molecular biology 57 (6), 711-720, 2017
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation
RC Sun, LEA Young, RC Bruntz, KH Markussen, Z Zhou, LR Conroy, ...
Cell metabolism 33 (7), 1404-1417. e9, 2021
BRG1 loss predisposes lung cancers to replicative stress and ATR dependency
M Gupta, CP Concepcion, CG Fahey, H Keshishian, A Bhutkar, ...
Cancer research 80 (18), 3841-3854, 2020
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