A comprehensive proteomics analysis reveals a secretory path-and status-dependent signature of exosomes released from tumor-associated macrophages Y Zhu, X Chen, Q Pan, Y Wang, S Su, C Jiang, Y Li, N Xu, L Wu, X Lou, ... Journal of proteome research 14 (10), 4319-4331, 2015 | 81 | 2015 |
SIRT1 activation disrupts maintenance of myelodysplastic syndrome stem and progenitor cells by restoring TET2 function J Sun, X He, Y Zhu, Z Ding, H Dong, Y Feng, J Du, H Wang, X Wu, ... Cell stem cell 23 (3), 355-369. e9, 2018 | 80 | 2018 |
PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia X He, Y Zhu, YC Lin, M Li, J Du, H Dong, J Sun, L Zhu, H Wang, Z Ding, ... Blood, The Journal of the American Society of Hematology 134 (6), 548-560, 2019 | 77 | 2019 |
Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer Q Pan, X Lou, J Zhang, Y Zhu, F Li, Q Shan, X Chen, Y Xie, S Su, H Wei, ... Scientific reports 7 (1), 25, 2017 | 50 | 2017 |
Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia Y Zhu, X He, YC Lin, H Dong, L Zhang, X Chen, Z Wang, Y Shen, M Li, ... Blood, The Journal of the American Society of Hematology 134 (15), 1257-1268, 2019 | 34 | 2019 |
Lowering endogenous cathepsin D abundance results in reactive oxygen species accumulation and cell senescence S Su, X Zhu, L Lin, X Chen, Y Wang, J Zi, Y Dong, Y Xie, Y Zhu, J Zhang, ... Molecular & Cellular Proteomics 16 (7), 1217-1232, 2017 | 19 | 2017 |
Targeting cell membrane HDM2: A novel therapeutic approach for acute myeloid leukemia H Wang, D Zhao, LX Nguyen, H Wu, L Li, D Dong, E Troadec, Y Zhu, ... Leukemia 34 (1), 75-86, 2020 | 18 | 2020 |
Protein arginine methyltransferase 1 is required for maintenance of normal adult hematopoiesis L Zhu, X He, H Dong, J Sun, H Wang, Y Zhu, F Huang, J Zou, X Zhao, L Li Blood 134, 3708, 2019 | 18 | 2019 |
Role of SIRT1 in hematologic malignancies F Huang, J Sun, L Zhang, X He, Y Zhu, H Dong, H Wang, L Zhu, J Zou, ... Journal of Zhejiang University. Science. B 20 (5), 391, 2019 | 16 | 2019 |
HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML F Huang, J Sun, W Chen, X He, Y Zhu, H Dong, H Wang, Z Li, L Zhang, ... Aging (Albany NY) 12 (17), 16759, 2020 | 15 | 2020 |
mTORC1 alters the expression of glycolytic genes by regulating KPNA2 abundances X Chen, Y Zhu, Z Wang, H Zhu, Q Pan, S Su, Y Dong, L Li, H Zhang, L Wu, ... Journal of proteomics 136, 13-24, 2016 | 13 | 2016 |
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity H Dong, X He, L Zhang, W Chen, YC Lin, SB Liu, H Wang, LXT Nguyen, ... Nature Cancer 5 (4), 601-624, 2024 | 5 | 2024 |
Nuclear phosphoproteomics analysis reveals that CDK1/2 are involved in EGF-regulated constitutive pre-mRNA splicing in MDA-MB-468 cells X Chen, D Guo, Y Zhu, F Xian, S Liu, L Wu, X Lou Journal of Proteomics 141, 77-84, 2016 | 5 | 2016 |
A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ–induced CD38 expression M Murtadha, M Park, Y Zhu, E Caserta, O Napolitano, T Tandoh, ... Blood 143 (16), 1599-1615, 2024 | 3 | 2024 |
Activation of SIRT1 deacetylase as a therapeutic approach for myelodysplastic syndromes by restoring TET2 function J Sun, Y Zhu, X He, Z Ding, D Haojie, Y Feng, X Yu, D Zhao, H Wu, ... Blood 130, 2497, 2017 | 3 | 2017 |
Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer Y Zhu, X He, S Li, Y Gan, Z Li, H Wang, H Dong, L Zhang, SL Xue, Y Xu, ... Clinical and Translational Medicine 12 (3), 2022 | 2 | 2022 |
HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation D Wu, M Li, L Zhang, J Qi, CWD Chen, X He, Y Zhu, H Dong, J Sun, L Li, ... Blood 134, 642, 2019 | 2 | 2019 |
Proteasome inhibition enhances myeloma oncolytic reovirus therapy by suppressing monocytic anti-viral immune responses AA Dona, E Caserta, M Singer, T Tandoh, L Nigam, J Winchester, ... medRxiv, 2022.03. 29.22272857, 2022 | 1 | 2022 |
Targeting PRMT9 Suppresses Acute Myeloid Leukemia Maintenance H Dong, X He, L Zhang, W Chen, Y Wu, Y Zhu, H Wang, W Huang, Y Lin, ... Blood 138, 358, 2021 | 1 | 2021 |
Repurposing Nelarabine to Induce Differentiation of Acute Myeloid Leukemia H Wang, X He, F Huang, H Dong, W Chen, Z Li, J Sun, Y Zhu, L Zhang, ... Blood 136, 26, 2020 | 1 | 2020 |