| WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner K Brown, P Yang, D Salvador, R Kulikauskas, H Ruohola-Baker, ... Oncogene 36 (22), 3119-3136, 2017 | 67 | 2017 |
| Clinical delineation of the PACS1‐related syndrome—Report on 19 patients JHM Schuurs‐Hoeijmakers, ML Landsverk, N Foulds, MK Kukolich, ... American Journal of Medical Genetics Part A 170 (3), 670-675, 2016 | 58 | 2016 |
| WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism V Sherwood, SK Chaurasiya, EJ Ekström, W Guilmain, Q Liu, T Koeck, ... Carcinogenesis 35 (4), 784-794, 2014 | 58 | 2014 |
| Bile acid-induced “Minority MOMP” promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1 Y Xu, DR Surman, L Diggs, S Xi, S Gao, D Gurusamy, K McLoughlin, ... Oncogene 39 (4), 877-890, 2020 | 27 | 2020 |
| Induction of thioredoxin-interacting protein by a histone deacetylase inhibitor, entinostat, is associated with DNA damage and apoptosis in esophageal adenocarcinoma PL Feingold, DR Surman, K Brown, Y Xu, LA McDuffie, V Shukla, ... Molecular cancer therapeutics 17 (9), 2013-2023, 2018 | 26 | 2018 |
| Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome V Ismail, LG Zachariassen, A Godwin, M Sahakian, S Ellard, KL Stals, ... The American Journal of Human Genetics 109 (7), 1217-1241, 2022 | 16 | 2022 |
| Bile acid and cigarette smoke enhance the aggressive phenotype of esophageal adenocarcinoma cells by downregulation of the mitochondrial uncoupling protein-2 Y Xu, PL Feingold, DR Surman, K Brown, S Xi, JL Davis, J Hernandez, ... Oncotarget 8 (60), 101057, 2017 | 10 | 2017 |
| Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants L Loong, C Cubuk, S Choi, S Allen, B Torr, A Garrett, C Loveday, M Durkie, ... Genetics in Medicine 24 (3), 552-563, 2022 | 6 | 2022 |
| Therapeutic synergy in esophageal cancer and mesothelioma is predicted by dynamic BH3 profiling DR Surman, Y Xu, MJ Lee, J Trepel, K Brown, M Ramineni, TG Splawn, ... Molecular cancer therapeutics 20 (8), 1469-1480, 2021 | 4 | 2021 |
| Cloning and pharmacological characterization of CCR7, CCL21 and CCL19 from Macaca fascicularis R Moxley, E Day, K Brown, M Mahnke, M Zurini, R Schmitz, CE Jones, ... European journal of pharmaceutical sciences 37 (3-4), 264-271, 2009 | 3 | 2009 |
| Persistence of smoking mutational signatures in the non-small cell lung cancer genome CR Lindsay, P Nicola, A Gruber, K Brown, M Carter, H Adderley, S Rafee, ... Cancer Research 83 (7_Supplement), 6463-6463, 2023 | 1 | 2023 |
| Targeting mutant p53-R248W reactivates WT p53 function and alters the onco-metabolic profile K Brown, LMM Jenkins, DR Crooks, DR Surman, SJ Mazur, Y Xu, ... Frontiers in Oncology 12, 1094210, 2023 | 1 | 2023 |
| 94 Clinical outcomes in advanced Non-Small Cell Lung Cancer (NSCLC) with METexon 14 skipping mutation M Smith, M Carter, L Woodhouse, H Adderley, G Morrissey, K Brown, ... Lung Cancer 190, 2024 | | 2024 |
| New syndromic combined immunodeficiency with severe neurodevelopmental defects caused by biallelic null variants in the PPM1D gene A Esteve-Sole, LI González-Granado, L Pias, AV Marin, K Brown, ... Clinical Immunology 250, 109588, 2023 | | 2023 |
| Outcomes for platinum doublet chemotherapy before and after first-line immune checkpoint inhibition in advanced non-small cell lung cancer (NSCLC) J Lewis, L Woodhouse, H Adderley, M Carter, K Brown, G Morrissey, ... | | 2023 |
| eP360: Exome analysis of prenatal and postnatal cases referred with skeletal dysplasia-overview of phenotypic and genomic and findings A Haworth, T Homfray, S Drury, R Dubis, M McEntagart, KT Brown, ... Genetics in Medicine 24 (3), S226, 2022 | | 2022 |
| Bile Acids may Induce Esophageal Carcinogenesis through Induction of Minority Momp Y Xu, D Surman, PL Feingold, K Brown, JL Davis, DS Schrump, RT Ripley Gastroenterology 152 (5), S663, 2017 | | 2017 |
| Clinical delineation of the recurrent de novo c. 607C> T mutation in PACS1 JHM Schuurs-Hoeijmakers, ML Landsverk, N Foulds, MK Kukolich, ... European Human Genetics Conference 2017, 2017 | | 2017 |
| Cigarette smoke and bile acids induce metabolic reprogramming mediated by uncoupling protein-2 (UCP2) during esophageal carcinogenesis Y Xu, K Brown, DR Depew, PL Feingold, M Rao, J Davis, DS Schrump, ... Cancer Research 76 (14_Supplement), 1033-1033, 2016 | | 2016 |
| Mitochondrial inhibition decreases the malignant phenotype of esophageal adenocarcinoma cells through the induction of autophagy DR Depew, PL Feingold, K Brown, Y Xu, M Rao, M Moses, LM Neckers, ... Cancer Research 76 (14_Supplement), 1005-1005, 2016 | | 2016 |
