| Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy CS Ward, HS Venkatesh, MM Chaumeil, AH Brandes, M VanCriekinge, ... Cancer research 70 (4), 1296-1305, 2010 | 183 | 2010 |
| Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer JC Villa, D Chiu, AH Brandes, FE Escorcia, CH Villa, WF Maguire, CJ Hu, ... Cell reports 8 (4), 1077-1092, 2014 | 141 | 2014 |
| Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas FC Geyer, A Li, AD Papanastasiou, A Smith, P Selenica, KA Burke, ... Nature communications 9 (1), 1816, 2018 | 132 | 2018 |
| Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors F Pareja, AH Brandes, T Basili, P Selenica, FC Geyer, D Fan, ... Nature Communications 9 (1), 3533, 2018 | 108 | 2018 |
| PAX8–GLIS3 gene fusion is a pathognomonic genetic alteration of hyalinizing trabecular tumors of the thyroid C Marchiò, A Da Cruz Paula, R Gularte-Merida, T Basili, A Brandes, ... Modern Pathology 32 (12), 1734-1743, 2019 | 42 | 2019 |
| 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased … AH Brandes, CS Ward, SM Ronen Breast Cancer Research 12, 1-14, 2010 | 40 | 2010 |
| HDAC inhibition induces increased choline uptake and elevated phosphocholine levels in MCF7 breast cancer cells CS Ward, P Eriksson, JL Izquierdo-Garcia, AH Brandes, SM Ronen PloS one 8 (4), e62610, 2013 | 37 | 2013 |
| Preclinical proof of concept for VivoVec, a lentiviral-based platform for in vivo CAR T-cell engineering KR Michels, A Sheih, SA Hernandez, AH Brandes, D Parrilla, B Irwin, ... Journal for immunotherapy of cancer 11 (3), 2023 | 13 | 2023 |
| Abstract PD4-13: Estrogen receptor-negative breast adenomyoepitheliomas are driven by co-occurring HRAS hotspot and PI3K pathway gene mutations: A genetic … FC Geyer, A Li, AD Papanastasiou, A Smith, P Selenica, KA Burke, ... Cancer Research 78 (4_Supplement), PD4-13-PD4-13, 2018 | 3 | 2018 |
| Preclinical development of PR006, a gene therapy for the treatment of frontotemporal dementia with progranulin mutations: Molecular and cell biology/endosomal‐lysosomal dysfunction LD Heckman, SR Burstein, A Brandes, LC Wong, Z Yang, HN Lin, T Fenn, ... Alzheimer's & Dementia 16, e043632, 2020 | 2 | 2020 |
| Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results J Sevigny, O Uspenskaya, LD Heckman, LC Wong, DA Hatch, A Tewari, ... Nature Medicine, 1-10, 2024 | | 2024 |
| 438 In vivo Engineered CAR-T cells for oncology using a surface-engineered lentivirus platform: nonclinical safety and biodistribution A Brandes, SM Koo, D Parilla, S Hernandez, C Nicolai, A Sheih, A Ting, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
| Preclinical Activity and Safety of UB-VV100, A Novel Lentiviral Vector Product Designed for Selective and Effective In Vivo Engineering of Therapeutic Anti-CD19 CART Cells for … AH Brandes, S Geisinger, A Sheih, A Ting, K Michels, SA Hernandez, ... MOLECULAR THERAPY 30 (4), 579-580, 2022 | | 2022 |
| PR006, an AAV Gene Therapy Vector Expressing Progranulin, Improved FTD-GRN Phenotypes In Vitro and In Vivo LD Heckman, SR Burstein, A Brandes, LC Wong, Z Yang, HN Lin, T Fenn, ... MOLECULAR THERAPY 28 (4), 561-561, 2020 | | 2020 |
| Gene therapy PR006 increased progranulin levels and improved lysosomal related phenotypes in model systems A Brandes, LD Heckman, LC Wong, Z Yang, T Fenn, S Nelson, Z Aziz, ... Abstracts/Molecular Genetics and Metabolism 129, S16-S167, 2019 | | 2019 |
| Estrogen receptor-negative breast adenomyoepitheliomas are driven by co-occurring HRAS hotspot and PI3K pathway gene mutations: A genetic and functional analysis FC Geyer, A Li, AD Papanastasiou, A Smith, P Selenica, KA Burke, ... CANCER RESEARCH 78 (4), 2018 | | 2018 |
| Regulation of Notch signaling by γ-secretase protein modulators AH Brandes Weill Medical College of Cornell University, 2016 | | 2016 |
| HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells S Ronen, CS Ward, P Eriksson, JL Izquierdo-Garcia, AH Brandes, ... | | 2013 |
| MRS detection of altered choline metabolism following HSP90 inhibition A Brandes, CS Ward, JS Hwang, SM Ronen Proc. Intl. Soc. Mag. Reson. Med 18, 654, 2010 | | 2010 |
| Abstract# 3417: Noninvasive monitoring of PI3K inhibition: Detection of reduced pyruvate to lactate conversion by hyperpolarized 13C MRS H Venkatesh, C Ward, A Brandes, M van Criekinge, H Dafni, ... Cancer Research 69 (9_Supplement), 3417-3417, 2009 | | 2009 |
