| Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases AL Cardoso, A Fernandes, JA Aguilar-Pimentel, MH de Angelis, ... Ageing research reviews 47, 214-277, 2018 | 399 | 2018 |
| Cell-penetrating peptides—mechanisms of cellular uptake and generation of delivery systems S Trabulo, AL Cardoso, M Mano, MCP De Lima Pharmaceuticals 3 (4), 961-993, 2010 | 361 | 2010 |
| miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production AL Cardoso, JR Guedes, L Pereira de Almeida, MC Pedroso de Lima Immunology 135 (1), 73-88, 2012 | 339 | 2012 |
| MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma PM Costa, AL Cardoso, C Custódia, P Cunha, LP de Almeida, ... Journal of Controlled Release 207, 31-39, 2015 | 191 | 2015 |
| Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model JR Guedes, CM Custodia, RJ Silva, LP de Almeida, MC Pedroso de Lima, ... Human molecular genetics 23 (23), 6286-6301, 2014 | 172 | 2014 |
| siRNA delivery by a transferrin‐associated lipid‐based vector: a non‐viral strategy to mediate gene silencing ALC Cardoso, S Simoes, LP De Almeida, J Pelisek, C Culmsee, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007 | 128 | 2007 |
| Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, ... Molecular Therapy-Nucleic Acids 2, 2013 | 119 | 2013 |
| Roles of microglial and monocyte chemokines and their receptors in regulating Alzheimer's disease-associated amyloid-β and tau pathologies JR Guedes, T Lao, AL Cardoso, J El Khoury Frontiers in neurology 9, 381108, 2018 | 118 | 2018 |
| Tf-lipoplexes for neuronal siRNA delivery: a promising system to mediate gene silencing in the CNS ALC Cardoso, S Simoes, LP De Almeida, N Plesnila, MCP De Lima, ... Journal of controlled release 132 (2), 113-123, 2008 | 96 | 2008 |
| MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma PM Costa, AL Cardoso, C Nobrega, LF Pereira de Almeida, JN Bruce, ... Human molecular genetics 22 (5), 904-918, 2013 | 95 | 2013 |
| Involvement of microRNA in microglia‐mediated immune response J Guedes, ALC Cardoso, MC Pedroso de Lima Journal of Immunology Research 2013 (1), 186872, 2013 | 92 | 2013 |
| Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury M Teresa Girão da Cruz, ALC Cardoso, LP De Almeida, S Simoes, ... Gene therapy 12 (16), 1242-1252, 2005 | 81 | 2005 |
| MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease JR Guedes, I Santana, C Cunha, D Duro, MR Almeida, AM Cardoso, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 3, 7-17, 2016 | 79 | 2016 |
| miRNA-31 improves cognition and abolishes amyloid-β pathology by targeting APP and BACE1 in an animal model of Alzheimer’s disease AT Barros-Viegas, V Carmona, E Ferreiro, J Guedes, AM Cardoso, ... Molecular Therapy-Nucleic Acids 19, 1219-1236, 2020 | 78 | 2020 |
| Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions AL Cardoso, JR Guedes, MCP De Lima Current opinion in pharmacology 26, 1-9, 2016 | 76 | 2016 |
| Survivin silencing as a promising strategy to enhance the sensitivity of cancer cells to chemotherapeutic agents S Trabulo, AM Cardoso, T Santos-Ferreira, AL Cardoso, S Simoes, ... Molecular pharmaceutics 8 (4), 1120-1131, 2011 | 67 | 2011 |
| Gemini surfactants mediate efficient mitochondrial gene delivery and expression AM Cardoso, CM Morais, AR Cruz, AL Cardoso, SG Silva, ML do Vale, ... Molecular pharmaceutics 12 (3), 716-730, 2015 | 58 | 2015 |
| S4 (13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: Implications for cell internalization AMS Cardoso, S Trabulo, AL Cardoso, A Lorents, CM Morais, P Gomes, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (3), 877-888, 2012 | 58 | 2012 |
| Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice M Edfawy, JR Guedes, MI Pereira, M Laranjo, MJ Carvalho, X Gao, ... Nature communications 10 (1), 1431, 2019 | 55 | 2019 |
| Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo ALC Cardoso, P Costa, LP De Almeida, S Simoes, N Plesnila, C Culmsee, ... Journal of Controlled Release 142 (3), 392-403, 2010 | 55 | 2010 |
