| Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto, X Zhang, ... Cell research 30 (8), 678-692, 2020 | 758 | 2020 |
| Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L MD Sacco, C Ma, P Lagarias, A Gao, JA Townsend, X Meng, P Dube, ... Science Advances 6 (50), eabe0751, 2020 | 347 | 2020 |
| Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are nonspecific promiscuous SARS-CoV-2 main protease inhibitors C Ma, Y Hu, JA Townsend, PI Lagarias, MT Marty, A Kolocouris, J Wang ACS pharmacology & translational science 3 (6), 1265-1277, 2020 | 226 | 2020 |
| Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and a FlipGFP-based reporter assay C Ma, MD Sacco, Z Xia, G Lambrinidis, JA Townsend, Y Hu, X Meng, ... ACS central science 7 (7), 1245-1260, 2021 | 129 | 2021 |
| Expedited approach toward the rational design of noncovalent SARS-CoV-2 main protease inhibitors N Kitamura, MD Sacco, C Ma, Y Hu, JA Townsend, X Meng, F Zhang, ... Journal of medicinal chemistry 65 (4), 2848-2865, 2021 | 124 | 2021 |
| Discovery of di-and trihaloacetamides as covalent SARS-CoV-2 main protease inhibitors with high target specificity C Ma, Z Xia, MD Sacco, Y Hu, JA Townsend, X Meng, J Choza, H Tan, ... Journal of the American Chemical Society 143 (49), 20697-20709, 2021 | 103 | 2021 |
| Native mass spectrometry of antimicrobial peptides in lipid nanodiscs elucidates complex assembly LR Walker, EM Marzluff, JA Townsend, WC Resager, MT Marty Analytical chemistry 91 (14), 9284-9291, 2019 | 53 | 2019 |
| Imidazole derivatives improve charge reduction and stabilization for native mass spectrometry JA Townsend, JE Keener, ZM Miller, JS Prell, MT Marty Analytical chemistry 91 (22), 14765-14772, 2019 | 44 | 2019 |
| Influenza AM2 channel Oligomerization is sensitive to its chemical environment JA Townsend, HM Sanders, AD Rolland, CK Park, NC Horton, JS Prell, ... Analytical chemistry 93 (48), 16273-16281, 2021 | 17 | 2021 |
| A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile MD Sacco, S Wang, SR Adapa, X Zhang, EM Lewandowski, MV Gongora, ... Nature communications 13 (1), 4370, 2022 | 12 | 2022 |
| Copper-free click enabled triazabutadiene for bioorthogonal protein functionalization AN Wijetunge, GJ Davis, M Shadmehr, JA Townsend, MT Marty, ... Bioconjugate chemistry 32 (2), 254-258, 2021 | 12 | 2021 |
| Protein modification via mild photochemical isomerization of triazenes to release aryl diazonium ions GJ Davis, JA Townsend, MG Morrow, M Hamie, AJ Shepard, CC Hsieh, ... Bioconjugate chemistry 32 (11), 2432-2438, 2021 | 8 | 2021 |
| Suzuki Coupling of Protected Aryl Diazonium Ions: Expanding the Knowledge of Triazabutadiene Compatible Reactions AJ Shepard, JA Townsend, C Foley, C Hulme, MT Marty, JC Jewett Organic letters 23 (5), 1851-1855, 2021 | 6 | 2021 |
| What’s the defect? Using mass defects to study oligomerization of membrane proteins and peptides in nanodiscs with native mass spectrometry JA Townsend, MT Marty Methods, 2023 | 2 | 2023 |
| Differences in oligomerization of the SARS-CoV-2 envelope protein, poliovirus VP4, and HIV Vpu JA Townsend, O Fapohunda, Z Wang, H Pham, MT Taylor, B Kloss, ... Biochemistry 63 (3), 241-250, 2024 | 1 | 2024 |
| A unique class of Zn2+-binding PBPs underlies cephalosporin resistance and sporogenesis of Clostridioides difficile MD Sacco, S Wang, SR Adapa, X Zhang, MV Gongora, JR Gatdula, ... bioRxiv, 2022.01. 04.474981, 2022 | 1 | 2022 |
| An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity N Kitamura, MD Sacco, C Ma, Y Hu, JA Townsend, X Meng, F Zhang, ... bioRxiv, 2020.12. 19.423537, 2020 | 1 | 2020 |
| Differences in Oligomerization of the SARS-CoV-2 Envelope Protein, Poliovirus VP4, and HIV Vpu (preprint) JA Townsend, O Fapohunda, Z Wang, H Pham, MT Taylor, B Kloss, ... | | 2023 |
| Analysis of Viroporins and Membrane Systems With Native Mass Spectrometry J Townsend The University of Arizona, 2023 | | 2023 |
| Correction to Copper-Free Click Enabled Triazabutadiene for Bioorthogonal Protein Functionalization AN Wijetunge, GJ Davis, M Shadmehr, JA Townsend, LE Guzmán, ... Bioconjugate Chemistry 33 (3), 541-541, 2022 | | 2022 |
