| Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller NT Freund, H Wang, L Scharf, L Nogueira, JA Horwitz, Y Bar-On, ... Science translational medicine 9 (373), eaal2144, 2017 | 166 | 2017 |
| Broadly neutralizing antibody 8ANC195 recognizes closed and open states of HIV-1 Env L Scharf, H Wang, H Gao, S Chen, AW McDowall, PJ Bjorkman Cell 162 (6), 1379-1390, 2015 | 164 | 2015 |
| Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop H Wang, AA Cohen, RP Galimidi, HB Gristick, GJ Jensen, PJ Bjorkman Proceedings of the National Academy of Sciences 113 (46), E7151-E7158, 2016 | 158 | 2016 |
| Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques A Escolano, HB Gristick, ME Abernathy, J Merkenschlager, R Gautam, ... Nature 570 (7762), 468-473, 2019 | 143 | 2019 |
| Partially open HIV-1 envelope structures exhibit conformational changes relevant for coreceptor binding and fusion H Wang, CO Barnes, Z Yang, MC Nussenzweig, PJ Bjorkman Cell Host & Microbe 24 (4), 579-592. e4, 2018 | 98 | 2018 |
| Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies H Wang, HB Gristick, L Scharf, AP West Jr, RP Galimidi, MS Seaman, ... Elife 6, e27389, 2017 | 59 | 2017 |
| Insights into distinct signaling profiles of the µOR activated by diverse agonists Q Qu, W Huang, D Aydin, JM Paggi, AB Seven, H Wang, S Chakraborty, ... Nature chemical biology 19 (4), 423-430, 2023 | 50 | 2023 |
| Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers AA Cohen, Z Yang, PNP Gnanapragasam, S Ou, KMA Dam, H Wang, ... PloS one 16 (3), e0247963, 2021 | 48 | 2021 |
| Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody Z Yang, H Wang, AZ Liu, HB Gristick, PJ Bjorkman Nature structural & molecular biology 26 (12), 1167-1175, 2019 | 43 | 2019 |
| Structure-based design of bitopic ligands for the µ-opioid receptor A Faouzi, H Wang, SA Zaidi, JF DiBerto, T Che, Q Qu, MJ Robertson, ... Nature 613 (7945), 767-774, 2023 | 42 | 2023 |
| A functional enrichment test for molecular convergent evolution finds a clear protein-coding signal in echolocating bats and whales A Marcovitz, Y Turakhia, HI Chen, M Gloudemans, BA Braun, H Wang, ... Proceedings of the National Academy of Sciences 116 (42), 21094-21103, 2019 | 40 | 2019 |
| Structure‐Based Evolution of G Protein‐Biased μ‐Opioid Receptor Agonists H Wang, F Hetzer, W Huang, Q Qu, J Meyerowitz, J Kaindl, H Hübner, ... Angewandte Chemie International Edition 61 (26), e202200269, 2022 | 32 | 2022 |
| Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env A Escolano, HB Gristick, R Gautam, AT DeLaitsch, ME Abernathy, Z Yang, ... Science translational medicine 13 (621), eabk1533, 2021 | 24 | 2021 |
| X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer HB Gristick, H Wang, PJ Bjorkman Acta Crystallographica Section D: Structural Biology 73 (10), 822-828, 2017 | 18 | 2017 |
| Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability A Sadaf, S Kim, HE Bae, H Wang, A Nygaard, Y Uegaki, Y Du, CF Munk, ... Acta biomaterialia 128, 393-407, 2021 | 15 | 2021 |
| Negative allosteric modulation of the glucagon receptor by RAMP2 KK Kumar, ES O’Brien, CH Habrian, NR Latorraca, H Wang, I Tuneew, ... Cell 186 (7), 1465-1477. e18, 2023 | 13 | 2023 |
| Foldable detergents for membrane protein study: Importance of detergent core flexibility in protein stabilization L Ghani, S Kim, H Wang, HS Lee, JS Mortensen, S Katsube, Y Du, ... Chemistry–A European Journal 28 (21), e202200116, 2022 | 13 | 2022 |
| New Malonate-derived tetraglucoside detergents for membrane protein stability M Ehsan, S Katsube, C Cecchetti, Y Du, JS Mortensen, H Wang, ... ACS chemical biology 15 (6), 1697-1707, 2020 | 13 | 2020 |
| Structural basis for activation of CB1 by an endocannabinoid analog K Krishna Kumar, MJ Robertson, E Thadhani, H Wang, CM Suomivuori, ... Nature Communications 14 (1), 2672, 2023 | 11 | 2023 |
| Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor J Xu, Q Wang, H Hübner, Y Hu, X Niu, H Wang, S Maeda, A Inoue, Y Tao, ... Nature Communications 14 (1), 376, 2023 | 11 | 2023 |
Pamela J BjorkmanCentennial Professor of Biology and Biological EngineeringVerified email at caltech.edu
