Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b S Hu, S Liu, Y Bian, M Poddar, S Singh, C Cao, J McGaughey, A Bell, ... Cell Reports Medicine 3 (10), 2022 | 35 | 2022 |
NOTCH-YAP1/TEAD-DNMT1 axis drives hepatocyte reprogramming into intrahepatic cholangiocarcinoma S Hu, L Molina, J Tao, S Liu, M Hassan, S Singh, M Poddar, A Bell, D Sia, ... Gastroenterology 163 (2), 449-465, 2022 | 27 | 2022 |
Wnt/β-catenin signaling and liver regeneration: circuit, biology, and opportunities S Hu, SP Monga Gene Expression 20 (3), 189, 2021 | 19 | 2021 |
Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors LM Molina, J Zhu, Q Li, T Pradhan-Sundd, Y Krutsenko, K Sayed, ... Cell reports 36 (1), 2021 | 17 | 2021 |
β-Catenin-NF-κB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction S Hu, JO Russell, S Liu, C Cao, J McGaughey, R Rai, K Kosar, J Tao, ... Elife 10, 2021 | 14 | 2021 |
Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography S Hu, S Liu, Y Bian, M Poddar, S Singh, C Cao, J McGaughey, A Bell, ... bioRxiv, 2022.03. 18.484868, 2022 | 7 | 2022 |
Hepatocyte β‐catenin loss is compensated by insulin‐mTORC1 activation to promote liver regeneration S Hu, C Cao, M Poddar, E Delgado, S Singh, A Singh‐Varma, DB Stolz, ... Hepatology 77 (5), 1593-1611, 2023 | 4 | 2023 |
Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation RM Bragg, SR Coffey, JP Cantle, S Hu, S Singh, SRW Legg, CA McHugh, ... Life Science Alliance 6 (11), 2023 | 2 | 2023 |
A Spatial Atlas of Wnt Receptors in Adult Mouse Liver J Gayden, S Hu, PN Joseph, E Delgado, S Liu, A Bell, S Puig, SP Monga, ... The American Journal of Pathology 193 (5), 558-566, 2023 | 2 | 2023 |
NOTCH-YAP1/TEAD-DNMT1 axis regulates hepatocyte reprogramming into intrahepatic cholangiocarcinoma S Hu, L Molina, J Tao, S Liu, M Hassan, S Singh, M Poddar, A Bell, D Sia, ... bioRxiv, 2020.12. 03.410993, 2020 | 2 | 2020 |
Single‐cell spatial transcriptomics analysis of a regenerating liver SP Monga, S Ko, S Hu, S Singh, M Poddar The FASEB Journal 36, 2022 | 1 | 2022 |
Elimination of Wnt secretion from hepatic stellate cells impairs hepatocyte proliferation after partial hepatectomy S Hu, S Ko, M Kim, M Preziosi, A Bell, S Monga The FASEB Journal 34 (S1), 1-1, 2020 | 1 | 2020 |
STELLATE CELL WNTS REGULATE ENDOTHELIAL CELL-HEPATOCYTE ZONATION TO BALANCE HEPATIC METABOLISM-PROLIFERATION HOMEOSTASIS A Singh-Varma, S Hu, L Min, BM Lehrich, M Poddar, I Sipula, FM Bello, ... HEPATOLOGY 78, S1531-S1531, 2023 | | 2023 |
COMPENSATORY INTERPLAY BETWEEN THE WNT-B-CATENIN AND mTORC1 PATHWAY SAFEGUARDS LIVER HOMEOSTASIS AND LIVER REGENERATION S Hu, C Cao, M Poddar, E Delgado, S Singh, AS Varma, AW Bell, ... HEPATOLOGY 76, S1260-S1260, 2022 | | 2022 |
LONG-TERM CONSEQUENCES OF LIVER REGENERATION S Ko, J Monga, Y Krutsenko, S Liu, S Hu, S Singh, M Poddar, AW Bell, ... HEPATOLOGY 76, S820-S821, 2022 | | 2022 |
A spatial atlas of Wnt and Frizzled receptor expression in adult mouse liver J Gayden, S Hu, PN Joseph, E Delgado, S Liu, A Bell, S Puig, SP Monga, ... bioRxiv, 2022.09. 23.509269, 2022 | | 2022 |
Understanding Molecular Heterogeneity in Hepatocellular Carcinoma ER Delgado, J Tao, AW Bell, S Hu, M Poddar, S Singh, SP Monga The FASEB Journal 36, 2022 | | 2022 |
Therapeutic implication of SOX9 and YAP1 co‐repression in advanced intrahepatic cholangiocarcinoma S Hu, L Molina, J Tao, S Liu, M Hassan, S Singh, M Poddar, ... The FASEB Journal 36, 2022 | | 2022 |
Hepatocyte β‐catenin is regulated by endothelial cell‐derived Wnt2 and Wnt9b to govern liver metabolic zonation and regeneration S Hu, M Poddar, S Singh, A Bell, S Monga The FASEB Journal 36, 2022 | | 2022 |
A PanFzd receptor agonist induces β‐catenin activation to promote hepatic repair after surgical and acetaminophen‐induced injury S Hu, S Singh, M Poddar, J McGaughey, L Blazer, J Adams, S Sidhu, ... The FASEB Journal 36, 2022 | | 2022 |