Choice of differentiation media significantly impacts cell lineage and response to CFTR modulators in fully differentiated primary cultures of cystic fibrosis human airway … V Saint-Criq, L Delpiano, J Casement, JC Onuora, JH Lin, MA Gray Cells 9 (9), 2137, 2020 | 39 | 2020 |
In vitro methods for the development and analysis of human primary airway epithelia A Gianotti, L Delpiano, E Caci Frontiers in pharmacology 9, 417437, 2018 | 36 | 2018 |
Small molecule anion carriers correct abnormal airway surface liquid properties in cystic fibrosis airway epithelia A Gianotti, V Capurro, L Delpiano, M Mielczarek, M García-Valverde, ... International Journal of Molecular Sciences 21 (4), 1488, 2020 | 31 | 2020 |
Esomeprazole increases airway surface liquid pH in primary cystic fibrosis epithelial cells L Delpiano, JJ Thomas, AR Yates, SJ Rice, MA Gray, V Saint-Criq Frontiers in Pharmacology 9, 413660, 2018 | 21 | 2018 |
Different reactivity of primary fibroblasts and endothelial cells towards crystalline silica: A surface radical matter M Pozzolini, L Vergani, M Ragazzoni, L Delpiano, E Grasselli, A Voci, ... Toxicology 361, 12-23, 2016 | 21 | 2016 |
The SLC26A9 inhibitor S9-A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton … S Jo, R Centeio, J Park, J Ousingsawat, D Jeon, K Talbi, R Schreiber, ... The FASEB Journal 36 (11), 2022 | 16 | 2022 |
The application of bicarbonate recovers the chemical-physical properties of airway surface liquid in cystic fibrosis epithelia models L Ferrera, V Capurro, L Delpiano, A Gianotti, O Moran Biology 10 (4), 278, 2021 | 12 | 2021 |
Drug repurposing for cystic fibrosis: Identification of drugs that induce CFTR-independent fluid secretion in nasal organoids LW Rodenburg, L Delpiano, V Railean, R Centeio, MC Pinto, SMA Smits, ... International Journal of Molecular Sciences 23 (20), 12657, 2022 | 9 | 2022 |
Inhibition of the sodium-dependent HCO3-transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype V Saint-Criq, A Guequén, AR Philp, S Villanueva, T Apablaza, ... Elife 11, e75871, 2022 | 9 | 2022 |
Development of a physiological model of human middle ear epithelium MW Mather, B Verdon, RA Botting, J Engelbert, L Delpiano, X Xu, ... Laryngoscope Investigative Otolaryngology 6 (5), 1167-1174, 2021 | 6 | 2021 |
Extracellular phosphate enhances the function of F508del-CFTR rescued by CFTR correctors V Saint-Criq, Y Wang, L Delpiano, JH Lin, DN Sheppard, MA Gray Journal of Cystic Fibrosis 20 (5), 843-850, 2021 | 5 | 2021 |
Dynamic regulation of airway surface liquid pH by TMEM16A and SLC26A4 in cystic fibrosis nasal epithelia with rare mutations L Delpiano, LW Rodenburg, M Burke, G Nelson, GD Amatngalim, ... Proceedings of the National Academy of Sciences 120 (47), e2307551120, 2023 | 1 | 2023 |
Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis. T Apablaza, M Barros-Poblete, L Delpiano, S Villanueva, A Guequen, ... bioRxiv, 2024.03. 26.586799, 2024 | | 2024 |
The Physiology of Epithelial ION and Fluid Transport: Beyond CFTR Modulators L Delpiano, MA Gray Hodson and Geddes' Cystic Fibrosis, 59-73, 2023 | | 2023 |
Alternate channel therapy for cystic fibrosis lung disease L Delpiano Newcastle University, 2023 | | 2023 |
399 Dynamic regulation of airway surface liquid pH by TMEM16A in nasal epithelia derived from cystic fibrosis donors with rare class I mutations L Delpiano, L Rodenburg, G Amatngalim, J Beekman, M Gray Journal of Cystic Fibrosis 21, S233, 2022 | | 2022 |
WS16. 05 Identification of drugs activating CFTR-independent fluid secretion in nasal organoids based on a high-content screening assay GD Amatngalim, LW Rodenburg, L Delpiano, SMA Smits, BL Aalbers, ... Journal of Cystic Fibrosis 21, S32, 2022 | | 2022 |
SLC4A4 plays a major role in airway homeostasis V Saint-Criq, A Guequén, I Fernández-Moncada, S Villanueva, ... | | 2021 |
Location, location, location: lessons from airway epithelial anion channels. L Delpiano, MA Gray Journal of Physiology 597 (24), 2019 | | 2019 |