Ionizable lipid nanoparticle-mediated mRNA delivery for human CAR T cell engineering MM Billingsley, N Singh, P Ravikumar, R Zhang, CH June, MJ Mitchell Nano letters 20 (3), 1578-1589, 2020 | 342 | 2020 |
Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ... Cancer discovery 10 (4), 552-567, 2020 | 218 | 2020 |
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells Nature Medicine 27, 2021 | 107 | 2021 |
A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy SK Oda, KG Anderson, P Ravikumar, P Bonson, NM Garcia, CM Jenkins, ... Journal of Experimental Medicine 217 (12), e20191166, 2020 | 51 | 2020 |
Potentiating adoptive cell therapy using synthetic IL-9 receptors A Kalbasi, M Siurala, LL Su, M Tariveranmoshabad, LK Picton, ... Nature 607 (7918), 360-365, 2022 | 46 | 2022 |
Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells S Agarwal, MA Aznar, AJ Rech, CR Good, S Kuramitsu, T Da, M Gohil, ... Immunity 56 (10), 2388-2407. e9, 2023 | 19 | 2023 |
Single chain variable fragment linker length regulates CAR biology and T cell efficacy N Singh, NV Frey, B Engels, DM Barrett, O Shestova, P Ravikumar, ... Blood 134, 247, 2019 | 13 | 2019 |
Cheating death: a Fas-41BB immunomodulatory fusion protein obviates a death signal to enhance T cell function and adoptive therapy targeting leukemia and solid tumors SK Oda, KG Anderson, N Garcia, P Ravikumar, A Daman, P Bonson, ... The Journal of Immunology 200 (1_Supplement), 179.11-179.11, 2018 | 3 | 2018 |
Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors A Kalbasi, M Siurala, LL Su, M Tariveranmoshabad, LK Picton, ... Nature 612 (7938), E10, 2022 | 2 | 2022 |
Impaired tumor death receptor signaling drives resistance to CAR T cell therapy N Singh, O Shestova, P Ravikumar, KE Hayer, SJ Hong, EJ Orlando, ... bioRxiv, 627562, 2019 | 2 | 2019 |
Disruption of cell-intrinsic checkpoint regulator CTLA-4 in CD19 directed CAR T cells provides clinical efficacy in CLL patients S Agarwal, AA Gomez, T Da, S Kuramitsu, W Kong, P Ravikumar, M Gohil, ... Cancer Research 82 (12_Supplement), 5571-5571, 2022 | 1 | 2022 |
CAR T Cell Cytotoxicity Is Dependent on Death Receptor-Driven Apoptosis N Singh, O Shestova, K Hayer, A Hong, P Ravikumar, A Hoshino, ... Blood 132, 698, 2018 | 1 | 2018 |
175 A Fas-4–1BB immunomodulatory fusion protein converts a pro-death to a pro-survival signal, enhancing T cell function and efficacy of adoptive cell therapy in murine models … S Oda, K Anderson, P Greenberg, N Garcia, P Ravikumar, P Bonson, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | | 2020 |