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Patrick M. Schaefer
Patrick M. Schaefer
Children's Hospital of Philadelphia
No verified email
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Year
NADH autofluorescence—a marker on its way to boost bioenergetic research
PM Schaefer, S Kalinina, A Rueck, CAF von Arnim, B von Einem
Cytometry Part A 95 (1), 34-46, 2019
1792019
Lactate limits T cell proliferation via the NAD (H) redox state
WJ Quinn, J Jiao, T TeSlaa, J Stadanlick, Z Wang, L Wang, T Akimova, ...
Cell reports 33 (11), 2020
1692020
Host mitochondria influence gut microbiome diversity: A role for ROS
T Yardeni, CE Tanes, K Bittinger, LM Mattei, PM Schaefer, LN Singh, ...
Science signaling 12 (588), eaaw3159, 2019
1282019
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy
PK Kopinski, KA Janssen, PM Schaefer, S Trefely, CE Perry, P Potluri, ...
Proceedings of the National Academy of Sciences 116 (32), 16028-16035, 2019
1252019
Correlative NAD (P) H‐FLIM and oxygen sensing‐PLIM for metabolic mapping
S Kalinina, J Breymayer, P Schäfer, E Calzia, V Shcheslavskiy, W Becker, ...
Journal of biophotonics 9 (8), 800-811, 2016
892016
Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress
S Menges, G Minakaki, PM Schaefer, H Meixner, I Prots, ...
Scientific reports 7 (1), 42942, 2017
762017
Mitochondrial matrix pH as a decisive factor in neurometabolic imaging
PM Schaefer, D Hilpert, M Niederschweiberer, L Neuhauser, S Kalinina, ...
Neurophotonics 4 (4), 045004-045004, 2017
402017
Metabolic characterization of intact cells reveals intracellular amyloid beta but not its precursor protein to reduce mitochondrial respiration
PM Schaefer, B von Einem, P Walther, E Calzia, CAF von Arnim
PloS one 11 (12), e0168157, 2016
362016
An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes
T Yardeni, AG Cristancho, AJ McCoy, PM Schaefer, MJ McManus, ...
Proceedings of the National Academy of Sciences 118 (6), e2021429118, 2021
332021
Oxygen sensing PLIM together with FLIM of intrinsic cellular fluorophores for metabolic mapping
S Kalinina, P Schaefer, J Breymayer, D Bisinger, S Chakrabortty, A Rueck
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI …, 2018
92018
Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice
PM Schaefer, J Huang, A Butic, C Perry, T Yardeni, W Tan, R Morrow, ...
Molecular Metabolism 64, 101560, 2022
82022
NADH fluorescence lifetime imaging microscopy reveals selective mitochondrial dysfunction in neurons overexpressing Alzheimer’s disease–related proteins
MA Niederschweiberer, PM Schaefer, LN Singh, L Lausser, D Bhosale, ...
Frontiers in Molecular Biosciences 8, 671274, 2021
72021
Correlated oxygen-sensing PLIM, cell metabolism FLIM and applications
AC Rück, S Kalinina, P Schaefer, B von Einem, C von Arnim
Multiphoton Microscopy in the Biomedical Sciences XVII 10069, 164-173, 2017
52017
Mitophagy-related cell death mediated by vacquinol-1 and TRPM7 blockade in glioblastoma IV
P Sander, P Walther, B Moepps, M Hinz, H Mostafa, P Schaefer, A Pala, ...
IntechOpen 5, 81-93, 2019
32019
Metabolic imaging in Alzheimer´ s Disease using NADH autofluorescence
PM Schaefer
Universität Ulm, 2018
22018
Gold nanoparticles with selective antileukemic activity in vitro and in vivo target mitochondrial respiration
AK Gaiser, S Hafner, M Schmiech, B Büchele, P Schäfer, CA von Arnim, ...
Advanced Therapeutics 2 (6), 1800149, 2019
12019
Novel mtDNA Imparts the Connective Tissue Disorder of a Tourette Pedigree
PM Schaefer, LS Alves, M Lvova, J Huang, K Rathi, K Janssen, A Butic, ...
bioRxiv, 2022.02. 25.481696, 2022
2022
Correlated simultaneous fluorescence and phosphorescence lifetime imaging for metabolic mapping and oxygen sensing in living cells
S Kalinina, P Schaefer, B von Einem, A Rück
Multiphoton Microscopy in the Biomedical Sciences XIX 10882, 316-316, 2019
2019
Mitochondrial DNA mutation causes nuclear chromatin changes and makes glutamine a substrate for histone acetylation
PK Kopinski, KA Janssen, PM Schaefer, S Trefely, CE Perry, P Potluri, ...
HUMAN GENE THERAPY 29 (12), A132-A132, 2018
2018
Inhibition of Mitochondrial Respiration by Amino‐Functionalized Gold Nanoparticles in Acute Myeloid Leukemia Cells
AK Gaiser, T Syrovets, S Hafner, M Schmiech, P Schäfer, E Calzia, ...
The FASEB Journal 32, 801.6-801.6, 2018
2018
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