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David Cobb
David Cobb
Unknown affiliation
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
The exported chaperone PfHsp70x is dispensable for the Plasmodium falciparum intraerythrocytic life cycle
DW Cobb, A Florentin, MA Fierro, M Krakowiak, JM Moore, ...
MSphere 2 (5), 10.1128/msphere. 00363-17, 2017
532017
PfClpC is an essential Clp chaperone required for plastid integrity and Clp protease stability in Plasmodium falciparum
A Florentin, DW Cobb, JD Fishburn, MJ Cipriano, PS Kim, MA Fierro, ...
Cell reports 21 (7), 1746-1756, 2017
432017
An endoplasmic reticulum CREC family protein regulates the egress proteolytic cascade in malaria parasites
MA Fierro, B Asady, CF Brooks, DW Cobb, A Villegas, SNJ Moreno, ...
MBio 11 (1), 10.1128/mbio. 03078-19, 2020
242020
The endoplasmic reticulum chaperone PfGRP170 is essential for asexual development and is linked to stress response in malaria parasites
HM Kudyba, DW Cobb, MA Fierro, A Florentin, D Ljolje, B Singh, ...
Cellular microbiology 21 (9), e13042, 2019
242019
CRISPR/Cas9 gene editing to make conditional mutants of human malaria parasite P. falciparum
HM Kudyba, DW Cobb, A Florentin, M Krakowiak, V Muralidharan
JoVE (Journal of Visualized Experiments), e57747, 2018
212018
Some conditions apply: Systems for studying Plasmodium falciparum protein function
HM Kudyba, DW Cobb, J Vega-Rodríguez, V Muralidharan
PLoS Pathogens 17 (4), e1009442, 2021
202021
Directing traffic: Chaperone‐mediated protein transport in malaria parasites
A Florentin, DW Cobb, HM Kudyba, V Muralidharan
Cellular microbiology 22 (7), e13215, 2020
152020
A redox-active crosslinker reveals an essential and inhibitable oxidative folding network in the endoplasmic reticulum of malaria parasites
DW Cobb, HM Kudyba, A Villegas, MR Hoopmann, RP Baptista, B Bruton, ...
PLoS pathogens 17 (2), e1009293, 2021
112021
Time-resolved proximity biotinylation implicates a porin protein in export of transmembrane malaria parasite effectors
D Anaguano, W Dedkhad, CF Brooks, DW Cobb, V Muralidharan
Journal of Cell Science 136 (20), 2023
62023
Structural parasitology of the malaria parasite Plasmodium falciparum
L Anton, DW Cobb, CM Ho
Trends in Biochemical Sciences 47 (2), 149-159, 2022
52022
An endoplasmic reticulum CREC family protein regulates the egress proteolytic cascade in malaria parasites. mBio 11: e03078-19
MA Fierro, B Asady, CF Brooks, DW Cobb, A Villegas, SNJ Moreno, ...
Web of Science, 2020
52020
A druggable oxidative folding pathway in the endoplasmic reticulum of human malaria parasites
DW Cobb, HM Kudyba, A Villegas, MR Hoopmann, R Baptista, B Bruton, ...
bioRxiv, 2020.05. 13.093591, 2020
22020
Rapid, time-resolved proximity labeling by sbp1 identifies a porin domain protein at the malaria parasite periphery
D Anaguano, CF Brooks, DW Cobb, V Muralidharan
bioRxiv, 2022.06. 30.498261, 2022
12022
Activity-based Crosslinking to Identify Substrates of Thioredoxin-domain Proteins in Malaria Parasites
DW Cobb, GS Woods, V Muralidharan
Bio-protocol 12 (4), e4322-e4322, 2022
12022
Multiscale effects of perturbed translation dynamics inform antimalarial design
L Anton, W Cheng, MT Haile, DW Cobb, X Zhu, L Han, E Li, A Nair, ...
bioRxiv, 2023.09. 03.556115, 2023
2023
Visualizing Plasmodium falciparum ultrastructure at subnanometre resolution across the asexual blood stages using in situ cryo-ET
W Cheng, L Anton, M Haile, D Cobb, CM Ho
Acta Crystallographica Section A: Foundations of Crystallography 79, a379-a379, 2022
2022
Dissecting M5717 Killing of Malaria Parasites
M Haile, J Cheng, L Anton, D Cobb, C Lee, CM Ho
Acta Crystallographica Section A: Foundations of Crystallography 79, a375-a375, 2022
2022
Genetic and Chemical Approaches Reveal Function and Druggability of Chaperones in the Human Malaria Parasite Plasmodium falciparum
DW Cobb
University of Georgia, 2020
2020
An ER CREC family protein regulates the egress proteolytic cascade in malaria parasites
MA Fierro, B Asady, CF Brooks, DW Cobb, A Villegas, SNJ Moreno, ...
bioRxiv, 457481, 2019
2019
The ER chaperone PfGRP170 is essential for asexual development and is linked to stress response in malaria parasites
HM Kudyba, DW Cobb, MA Fierro, A Florentin, D Ljolje, B Singh, ...
bioRxiv, 406181, 2018
2018
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