Association among visual hallucinations, visual acuity, and specific eye pathologies in Alzheimer’s disease: treatment implications FM Chapman, J Dickinson, I McKeith, C Ballard American Journal of Psychiatry 156 (12), 1983-1985, 1999 | 175 | 1999 |
Carboplatin in combination with paclitaxel in advanced ovarian cancer: dose determination and pharmacokinetic and pharmacodynamic interactions. AH Calvert, A Boddy, NP Bailey, N Siddiqui, A Humphreys, A Hughes, ... Seminars in oncology 22 (5 Suppl 12), 91-8; discussion 99, 1995 | 70 | 1995 |
A phase I clinical study of the antipurine antifolate lometrexol (DDATHF) given with oral folic acid S Laohavinij, SR Wedge, MJ Lind, N Bailey, A Humphreys, M Proctor, ... Investigational new drugs 14, 325-335, 1996 | 57 | 1996 |
Hormesis results in trade-offs with immunity CD McClure, W Zhong, VL Hunt, FM Chapman, FV Hill, NK Priest Evolution 68 (8), 2225-2233, 2014 | 56 | 2014 |
Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer MJ Millward, DR Newell, K Yuen, JP Matthews, K Balmanno, CJ Charlton, ... Cancer chemotherapy and pharmacology 37, 161-167, 1995 | 28 | 1995 |
Long-term oral etoposide in metastatic breast cancer: clinical and pharmacokinetic results AH Calvert, MJ Lind, MM Millward, BMJ Cantwell, L Gumbrell, M Proctor, ... Cancer treatment reviews 19, 27-33, 1993 | 26 | 1993 |
Reductions in biomarkers of exposure to selected harmful and potentially harmful constituents following exclusive and partial switching from combustible cigarettes to myblu … P Morris, S McDermott, F Chapman, T Verron, X Cahours, M Stevenson, ... Internal and Emergency Medicine 17 (2), 397-410, 2022 | 25 | 2022 |
Phase I and pharmacokinetic study of a water-soluble etoposide prodrug, etoposide phosphate (BMY-40481) MJ Millward, DR Newell, V Mummaneni, LN Igwemezie, K Balmanno, ... European Journal of Cancer 31 (13-14), 2409-2411, 1995 | 21 | 1995 |
Polyfluoroaromatic stavudine (d4T) ProTides exhibit enhanced anti-HIV activity S Kandil, C Pannecouque, FM Chapman, AD Westwell, C McGuigan Bioorganic & Medicinal Chemistry Letters 29 (24), 126721, 2019 | 17 | 2019 |
The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols L Czekala, F Chapman, L Simms, K Rudd, E Trelles Sticken, R Wieczorek, ... Mutagenesis 36 (2), 129-142, 2021 | 15 | 2021 |
The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes L Simms, K Rudd, J Palmer, L Czekala, F Yu, F Chapman, ET Sticken, ... Current Research in Toxicology 1, 161-173, 2020 | 15 | 2020 |
Carboplatin and granulocyte colony-stimulating factor as first-line treatment for epithelial ovarian cancer: a phase I dose-intensity escalation study. AH Calvert, MJ Lind, S Ghazal-Aswad, L Gumbrell, MJ Millward, ... Seminars in Oncology 21 (5 Suppl 12), 1-6, 1994 | 15 | 1994 |
Phase I study of pharmacologically based dosing of carboplatin with filgrastim support in women with epithelial ovarian cancer. MJ Lind, S Ghazal-Aswad, L Gumbrell, K Fishwick, D Craigs, MJ Millward, ... Journal of clinical oncology 14 (3), 800-805, 1996 | 14 | 1996 |
A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic, pharmacodynamic and safety and tolerability profiles of tobacco-free oral nicotine pouches … F Chapman, S McDermott, K Rudd, V Taverner, M Stevenson, ... Psychopharmacology 239 (9), 2931-2943, 2022 | 13 | 2022 |
Preclinical Assessment of Tobacco-Free Nicotine Pouches Demonstrates Reduced In Vitro Toxicity Compared with Tobacco Snus and Combustible Cigarette Smoke F Yu, K Rudd, SJ Pour, E Trelles Sticken, O Dethloff, R Wieczorek, ... Applied in vitro toxicology 8 (1), 24-35, 2022 | 12 | 2022 |
Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action KE Chapman, EC Wilde, FM Chapman, JR Verma, UK Shah, ... Archives of Toxicology 95, 321-336, 2021 | 11 | 2021 |
A cancer research UK phase I trial of Phortress (novel antitumour benzothiazole) given intravenously in consecutive 21 day cycles with treatment on day 1 of each cycle M Seckl, N Cresti, A Boddy, R Phillips, F Chapman, P Schmid, H Calvert, ... Proceedings of the 8th NCRI Cancer Conference, Liverpool, UK, 4-7, 2012 | 11 | 2012 |
The use of granuloctye colony-stimulating factor to deliver four cycles of ifosfamide and epirubicin every 14 days in women with advanced or metastatic breast cancer MJ Lind, L Gumbrell, BMJ Cantwell, MJ Millward, D Simmonds, M Proctor, ... British journal of cancer 71 (3), 610-613, 1995 | 10 | 1995 |
Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette F Chapman, ET Sticken, R Wieczorek, SJ Pour, O Dethloff, J Budde, ... Toxicology in Vitro 86, 105510, 2023 | 9 | 2023 |
Comparison of passive-dosed and solvent spiked exposures of pro-carcinogen, benzo [a] pyrene, to human lymphoblastoid cell line, MCL-5 FM Chapman, C Sparham, C Hastie, DJ Sanders, R van Egmond, ... Toxicology in Vitro 67, 104905, 2020 | 9 | 2020 |