| Elimination of Fc receptor-dependent effector functions of a modified IgG4 monoclonal antibody to human CD4 MP Reddy, CAS Kinney, MA Chaikin, A Payne, J Fishman-Lobell, P Tsui, ... The Journal of Immunology 164 (4), 1925-1933, 2000 | 390 | 2000 |
| Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys TK Hart, RM Cook, P Zia-Amirhosseini, E Minthorn, TS Sellers, BE Maleeff, ... Journal of allergy and clinical immunology 108 (2), 250-257, 2001 | 295 | 2001 |
| The role of integration host factor In gene expression in Escherichia coli M Freundlich, N Ramani, E Mathew, A Sirko, P Tsui Molecular microbiology 6 (18), 2557-2563, 1992 | 259 | 1992 |
| Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFβ1, IL-13 and CCL2 LA Murray, RL Argentieri, FX Farrell, M Bracht, H Sheng, B Whitaker, ... The international journal of biochemistry & cell biology 40 (10), 2174-2182, 2008 | 193 | 2008 |
| pH-dependent binding engineering reveals an FcRn affinity threshold that governs IgG recycling MJ Borrok, Y Wu, N Beyaz, XQ Yu, V Oganesyan, WF Dall'Acqua, P Tsui Journal of Biological Chemistry 290 (7), 4282-4290, 2015 | 130 | 2015 |
| EDG1 receptor stimulation leads to cardiac hypertrophy in rat neonatal myocytes P Robert, P Tsui, MP Laville, GP Livi, HM Sarau, A Bril, I Berrebi-Bertrand Journal of molecular and cellular cardiology 33 (9), 1589-1606, 2001 | 120 | 2001 |
| Selective targeting of TGF-β activation to treat fibroinflammatory airway disease S Minagawa, J Lou, RI Seed, A Cormier, S Wu, Y Cheng, L Murray, P Tsui, ... Science translational medicine 6 (241), 241ra79-241ra79, 2014 | 94 | 2014 |
| Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs K Freeman, P Tsui, D Moore, PC Emson, L Vawter, S Naheed, P Lane, ... Genomics 78 (3), 124-128, 2001 | 87 | 2001 |
| De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins L Shi, JC Wheeler, RW Sweet, J Lu, J Luo, M Tornetta, B Whitaker, ... Journal of molecular biology 397 (2), 385-396, 2010 | 82 | 2010 |
| The ilvB locus of Escherichia coli K-12 is an operon encoding both subunits of acetohydroxyacid synthase I P Friden, J Donegan, J Mullen, P Tsui, M Freundlich, L Eoyang, R Weber, ... Nucleic acids research 13 (11), 3979-3992, 1985 | 75 | 1985 |
| Integration host factor is a negative effector of in vivo and in vitro expression of ompC in Escherichia coli L Huang, P Tsui, M Freundlich Journal of bacteriology 172 (9), 5293-5298, 1990 | 69 | 1990 |
| Isolation of neutralizing anti-C5a monoclonal antibodies from a filamentous phage monovalent Fab display library. RS Ames, MA Tornetta, CS Jones, P Tsui Journal of immunology (Baltimore, Md.: 1950) 152 (9), 4572-4581, 1994 | 67 | 1994 |
| Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding MJ Borrok, NM Luheshi, N Beyaz, GC Davies, JW Legg, H Wu, ... MAbs 7 (4), 743-751, 2015 | 64 | 2015 |
| Characterization of the epitope for anti-human respiratory syncytial virus F protein monoclonal antibody 101F using synthetic peptides and genetic approaches SJ Wu, A Schmidt, EJ Beil, ND Day, PJ Branigan, C Liu, LL Gutshall, ... Journal of general virology 88 (10), 2719-2723, 2007 | 63 | 2007 |
| Altered osmoregulation of ompF in integration host factor mutants of Escherichia coli P Tsui, V Helu, M Freundlich Journal of bacteriology 170 (10), 4950-4953, 1988 | 63 | 1988 |
| Integration host factor binds specifically to multiple sites in the ompB promoter of Escherichia coli and inhibits transcription P Tsui, L Huang, M Freundlich Journal of bacteriology 173 (18), 5800-5807, 1991 | 62 | 1991 |
| An “Fc-silenced” IgG1 format with extended half-life designed for improved stability MJ Borrok, N Mody, X Lu, ML Kuhn, H Wu, WF Dall'Acqua, P Tsui Journal of Pharmaceutical Sciences 106 (4), 1008-1017, 2017 | 48 | 2017 |
| Isolation of a neutralizing human RSV antibody from a dominant, non-neutralizing immune repertoire by epitope-blocked panning. P Tsui, MA Tornetta, RS Ames, BC Bankosky, S Griego, C Silverman, ... Journal of immunology (Baltimore, Md.: 1950) 157 (2), 772-780, 1996 | 46 | 1996 |
| Generation, characterization and biological activity of CCL2 (MCP-1/JE) and CCL12 (MCP-5) specific antibodies P Tsui, A Das, B Whitaker, M Tornetta, N Stowell, P Kesavan, E Kaiser, ... Human antibodies 16 (3-4), 117-125, 2007 | 41 | 2007 |
| Positive and negative control of ompB transcription in Escherichia coli by cyclic AMP and the cyclic AMP receptor protein L Huang, P Tsui, M Freundlich Journal of bacteriology 174 (3), 664-670, 1992 | 41 | 1992 |
