| Activation of the immune-metabolic receptor GPR84 enhances inflammation and phagocytosis in macrophages C Recio, D Lucy, GSD Purvis, P Iveson, L Zeboudj, AJ Iqbal, D Lin, ... Frontiers in immunology 9, 1419, 2018 | 115 | 2018 |
| Annexin-A1: therapeutic potential in microvascular disease GSD Purvis, E Solito, C Thiemermann Frontiers in immunology 10, 442739, 2019 | 82 | 2019 |
| Identification of AnnexinA1 as an endogenous regulator of RhoA, and its role in the pathophysiology and experimental therapy of type-2 diabetes GSD Purvis, M Collino, RA Loiola, A Baragetti, F Chiazza, M Brovelli, ... Frontiers in Immunology 10, 571, 2019 | 55 | 2019 |
| IκB kinase inhibitor attenuates sepsis-induced cardiac dysfunction in CKD J Chen, JE Kieswich, F Chiazza, AJ Moyes, T Gobbetti, GSD Purvis, ... Journal of the American Society of Nephrology 28 (1), 94-105, 2017 | 55 | 2017 |
| Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation GSD Purvis, M Collino, H Aranda‐Tavio, F Chiazza, CE O'Riordan, ... British journal of pharmacology 177 (19), 4416-4432, 2020 | 53 | 2020 |
| Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes GSD Purvis, F Chiazza, J Chen, R Azevedo-Loiola, L Martin, ... Diabetologia 61, 482-495, 2018 | 52 | 2018 |
| Bruton's tyrosine kinase inhibition attenuates the cardiac dysfunction caused by cecal ligation and puncture in mice CE O'Riordan, GSD Purvis, D Collotta, F Chiazza, B Wissuwa, S Al Zoubi, ... Frontiers in Immunology 10, 465227, 2019 | 35 | 2019 |
| Inhibition of IκB kinase at 24 hours after acute kidney injury improves recovery of renal function and attenuates fibrosis FL Johnson, NSA Patel, GSD Purvis, F Chiazza, J Chen, R Sordi, ... Journal of the American Heart Association 6 (7), e005092, 2017 | 29 | 2017 |
| RvE1 attenuates polymicrobial sepsis-induced cardiac dysfunction and enhances bacterial clearance J Chen, GSD Purvis, D Collotta, S Al Zoubi, MA Sugimoto, A Cacace, ... Frontiers in immunology 11, 2080, 2020 | 28 | 2020 |
| A biased agonist at immunometabolic receptor GPR84 causes distinct functional effects in macrophages D Lucy, GSD Purvis, L Zeboudj, M Chatzopoulou, C Recio, CJR Bataille, ... ACS Chemical Biology 14 (9), 2055-2064, 2019 | 28 | 2019 |
| X-linked immunodeficient mice with no functional Bruton's tyrosine kinase are protected from sepsis-induced multiple organ failure CE O'Riordan, GSD Purvis, D Collotta, N Krieg, B Wissuwa, MH Sheikh, ... Frontiers in immunology 11, 581758, 2020 | 24 | 2020 |
| Novel synthetic, host-defense peptide protects against organ injury/dysfunction in a rat model of severe hemorrhagic shock N Yamada, LB Martin, E Zechendorf, GSD Purvis, F Chiazza, B Varrone, ... Annals of Surgery 268 (2), 348-356, 2018 | 24 | 2018 |
| Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood-brain barrier: Therapeutic avenues MH Sheikh, M Errede, A d'Amati, NQ Khan, S Fanti, RA Loiola, S McArthur, ... Faseb Journal 36 (1), 2021 | 22 | 2021 |
| Efferocytosis perpetuates substance accumulation inside macrophage populations HZ Ford, L Zeboudj, GSD Purvis, A Ten Bokum, AE Zarebski, JA Bull, ... Proceedings of the Royal Society B 286 (1904), 20190730, 2019 | 14 | 2019 |
| Bruton's TK regulates myeloid cell recruitment during acute inflammation GSD Purvis, H Aranda‐Tavio, KM Channon, DR Greaves British Journal of Pharmacology 179 (11), 2754-2770, 2022 | 10 | 2022 |
| A synthetic peptide designed to neutralize lipopolysaccharides attenuates metaflammation and diet-induced metabolic derangements in mice S Mohammad, S Al Zoubi, D Collotta, N Krieg, B Wissuwa, ... Frontiers in Immunology 12, 701275, 2021 | 7 | 2021 |
| A human CD68 promoter-driven inducible cre-recombinase mouse line allows specific targeting of tissue resident macrophages AN Rumianek, B Davies, KM Channon, DR Greaves, GSD Purvis Frontiers in Immunology 13, 918636, 2022 | 4 | 2022 |
| Endogenous Annexin‐A1 is a Protective Determinant in HFD‐induced Insulin Resistance and Diabetic Nephropathy GSD Purvis, F Chiazza, M Collino, E Solito, C Thiemermann The FASEB Journal 31, 853.3-853.3, 2017 | 4 | 2017 |
| Inhibition of Bruton’s tyrosine kinase reduces NF-kB and NLRP3 inflammasome activity preventing insulin resistance and microvascular disease GSD Purvis, M Collino, HMA Tavio, F Chiazza, CE O’Riodan, L Zeboudj, ... bioRxiv, 745943, 2019 | 2 | 2019 |
| Ly6Chi monocytes are metabolically reprogrammed in the blood during inflammatory stimulation allowing for macrophage lineage commitment GSD Purvis, E McNeill, B Wright, S Revale, H Lockstone, KM Channon, ... bioRxiv, 2021.11. 15.468584, 2021 | 1 | 2021 |
