α9‐and α7‐containing receptors mediate the pro‐proliferative effects of nicotine in the A549 adenocarcinoma cell line V Mucchietto, F Fasoli, S Pucci, M Moretti, R Benfante, A Maroli, ... British journal of pharmacology 175 (11), 1957-1972, 2018 | 74 | 2018 |
PHOX2B-Mediated Regulation of ALK Expression: In Vitro Identification of a Functional Relationship between Two Genes Involved in Neuroblastoma T Bachetti, D Di Paolo, S Di Lascio, V Mirisola, C Brignole, M Bellotti, ... PloS one 5 (10), e13108, 2010 | 71 | 2010 |
Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structure M Busnelli, G Kleinau, M Muttenthaler, S Stoev, M Manning, L Bibic, ... Journal of medicinal chemistry 59 (15), 7152-7166, 2016 | 68 | 2016 |
Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders R Benfante, S Di Lascio, S Cardani, D Fornasari Aging clinical and experimental research 33 (4), 823-834, 2021 | 65 | 2021 |
PHOX2B regulates its own expression by a transcriptional auto-regulatory mechanism F Cargnin, A Flora, S Di Lascio, E Battaglioli, R Longhi, F Clementi, ... Journal of Biological Chemistry 280 (45), 37439-37448, 2005 | 45 | 2005 |
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer N Bancaro, B Calì, M Troiani, AR Elia, RA Arzola, G Attanasio, P Lai, ... Cancer cell 41 (3), 602-619. e11, 2023 | 41 | 2023 |
Structural and functional differences in PHOX2B frameshift mutations underlie isolated or syndromic congenital central hypoventilation syndrome S Di Lascio, R Benfante, E Di Zanni, S Cardani, A Adamo, D Fornasari, ... Human mutation 39 (2), 219-236, 2018 | 40 | 2018 |
Transcriptional dysregulation and impairment of PHOX2B auto-regulatory mechanism induced by polyalanine expansion mutations associated with congenital central hypoventilation … S Di Lascio, T Bachetti, E Saba, I Ceccherini, R Benfante, D Fornasari Neurobiology of disease 50, 187-200, 2013 | 39 | 2013 |
In vitro drug treatments reduce the deleterious effects of aggregates containing polyAla expanded PHOX2B proteins E Di Zanni, T Bachetti, S Parodi, P Bocca, I Prigione, S Di Lascio, ... Neurobiology of disease 45 (1), 508-518, 2012 | 38 | 2012 |
Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7-and α9-containing nicotinic receptors S Pucci, F Fasoli, M Moretti, R Benfante, S Di Lascio, P Viani, A Daga, ... Pharmacological research 163, 105336, 2021 | 37 | 2021 |
Transcription factor PHOX2A regulates the human α3 nicotinic receptor subunit gene promoter R Benfante, A Flora, S Di Lascio, F Cargnin, R Longhi, S Colombo, ... Journal of biological chemistry 282 (18), 13290-13302, 2007 | 37 | 2007 |
Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages: A possible link to the cholinergic anti-inflammatory pathway A Maroli, S Di Lascio, L Drufuca, S Cardani, E Setten, M Locati, ... Journal of Neuroimmunology 332, 155-166, 2019 | 36 | 2019 |
Acetyl-L-carnitine in chronic pain: A narrative review P Sarzi-Puttini, V Giorgi, S Di Lascio, D Fornasari Pharmacological Research 173, 105874, 2021 | 34 | 2021 |
Genomic characterization of de novo metastatic breast cancer AC Garrido-Castro, LF Spurr, ME Hughes, YY Li, AD Cherniack, P Kumari, ... Clinical Cancer Research 27 (4), 1105-1118, 2021 | 29 | 2021 |
Research advances on therapeutic approaches to congenital central hypoventilation syndrome (CCHS) S Di Lascio, R Benfante, S Cardani, D Fornasari Frontiers in Neuroscience 14, 615666, 2021 | 28 | 2021 |
Alanine expansions associated with congenital central hypoventilation syndrome impair PHOX2B homeodomain-mediated dimerization and nuclear import S Di Lascio, D Belperio, R Benfante, D Fornasari Journal of Biological Chemistry 291 (25), 13375-13393, 2016 | 24 | 2016 |
The E3 ubiquitin ligase TRIM11 mediates the degradation of congenital central hypoventilation syndrome-associated polyalanine-expanded PHOX2B S Parodi, E Di Zanni, S Di Lascio, P Bocca, I Prigione, D Fornasari, ... Journal of molecular medicine 90, 1025-1035, 2012 | 24 | 2012 |
The human-restricted isoform of the α7 nAChR, CHRFAM7A: a double-edged sword in neurological and inflammatory disorders S Di Lascio, D Fornasari, R Benfante International Journal of Molecular Sciences 23 (7), 3463, 2022 | 20 | 2022 |
Desogestrel down-regulates PHOX2B and its target genes in progesterone responsive neuroblastoma cells S Cardani, S Di Lascio, D Belperio, E Di Biase, I Ceccherini, R Benfante, ... Experimental Cell Research 370 (2), 671-679, 2018 | 16 | 2018 |
Identification and characterization of regulatory elements in the promoter of ACVR1, the gene mutated in Fibrodysplasia Ossificans Progressiva F Giacopelli, S Cappato, L Tonachini, M Mura, S Di Lascio, D Fornasari, ... Orphanet Journal of Rare Diseases 8, 1-16, 2013 | 13 | 2013 |