Honey stimulates inflammatory cytokine production from monocytes AJ Tonks, RA Cooper, KP Jones, S Blair, J Parton, A Tonks Cytokine 21 (5), 242-247, 2003 | 679 | 2003 |
Stimulation of TNF-α release in monocytes by honey A Tonks, RA Cooper, AJ Price, PC Molan, KP Jones Cytokine 14 (4), 240-242, 2001 | 368 | 2001 |
A 5.8-kDa component of manuka honey stimulates immune cells via TLR4 AJ Tonks, E Dudley, NG Porter, J Parton, J Brazier, EL Smith, A Tonks Journal of Leucocyte Biology 82 (5), 1147-1155, 2007 | 303 | 2007 |
Do reactive oxygen species play a role in myeloid leukemias? PS Hole, RL Darley, A Tonks Blood, The Journal of the American Society of Hematology 117 (22), 5816-5826, 2011 | 288 | 2011 |
Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling PS Hole, J Zabkiewicz, C Munje, Z Newton, L Pearn, P White, N Marquez, ... Blood, The Journal of the American Society of Hematology 122 (19), 3322-3330, 2013 | 237 | 2013 |
CD200 as a prognostic factor in acute myeloid leukaemia A Tonks, R Hills, P White, B Rosie, KI Mills, AK Burnett, RL Darley Leukemia 21 (3), 566-568, 2007 | 224 | 2007 |
CD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemia SJ Coles, ECY Wang, S Man, RK Hills, AK Burnett, A Tonks, RL Darley Leukemia 25 (5), 792-799, 2011 | 186 | 2011 |
Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34+ hematopoietic progenitor cells PS Hole, L Pearn, AJ Tonks, PE James, AK Burnett, RL Darley, A Tonks Blood, The Journal of the American Society of Hematology 115 (6), 1238-1246, 2010 | 150 | 2010 |
Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia A Tonks, L Pearn, M Musson, A Gilkes, KI Mills, AK Burnett, RL Darley Leukemia 21 (12), 2495-2505, 2007 | 97 | 2007 |
The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells A Tonks, L Pearn, AJ Tonks, L Pearce, T Hoy, S Phillips, J Fisher, ... Blood, The Journal of the American Society of Hematology 101 (2), 624-632, 2003 | 78 | 2003 |
The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts J Zabkiewicz, L Pearn, RK Hills, RG Morgan, A Tonks, AK Burnett, ... Haematologica 99 (5), 858, 2014 | 71 | 2014 |
Gata2 as a crucial regulator of stem cells in adult hematopoiesis and acute myeloid leukemia JB Menendez-Gonzalez, M Vukovic, A Abdelfattah, L Saleh, A Almotiri, ... Stem cell reports 13 (2), 291-306, 2019 | 69 | 2019 |
Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3 AJ Robinson, GL Hopkins, N Rastogi, M Hodges, M Doyle, S Davies, ... Cancer Research 80 (5), 937-949, 2020 | 68 | 2020 |
Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells SJ Coles, RK Hills, ECY Wang, AK Burnett, S Man, RL Darley, A Tonks Leukemia 26 (9), 2146-2148, 2012 | 67 | 2012 |
Expression of CD200 on AML blasts directly suppresses memory T-cell function SJ Coles, RK Hills, ECY Wang, AK Burnett, S Man, RL Darley, A Tonks Leukemia 26 (9), 2148-2151, 2012 | 66 | 2012 |
γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin RG Morgan, L Pearn, K Liddiard, SL Pumford, AK Burnett, A Tonks, ... Leukemia 27 (2), 336-343, 2013 | 65 | 2013 |
Factors Affecting the Nuclear Localization of β‐Catenin in Normal and Malignant Tissue RG Morgan, J Ridsdale, A Tonks, RL Darley Journal of cellular biochemistry 115 (8), 1351-1361, 2014 | 63 | 2014 |
Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal A Tonks, AJ Tonks, L Pearn, L Pearce, T Hoy, S Couzens, J Fisher, ... Leukemia 18 (7), 1238-1245, 2004 | 56 | 2004 |
The immunosuppressive ligands PD-L1 and CD200 are linked in AML T-cell immunosuppression: identification of a new immunotherapeutic synapse SJ Coles, MN Gilmour, R Reid, S Knapper, AK Burnett, S Man, A Tonks, ... Leukemia 29 (9), 1952-1954, 2015 | 55 | 2015 |
LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells RG Morgan, J Ridsdale, M Payne, KJ Heesom, MC Wilson, A Davidson, ... Haematologica 104 (7), 1365, 2019 | 54 | 2019 |