Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library S Dawadi, N Simmons, G Miklossy, KM Bohren, JC Faver, MN Ucisik, ... Proceedings of the National Academy of Sciences 117 (29), 16782-16789, 2020 | 50 | 2020 |
Discovery and characterization of bromodomain 2–specific inhibitors of BRDT Z Yu, AF Ku, JL Anglin, R Sharma, MN Ucisik, JC Faver, F Li, ... Proceedings of the National Academy of Sciences 118 (9), e2021102118, 2021 | 49 | 2021 |
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors S Chamakuri, S Lu, MN Ucisik, KM Bohren, YC Chen, HC Du, JC Faver, ... Proceedings of the National Academy of Sciences 118 (36), e2111172118, 2021 | 47 | 2021 |
Equivalency challenge: Evaluation of Lipodox® as the generic equivalent for Doxil® in a human ovarian cancer orthotropic mouse model JA Smith, L Mathew, M Burney, P Nyshadham, RL Coleman Gynecologic oncology 141 (2), 357-363, 2016 | 38 | 2016 |
Identifying oxacillinase-48 carbapenemase inhibitors using DNA-encoded chemical libraries DM Taylor, J Anglin, S Park, MN Ucisik, JC Faver, N Simmons, Z Jin, ... ACS infectious diseases 6 (5), 1214-1227, 2020 | 34 | 2020 |
Homogeneous and functional group tolerant ring-closing metathesis for DNA-encoded chemical libraries OBC Monty, P Nyshadham, KM Bohren, M Palaniappan, MM Matzuk, ... ACS combinatorial science 22 (2), 80-88, 2020 | 32 | 2020 |
Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment L Mathew, M Burney, A Gaikwad, P Nyshadham, EK Nugent, A Gonzalez, ... Integrative Cancer Therapies 16 (4), 572-584, 2017 | 27 | 2017 |
Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections RK Modukuri, Z Yu, Z Tan, HM Ta, MN Ucisik, Z Jin, JL Anglin, KL Sharma, ... Proceedings of the National Academy of Sciences 119 (22), e2122506119, 2022 | 22 | 2022 |
Mammalian target of rapamycin complex 2 signaling is required for liver regeneration in a cholestatic liver injury murine model Y Zhou, M Xu, P Liu, B Liang, M Qian, H Wang, X Song, P Nyshadham, ... The American journal of pathology 190 (7), 1414-1426, 2020 | 11 | 2020 |
Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library S Chamakuri, MK Chung, ELG Samuel, KA Tran, YC Chen, P Nyshadham, ... Bioorganic & Medicinal Chemistry 48, 116387, 2021 | 10 | 2021 |
Metabolism of a selective serotonin and norepinephrine reuptake inhibitor duloxetine in liver microsomes and mice X Qin, JM Hakenjos, KR MacKenzie, M Barzi, H Chavan, P Nyshadham, ... Drug Metabolism and Disposition 50 (2), 128-139, 2022 | 8 | 2022 |
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors R Jimmidi, S Chamakuri, S Lu, MN Ucisik, PJ Chen, KM Bohren, ... Communications Chemistry 6 (1), 164, 2023 | 2 | 2023 |
Identifying Metabolic Pathways of c‐MET Tyrosine Kinase Inhibitor Tepotinib in Human and Mouse Liver Microsomes F Li, KR MacKenzie, P Nyshadham, KA Kerlec, MM Matzuk The FASEB Journal 34 (S1), 1-1, 2020 | 2 | 2020 |
Effective Gene Therapy for Hemophilia a: Novel Re-Dosable Non-Viral Formulation That Provides Stable, and Durable FVIII Expression with Improved Tolerability B Truong, K Hajj, J Schwerk, D Zhang, J Tamayo, G Guzelsoy, J Kubicki, ... Blood 142, 1232, 2023 | 1 | 2023 |
Cyp1a2‐knockout increases the systemic exposure of a serotonin and norepinephrine reuptake inhibitor duloxetine in mice X Qin, C Xie, JM Hakenjos, KM Mackenzie, M Barzi, P Nyshadham, ... The FASEB Journal 36, 2022 | 1 | 2022 |
Corrigendum to ‘Equivalency challenge: evaluation of Lipodox® as the generic equivalent for Doxil® in a human ovarian cancer orthotropic mouse model’[Gynecol. Oncol. 141 (2016 … JA Smith, L Mathew, M Burney, P Nyshadham, RL Coleman Gynecologic oncology 144 (2), 448, 2017 | 1 | 2017 |
Equivalency challenge: evaluation of Lipodox as the generic equivalent for Doxil in a human ovarian cancer orthotropic mouse model (vol 141, pg 357, 2016) JA Smith, L Mathew, M Burney, P Nyshadham, RL Coleman GYNECOLOGIC ONCOLOGY 144 (2), 448-448, 2017 | 1 | 2017 |