| Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus nonstructural proteins identifies unique and shared host-cell dependencies JP Davies, KM Almasy, EF McDonald, L Plate ACS infectious diseases 6 (12), 3174-3189, 2020 | 116 | 2020 |
| Benchmarking AlphaFold2 on peptide structure prediction EF McDonald, T Jones, L Plate, J Meiler, A Gulsevin Structure 31 (1), 111-119. e2, 2023 | 38 | 2023 |
| Upgraded molecular models of the human KCNQ1 potassium channel G Kuenze, AM Duran, H Woods, KR Brewer, EF McDonald, CG Vanoye, ... PloS one 14 (9), e0220415, 2019 | 25 | 2019 |
| Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants EF McDonald, CMP Sabusap, M Kim, L Plate Molecular Biology of the Cell 33 (7), ar62, 2022 | 22 | 2022 |
| Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation G Kuenze, CG Vanoye, RR Desai, S Adusumilli, KR Brewer, H Woods, ... Elife 9, e57680, 2020 | 18 | 2020 |
| Structural Comparative Modeling of Multi-Domain F508del CFTR EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler Biomolecules 12 (3), 471, 2022 | 12 | 2022 |
| Elexacaftor/VX-445–mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics M Kim, EF McDonald, CMP Sabusap, B Timalsina, D Joshi, JS Hong, ... Journal of Biological Chemistry 299 (10), 2023 | 9 | 2023 |
| General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants AG McKee, EF McDonald, WD Penn, CP Kuntz, K Noguera, ... Cell Chemical Biology 30 (6), 632-642. e5, 2023 | 8 | 2023 |
| Computational modeling and prediction of deletion mutants H Woods, DL Schiano, JI Aguirre, KV Ledwitch, EF McDonald, M Voehler, ... Structure 31 (6), 713-723. e3, 2023 | 5 | 2023 |
| Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants EF McDonald, KE Oliver, JP Schlebach, J Meiler, L Plate Plos one 19 (1), e0297560, 2024 | 3 | 2024 |
| CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine EF McDonald, J Meiler, L Plate ACS Chemical Biology 18 (10), 2128-2143, 2023 | 3 | 2023 |
| Ribosomal frameshifting selectively modulates the biosynthesis, Assembly, and function of a misfolded CFTR variant P Carmody, FJ Roushar, A Tedman, M Herwig, M Kim, EF McDonald, ... bioRxiv, 2023.05. 02.539166, 2023 | 2 | 2023 |
| Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants AG McKee, EF McDonald, WD Penn, CP Kuntz, K Noguera, ... bioRxiv, 2022.10. 14.512300, 2022 | 1 | 2022 |
| Dark nanodiscs for evaluating membrane protein thermostability by differential scanning fluorimetry JA Selvasingh, EF McDonald, PD Neufer, JR McKinney, J Meiler, ... Biophysical Journal 123 (1), 68-79, 2024 | | 2024 |
| The proteostasis interactomes of trafficking-deficient KV11. 1 variants associated with Long QT Syndrome and pharmacological chaperone rescue CL Egly, TQ Do, EF McDonald, L Barny, L Plate, B Knollmann bioRxiv, 2024.01. 31.574410, 2024 | | 2024 |
| Site-specific crosslinking reveals Phosphofructokinase-L inhibition drives self-assembly and attenuation of protein interactions A Sivadas, EF McDonald, SO Shuster, CM Davis, L Plate Advances in Biological Regulation, 100987, 2023 | | 2023 |
| Dark nanodiscs as a model membrane for evaluating membrane protein thermostability by differential scanning fluorimetry JA Selvasingh, EF McDonald, JR Mckinney, J Meiler, KV Ledwitch bioRxiv, 2023.05.08.539917, 2023 | | 2023 |
| 648 Distinct proteostasis and structural states drive VX-809 susceptibility of cystic fibrosis transmembrane conductance regulator mutants E McDonald, C Sabusap, M Kim, J Meiler, L Plate Journal of Cystic Fibrosis 21, S355-S356, 2022 | | 2022 |
| Structural Comparative Modeling of Multi-Domain F508del CFTR. Biomolecules 2022, 12, 471 EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2022 | | 2022 |
| Structural comparative modeling of multi-domain ΔF508 CFTR EF McDonald, H Woods, ST Smith, M Kim, CT Schoeder, L Plate, J Meiler bioRxiv, 2021.11. 17.468921, 2021 | | 2021 |
Lars PlateVanderbilt UniversityVerified email at vanderbilt.edu
