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Dominic G. Hoch
Dominic G. Hoch
Verified email at ethz.ch
Title
Cited by
Cited by
Year
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer
MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ...
Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020
1512020
Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor
D Abegg, G Gasparini, DG Hoch, A Shuster, E Bartolami, S Matile, ...
Journal of the American Chemical Society 139 (1), 231-238, 2017
1242017
Cysteine-reactive probes and their use in chemical proteomics
DG Hoch, D Abegg, A Adibekian
Chemical Communications 54 (36), 4501-4512, 2018
722018
A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin
MG Costales, DG Hoch, D Abegg, JL Childs-Disney, SP Velagapudi, ...
Journal of the American Chemical Society 141 (7), 2960-2974, 2019
662019
Chemoproteomics‐Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT
C Wang, D Abegg, DG Hoch, A Adibekian
Angewandte Chemie International Edition 55 (8), 2911-2915, 2016
572016
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids
DC Davis, DG Hoch, L Wu, D Abegg, BS Martin, ZY Zhang, A Adibekian, ...
Journal of the American Chemical Society 140 (50), 17465-17473, 2018
452018
Divergent synthesis and identification of the cellular targets of deoxyelephantopins
R Lagoutte, C Serba, D Abegg, DG Hoch, A Adibekian, N Winssinger
Nature communications 7 (1), 1-11, 2016
442016
Total synthesis and target identification of the curcusone diterpenes
C Cui, BG Dwyer, C Liu, D Abegg, ZJ Cai, DG Hoch, X Yin, N Qiu, JQ Liu, ...
Journal of the American Chemical Society 143 (11), 4379-4386, 2021
282021
Combined omics approach identifies gambogic acid and related xanthones as covalent inhibitors of the serine palmitoyltransferase complex
DG Hoch, D Abegg, JT Hannich, D Pechalrieu, A Shuster, BG Dwyer, ...
Cell chemical biology 27 (5), 586-597. e12, 2020
232020
Chemoproteomics‐Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
BG Dwyer, C Wang, D Abegg, B Racioppo, N Qiu, Z Zhao, D Pechalrieu, ...
Angewandte Chemie International Edition 60 (6), 3071-3079, 2021
152021
Chemoproteomik‐vermittelte Entdeckung eines potenten und selektiven Inhibitors des DNA‐Reparaturproteins MGMT
C Wang, D Abegg, DG Hoch, A Adibekian
Angewandte Chemie 128 (8), 2964-2968, 2016
52016
Cysteine-specific Chemical Proteomics: From Target Identification to Drug Discovery
DG Hoch, D Abegg, C Wang, A Shuster, A Adibekian
Chimia 70 (11), 764-764, 2016
22016
Total synthesis and chemoproteomics connect curcusone diterpenes with oncogenic protein BRAT1
C Cui, BG Dwyer, C Liu, D Abegg, Z Cai, D Hoch, X Yin, N Qiu, J Liu, ...
12020
Sesquiterpenoid analogs
M Dai, DC Davis, A Adibekian, DG Hoch, ZY Zhang
US Patent 11,814,396, 2023
2023
Sesquiterpenoid analogs
M Dai, DC Davis, A Adibekian, DG Hoch, ZY Zhang
US Patent 11,518,770, 2022
2022
Chapter V. A Kinetically Attenuated Ethynylbenziodoxole Probe for Chemoproteomic Profiling Covalent Reversible and Slow-Binding Drugs
C Reversible, BG Dwyer, R Tessier, D Abegg, Z Zhao, DG Hoch, ...
Chemoproteomic Tools for Profiling Bioactive Small Molecules: From De Novo …, 2022
2022
Chapter III. Chemoproteomics-Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
BG Dwyer, C Wang, D Abegg, B Racioppo, N Qiu, Z Zhao, D Pechalrieu, ...
Chemoproteomic Tools for Profiling Bioactive Small Molecules: From De Novo …, 2022
2022
RIBOTACs–Targeted Degradation of RNA
D Trauner, KP Ruehmann
Synfacts 16 (04), 0463, 2020
2020
RIBOTACs–Targeted Degradation of RNA
MG COSTALES, H AIKAWA, Y LI, JL CHILDS-DISNEY, D ABEGG, ...
Proc. Natl. Acad. Sci. USA 117, 2406-2411, 2020
2020
Total Syntheses of Abies Sesquiterpenoids
EM Carreira, M Hönig
Synfacts 15 (02), 0120, 2019
2019
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