Controlling the regional identity of hPSC-derived neurons to uncover neuronal subtype specificity of neurological disease phenotypes K Imaizumi, T Sone, K Ibata, K Fujimori, M Yuzaki, W Akamatsu, H Okano Stem cell reports 5 (6), 1010-1022, 2015 | 97 | 2015 |
Functional neurons generated from T cell-derived induced pluripotent stem cells for neurological disease modeling T Matsumoto, K Fujimori, T Andoh-Noda, T Ando, N Kuzumaki, ... Stem cell reports 6 (3), 422-435, 2016 | 65 | 2016 |
Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells K Kajikawa, K Imaizumi, M Shinozaki, S Shibata, T Shindo, T Kitagawa, ... Molecular brain 13, 1-12, 2020 | 57 | 2020 |
The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy FK Nakamoto, S Okamoto, J Mitsui, T Sone, M Ishikawa, Y Yamamoto, ... Scientific reports 8 (1), 14215, 2018 | 57 | 2018 |
Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function M Kawai, K Imaizumi, M Ishikawa, S Shibata, M Shinozaki, T Shibata, ... Cell Reports 37 (8), 2021 | 44 | 2021 |
Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury T Kitagawa, N Nagoshi, Y Kamata, M Kawai, K Ago, K Kajikawa, ... Stem cell reports 17 (1), 127-142, 2022 | 43 | 2022 |
Human astrocytes model derived from induced pluripotent stem cells N Leventoux, S Morimoto, K Imaizumi, Y Sato, S Takahashi, K Mashima, ... Cells 9 (12), 2680, 2020 | 41 | 2020 |
Non-viral induction of transgene-free iPSCs from somatic fibroblasts of multiple mammalian species S Yoshimatsu, M Nakajima, A Iguchi, T Sanosaka, T Sato, M Nakamura, ... Stem cell reports 16 (4), 754-770, 2021 | 35 | 2021 |
Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism Y Hoashi, S Okamoto, Y Abe, T Matsumoto, J Tanaka, Y Yoshida, ... Journal of Prosthodontic Research 61 (3), 242-250, 2017 | 25 | 2017 |
Single‐cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential M Lam, T Sanosaka, A Lundin, K Imaizumi, D Etal, FH Karlsson, ... Genes to Cells 24 (12), 836-847, 2019 | 23 | 2019 |
Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment X Meng, D Yao, K Imaizumi, X Chen, KW Kelley, N Reis, MV Thete, ... Nature 622 (7982), 359-366, 2023 | 16 | 2023 |
A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer H Shimada, Y Sato, T Sasaki, A Shimozawa, K Imaizumi, T Shindo, ... Cell Reports Methods 2 (9), 2022 | 15 | 2022 |
Generation of region-specific and high-purity neurons from human feeder-free iPSCs T Sato, K Imaizumi, H Watanabe, M Ishikawa, H Okano Neuroscience letters 746, 135676, 2021 | 14 | 2021 |
Modeling neurodevelopment in a dish with pluripotent stem cells K Imaizumi, H Okano Development, Growth & Differentiation 63 (1), 18-25, 2021 | 13 | 2021 |
A non-invasive system to monitor in vivo neural graft activity after spinal cord injury K Ago, N Nagoshi, K Imaizumi, T Kitagawa, M Kawai, K Kajikawa, ... Communications biology 5 (1), 803, 2022 | 12* | 2022 |
Pathogenic mutation of TDP-43 impairs RNA processing in a cell type-specific manner: implications for the pathogenesis of ALS/FTLD K Imaizumi, H Ideno, T Sato, S Morimoto, H Okano eneuro 9 (3), 2022 | 12 | 2022 |
Rostrocaudal areal patterning of human PSC-derived cortical neurons by FGF8 signaling K Imaizumi, K Fujimori, S Ishii, A Otomo, Y Hosoi, H Miyajima, H Warita, ... eneuro 5 (2), 2018 | 12 | 2018 |
Flexible and accurate substrate processing with distinct presenilin/γ-secretases in human cortical neurons H Watanabe, K Imaizumi, T Cai, Z Zhou, T Tomita, H Okano eneuro 8 (2), 2021 | 10 | 2021 |
A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition M Sho, N Ichiyanagi, K Imaizumi, M Ishikawa, S Morimoto, H Watanabe, ... Neuroscience Research 158, 47-55, 2020 | 7 | 2020 |
Gene therapy using genome‐edited iPS cells for targeting malignant glioma R Tamura, H Miyoshi, K Imaizumi, M Yo, Y Kase, T Sato, M Sato, ... Bioengineering & Translational Medicine 8 (5), e10406, 2023 | 4 | 2023 |