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Nicholas Hoppe
Nicholas Hoppe
PhD Candidate, Aashish Manglik Lab, University of California - San Francisco
Verified email at ucsf.edu - Homepage
Title
Cited by
Cited by
Year
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6162020
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473-1479, 2020
3732020
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ...
Nature chemical biology 17 (1), 113-121, 2021
882021
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
BioRxiv, 2020
602020
Fusion protein strategies for cryo-EM study of G protein-coupled receptors
K Zhang, H Wu, N Hoppe, A Manglik, Y Cheng
Nature Communications 13 (1), 4366, 2022
352022
Autoantibody mimicry of hormone action at the thyrotropin receptor
B Faust, CB Billesbølle, CM Suomivuori, I Singh, K Zhang, N Hoppe, ...
Nature 609 (7928), 846-853, 2022
242022
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
ED Crawford, I Acosta, V Ahyong, EC Anderson, S Arevalo, D Asarnow, ...
PLoS pathogens 16 (10), e1008966, 2020
222020
Epistasis shapes the fitness landscape of an allosteric specificity switch
KK Nishikawa, N Hoppe, R Smith, C Bingman, S Raman
Nature Communications 12 (1), 5562, 2021
142021
Robust sequence determinants of α-synuclein toxicity in yeast implicate membrane binding
RW Newberry, T Arhar, J Costello, GC Hartoularos, AM Maxwell, ...
ACS chemical biology 15 (8), 2137-2153, 2020
112020
Consortium QSB, Walter P, Manglik A
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473, 2020
102020
Autoantibody and hormone activation of the thyrotropin G protein-coupled receptor
B Faust, I Singh, K Zhang, N Hoppe, AFM Pinto, Y Muftuoglu, ...
bioRxiv, 2022.01. 06.475289, 2022
42022
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway
N Hoppe, S Harrison, SH Hwang, Z Chen, M Karelina, I Deshpande, ...
Nature Structural & Molecular Biology, 1-11, 2024
32024
Molecular basis of proton-sensing by G protein-coupled receptors
MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrotra, ...
bioRxiv, 2024.04. 17.590000, 2024
2024
Sars-cov2 neutralizing single domain antibody constructs
P Walter, A Manglik, M Schoof, B Faust, N Hoppe, R Saunders, ...
US Patent App. 17/998,605, 2023
2023
Structural Insights into Orphan G Protein-Coupled Receptors: A Focus on GPR161 and Proton-Sensing GPCRs
N Hoppe
University of California, San Francisco, 2023
2023
Data for EMSL Project 51817 from May 2021
A Manglik, I Deshpande, N Hoppe, B Faust, C Billesboelle
Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2021
2021
An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation (preprint)
M Schoof, B Faust, RA Saunders, S Sangwan, VV Rezelj, N Hoppe, ...
2020
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
bioRxiv, 2020
2020
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