| Clinical and therapeutic relevance of cancer-associated fibroblasts Y Chen, KM McAndrews, R Kalluri Nature reviews Clinical oncology 18 (12), 792-804, 2021 | 516 | 2021 |
| Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer Y Chen, J Kim, S Yang, H Wang, CJ Wu, H Sugimoto, VS LeBleu, ... Cancer cell 39 (4), 548-565. e6, 2021 | 315 | 2021 |
| Identification of functional heterogeneity of carcinoma-associated fibroblasts with distinct IL6-mediated therapy resistance in pancreatic cancer KM McAndrews, Y Chen, JK Darpolor, X Zheng, S Yang, JL Carstens, B Li, ... Cancer discovery 12 (6), 1580-1597, 2022 | 118 | 2022 |
| Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways Y Chen, S Wang, X Lu, H Zhang, Y Fu, Y Luo Blood, The Journal of the American Society of Hematology 117 (23), 6392-6403, 2011 | 108 | 2011 |
| Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer Y Chen, S Yang, J Tavormina, D Tampe, M Zeisberg, H Wang, ... Cancer Cell 40 (8), 818-834. e9, 2022 | 89 | 2022 |
| The nuclear translocation of endostatin is mediated by its receptor nucleolin in endothelial cells N Song, Y Ding, W Zhuo, T He, Z Fu, Y Chen, X Song, Y Fu, Y Luo Angiogenesis 15, 697-711, 2012 | 79 | 2012 |
| Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program Y Chen, VS LeBleu, JL Carstens, H Sugimoto, X Zheng, S Malasi, D Saur, ... EMBO molecular medicine 10 (10), e9085, 2018 | 77 | 2018 |
| Therapeutic targeting of STAT3 employing small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis M Tang, Y Chen, B Li, H Sugimoto, S Yang, C Yang, VS LeBleu, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 58 | 2021 |
| Enhancement of tumor uptake and therapeutic efficacy of EGFR‐targeted antibody cetuximab and antibody–drug conjugates by cholesterol sequestration Y Chen, G Liu, L Guo, H Wang, Y Fu, Y Luo International journal of cancer 136 (1), 182-194, 2015 | 51 | 2015 |
| Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta Y Chen, S Yang, S Lovisa, CG Ambrose, KM McAndrews, H Sugimoto, ... Nature communications 12 (1), 7199, 2021 | 50 | 2021 |
| Heat shock cognate 70 regulates the translocation and angiogenic function of nucleolin Y Ding, N Song, C Liu, T He, W Zhuo, X He, Y Chen, X Song, Y Fu, Y Luo Arteriosclerosis, thrombosis, and vascular biology 32 (9), e126-e134, 2012 | 50 | 2012 |
| Prognostic significance of the combined score of endothelial expression of nucleolin and CD31 in surgically resected non-small cell lung cancer H Zhao, Y Huang, C Xue, Y Chen, X Hou, Y Guo, L Zhao, ZH Hu, Y Huang, ... PloS one 8 (1), e54674, 2013 | 41 | 2013 |
| Endostatin prevents dietary-induced obesity by inhibiting adipogenesis and angiogenesis H Wang, Y Chen, X Lu, G Liu, Y Fu, Y Luo Diabetes 64 (7), 2442-2456, 2015 | 39 | 2015 |
| Specific chemotherapeutic agents induce metastatic behaviour through stromal‐and tumour‐derived cytokine and angiogenic factor signalling G Liu, Y Chen, F Qi, L Jia, X Lu, T He, Y Fu, L Li, Y Luo The Journal of pathology 237 (2), 190-202, 2015 | 36 | 2015 |
| PLCγ1–PKCγ Signaling‐Mediated Hsp90α Plasma Membrane Translocation Facilitates Tumor Metastasis J Yang, X Song, Y Chen, X Lu, Y Fu, Y Luo Traffic 15 (8), 861-878, 2014 | 31 | 2014 |
| The heparin binding motif of endostatin mediates its interaction with receptor nucleolin Y Fu, Y Chen, X Luo, Y Liang, H Shi, L Gao, S Zhan, D Zhou, Y Luo Biochemistry 48 (49), 11655-11663, 2009 | 26 | 2009 |
| A combined effect of the KPNA3 and KPNB3 genes on susceptibility to schizophrenia H Zhang, G Ju, J Wei, Y Hu, L Liu, Q Xu, Y Chen, Z Sun, S Liu, Y Yu, ... Neuroscience letters 402 (1-2), 173-175, 2006 | 20 | 2006 |
| Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis Y Chen, D Keskin, H Sugimoto, K Kanasaki, PE Phillips, L Bizarro, ... PLoS biology 16 (12), e2005907, 2018 | 19 | 2018 |
| Endostatin specifically targets both tumor blood vessels and lymphatic vessels W Zhuo, Y Chen, X Song, Y Luo Frontiers of medicine 5 (4), 336-340, 2011 | 19 | 2011 |
| Pre-clinical toxicokinetics and safety study of M2ES, a PEGylated recombinant human endostatin, in rhesus monkeys L Guo, X Geng, Y Chen, F Qi, L Liu, Y Miao, Z Lin, M Yu, Z Li, Y Fu, B Li, ... Regulatory Toxicology and Pharmacology 69 (3), 512-523, 2014 | 13 | 2014 |
