| Flexible Fragment Growing Boosts Potency of Quorum‐Sensing Inhibitors against Pseudomonas aeruginosa Virulence M Zender, F Witzgall, A Kiefer, B Kirsch, CK Maurer, AM Kany, N Xu, ... ChemMedChem 15 (2), 188-194, 2020 | 30 | 2020 |
| Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum A Kiefer, CD Bader, J Held, A Esser, J Rybniker, M Empting, R Müller, ... Chemistry–A European Journal 25 (37), 8894-8902, 2019 | 26 | 2019 |
| Sandacrabins–Structurally unique antiviral RNA polymerase inhibitors from a rare myxobacterium CD Bader, F Panter, R Garcia, EP Tchesnokov, S Haid, C Walt, C Spröer, ... Chemistry–A European Journal 28 (10), e202104484, 2022 | 10 | 2022 |
| Syntheses of Cyclomarins–Interesting Marine Natural Products with Distinct Mode of Action towards Malaria and Tuberculosis A Kiefer, U Kazmaier Synthesis 51 (01), 107-121, 2019 | 7 | 2019 |
| Synthesis of modified β-methoxyphenylalanines via diazonium chemistry and their incorporation in desoxycyclomarin analogues A Kiefer, U Kazmaier Organic & Biomolecular Chemistry 17 (1), 88-102, 2019 | 7 | 2019 |
| The many facets of sulfur incorporation in natural product biosynthesis AD Steele, AF Kiefer, B Shen Current Opinion in Chemical Biology 76, 102366, 2023 | 5 | 2023 |
| Phage display-based discovery of cyclic peptides against the broad spectrum bacterial anti-virulence target CsrA V Jakob, BGE Zoller, J Rinkes, Y Wu, AF Kiefer, M Hust, S Polten, ... European journal of medicinal chemistry 231, 114148, 2022 | 5 | 2022 |
| Palladium‐Catalyzed Allylic Alkylation Reactions of Glycolates as a Tool for the Synthesis of Functionalized α‐Hydroxy Esters A Kiefer, D Gawas, U Kazmaier European Journal of Organic Chemistry 2015 (26), 5810-5816, 2015 | 5 | 2015 |
| Structure-guided optimization of small-molecule folate uptake inhibitors targeting the energy-coupling factor transporters AF Kiefer, S Bousis, MM Hamed, E Diamanti, J Haupenthal, AKH Hirsch Journal of Medicinal Chemistry 65 (13), 8869-8880, 2022 | 4 | 2022 |
| Application of a biocatalytic strategy for the preparation of tiancimycin-based antibody–drug conjugates revealing key insights into structure–activity relationships AD Steele, AF Kiefer, D Hwang, D Yang, CN Teijaro, A Adhikari, C Rader, ... Journal of Medicinal Chemistry 66 (2), 1562-1573, 2023 | 3 | 2023 |
| Insights into the biosynthesis of icumazole, unveiling a distinctive family of crotonyl-CoA carboxylase/reductase F Xie, AF Kiefer, AKH Hirsch, OV Kalinina, C Fu, R Müller Cell Reports Physical Science 4 (5), 2023 | 2 | 2023 |
| pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA Y Liu, S Ashmawy, L Latta, AV Weiss, AF Kiefer, S Nasr, B Loretz, ... Biomacromolecules 24 (8), 3742-3754, 2023 | 1 | 2023 |
| An Artificial In Vitro Metabolism to Angiopterlactone B Inspired by Traditional Retrosynthesis AF Kiefer, YC Liu, R Gummerer, C Jäger, J Deska Angewandte Chemie International Edition 62 (23), e202301178, 2023 | 1 | 2023 |
| Ein künstlicher in vitro‐Stoffwechsel zu Angiopterlacton B nach dem Vorbild traditioneller Retrosynthese AF Kiefer, YC Liu, R Gummerer, C Jäger, J Deska Angewandte Chemie 135 (23), e202301178, 2023 | 1 | 2023 |
| A fully biocatalytic approach to angiopterlactone B based on a chemoinspired artificial in vitro metabolism A Kiefer, YC Liu, R Gummerer, C Jäger, J Deska | 1 | 2023 |
| The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity E Kalkreuter, SA Kautsar, D Yang, CN Teijaro, CD Bader, LL Fluegel, ... bioRxiv, 2023.12. 14.571759, 2023 | 1 | 2023 |
| Unlocking the Antiviral Arsenal: Multiparametric Optimization of Small-Molecule Inhibitors against RSV and hCoV-229E C Karhan, SM Sake, AP Gunesch, C Grethe, B Hellwinkel, AF Kiefer, ... | | 2024 |
| INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LasB C Ducho, RW Hartmann, J Haupenthal, AKH Hirsch, A Kany, C Kaya, ... US Patent App. 18/042,907, 2023 | | 2023 |
| ANTHRAQUINONE-FUSED ENEDIYNE DERIVED ANTIBODY-DRUG CONJUGATES–A BIOCATALYTIC AND SEMISYNTHETIC APPROACH A Kiefer, A Steele, D Hwang, D Yang, C Teijaro, A Adhikari, Y Jiang, ... 4th International Conference on Natural Product Discovery and Development in …, 2023 | | 2023 |
| BIOSYNTHESIS OF THE BENZOXAZOLINATE MOIETY IN C-1027 PROCEEDS VIA CoA-TETHERED INTERMEDIATES L Lauterbach, K Viehrig, HM Ge, D Yang, A Steele, A Kiefer, B Shen 4th International Conference on Natural Product Discovery and Development in …, 2023 | | 2023 |
