Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells PB Gupta, CM Fillmore, G Jiang, SD Shapira, K Tao, C Kuperwasser, ... Cell 146 (4), 633-644, 2011 | 1528 | 2011 |
Non-small-cell lung cancers: a heterogeneous set of diseases Z Chen, CM Fillmore, PS Hammerman, CF Kim, KK Wong Nature Reviews Cancer 14 (8), 535-546, 2014 | 1447 | 2014 |
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy CM Fillmore, C Kuperwasser Breast cancer research 10 (2), 1-13, 2008 | 1268 | 2008 |
Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression C Xu, CM Fillmore, S Koyama, H Wu, Y Zhao, Z Chen, GS Herter-Sprie, ... Cancer cell 25 (5), 590-604, 2014 | 349 | 2014 |
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling CM Fillmore, PB Gupta, JA Rudnick, S Caballero, PJ Keller, ES Lander, ... Proceedings of the National Academy of Sciences 107 (50), 21737-21742, 2010 | 320 | 2010 |
EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors CM Fillmore, C Xu, PT Desai, JM Berry, SP Rowbotham, YJ Lin, H Zhang, ... Nature 520 (7546), 239-242, 2015 | 243 | 2015 |
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation MS Isakoff, CG Sansam, P Tamayo, A Subramanian, JA Evans, ... Proceedings of the National Academy of Sciences 102 (49), 17745-17750, 2005 | 227 | 2005 |
Tumor‐propagating cells and Y ap/T az activity contribute to lung tumor progression and metastasis AN Lau, SJ Curtis, CM Fillmore, SP Rowbotham, M Mohseni, DE Wagner, ... The EMBO journal 33 (5), 468-481, 2014 | 215 | 2014 |
Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man? C Fillmore, C Kuperwasser Breast cancer research 9, 1-3, 2007 | 202 | 2007 |
Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci SJ Zacharek, CM Fillmore, AN Lau, DW Gludish, A Chou, JWK Ho, ... Cell stem cell 9 (3), 272-281, 2011 | 143 | 2011 |
Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung CancerAn Oncogenic Role for EZH2 in Lung Cancer H Zhang, J Qi, JM Reyes, L Li, PK Rao, F Li, CY Lin, JA Perry, MA Lawlor, ... Cancer discovery 6 (9), 1006-1021, 2016 | 99 | 2016 |
Lung stem and progenitor cells in tissue homeostasis and disease KT Leeman, CM Fillmore, CF Kim Current topics in developmental biology 107, 207-233, 2014 | 88 | 2014 |
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2 H Zhang, C Fillmore Brainson, S Koyama, AJ Redig, T Chen, S Li, ... Nature communications 8 (1), 14922, 2017 | 85 | 2017 |
Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis KW Sinkevicius, C Kriegel, KJ Bellaria, J Lee, AN Lau, KT Leeman, ... Proceedings of the National Academy of Sciences 111 (28), 10299-10304, 2014 | 83 | 2014 |
Nuclear glycogenolysis modulates histone acetylation in human non-small cell lung cancers RC Sun, VV Dukhande, Z Zhou, LEA Young, S Emanuelle, CF Brainson, ... Cell metabolism 30 (5), 903-916. e7, 2019 | 78 | 2019 |
The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells Z Castaņo, CM Fillmore, CF Kim, SS McAllister Seminars in cancer biology 22 (5-6), 462-470, 2012 | 59 | 2012 |
H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression SP Rowbotham, F Li, AFM Dost, SM Louie, BP Marsh, P Pessina, ... Nature Communications 9 (1), 4559, 2018 | 53 | 2018 |
The epithelial sodium channel is a modifier of the long-term nonprogressive phenotype associated with F508del CFTR mutations PB Agrawal, R Wang, HL Li, K Schmitz-Abe, C Simone-Roach, J Chen, ... American journal of respiratory cell and molecular biology 57 (6), 711-720, 2017 | 31 | 2017 |
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation RC Sun, LEA Young, RC Bruntz, KH Markussen, Z Zhou, LR Conroy, ... Cell metabolism 33 (7), 1404-1417. e9, 2021 | 30 | 2021 |
BRG1 loss predisposes lung cancers to replicative stress and ATR dependency M Gupta, CP Concepcion, CG Fahey, H Keshishian, A Bhutkar, ... Cancer research 80 (18), 3841-3854, 2020 | 27 | 2020 |