| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011 | 2290 | 2011 |
| Where did the linker-payload go? A quantitative investigation on the destination of the released linker-payload from an antibody-drug conjugate with a maleimide linker in plasma C Wei, G Zhang, T Clark, F Barletta, LN Tumey, B Rago, S Hansel, X Han Analytical chemistry 88 (9), 4979-4986, 2016 | 86 | 2016 |
| Hematopoietic stem cell function requires 12/15-lipoxygenase–dependent fatty acid metabolism M Kinder, C Wei, SG Shelat, M Kundu, L Zhao, IA Blair, E Puré Blood, The Journal of the American Society of Hematology 115 (24), 5012-5022, 2010 | 79 | 2010 |
| 15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation C Wei, P Zhu, SJ Shah, IA Blair Molecular pharmacology 76 (3), 516-525, 2009 | 69 | 2009 |
| 2017 White Paper on recent issues in bioanalysis: rise of hybrid LBA/LCMS immunogenicity assays (Part 2: hybrid LBA/LCMS biotherapeutics, biomarkers & immunogenicity assays and … H Neubert, A Song, A Lee, C Wei, J Duggan, K Xu, E Woolf, C Evans, ... Bioanalysis 9 (23), 1895-1912, 2017 | 32 | 2017 |
| Unconjugated payload quantification and DAR characterization of antibody–drug conjugates using high-resolution MS L Grafmuller, C Wei, R Ramanathan, F Barletta, R Steenwyk, J Tweed Bioanalysis 8 (16), 1663-1678, 2016 | 29 | 2016 |
| Quantitative conjugated payload measurement using enzymatic release of antibody–drug conjugate with cleavable linker B Rago, LN Tumey, C Wei, F Barletta, T Clark, S Hansel, X Han Bioconjugate Chemistry 28 (2), 620-626, 2017 | 26 | 2017 |
| Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects JH Toyn, KM Boy, J Raybon, JE Meredith, AS Robertson, V Guss, ... Journal of Pharmacology and Experimental Therapeutics 358 (1), 125-137, 2016 | 26 | 2016 |
| 15 (S)-Lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: evidence of lipid droplet metabolism GL Weibel, MR Joshi, C Wei, SR Bates, IA Blair, GH Rothblat Journal of lipid research 50 (12), 2371-2376, 2009 | 26 | 2009 |
| LC–MS challenges in characterizing and quantifying monoclonal antibodies (mAb) and antibody-drug conjugates (ADC) in biological samples C Wei, D Su, J Wang, W Jian, D Zhang Current Pharmacology Reports 4, 45-63, 2018 | 25 | 2018 |
| Calculated conjugated payload from immunoassay and LC–MS intact protein analysis measurements of antibody-drug conjugate B Rago, T Clark, L King, J Zhang, LN Tumey, F Li, F Barletta, C Wei, ... Bioanalysis 8 (21), 2205-2217, 2016 | 25 | 2016 |
| Utility of high-resolution accurate MS to eliminate interferences in the bioanalysis of ribavirin and its phosphate metabolites C Wei, JE Grace, TA Zvyaga, DM Drexler Bioanalysis 4 (15), 1895-1905, 2012 | 24 | 2012 |
| Identification and preclinical pharmacology of the γ‐secretase modulator BMS‐869780 JH Toyn, LA Thompson, KA Lentz, JE Meredith Jr, CR Burton, ... International Journal of Alzheimer’s Disease 2014 (1), 431858, 2014 | 16 | 2014 |
| Screening and characterization of reactive compounds with in vitro peptide-trapping and liquid chromatography/high-resolution accurate mass spectrometry C Wei, LS Chupak, T Philip, BM Johnson, R Gentles, DM Drexler Journal of biomolecular screening 19 (2), 297-307, 2014 | 13 | 2014 |
| Interferon regulatory factor-8− driven myeloid differentiation is regulated by 12/15-lipoxygenase− mediated redox signaling M Kinder, JE Thompson, C Wei, SG Shelat, IA Blair, M Carroll, E Puré Experimental hematology 38 (11), 1036-1046. e4, 2010 | 12 | 2010 |
| Intestinal excretion, intestinal recirculation, and renal tubule reabsorption are underappreciated mechanisms that drive the distribution and pharmacokinetic behavior of small … D Zhang, C Wei, CECA Hop, MR Wright, M Hu, Y Lai, SC Khojasteh, ... Journal of medicinal chemistry 64 (11), 7045-7059, 2021 | 11 | 2021 |
| Synchronous rendezvous for networks of active drifters in gyre flows C Wei, X Yu, HG Tanner, MA Hsieh Distributed Autonomous Robotic Systems: The 14th International Symposium …, 2019 | 10 | 2019 |
| 对虾白斑综合症病毒结构蛋白 VP28 的原核表达和性质研究 赵新颜， 魏聪， 戴玲芬， 高宏， 戴和平 水生生物学报 28 (3), 234-239, 2004 | 10 | 2004 |
| 2017 White Paper: rise of hybrid LBA/LCMS immunogenicity assays (Part 2: hybrid LBA/LCMS biotherapeutics, biomarkers & immunogenicity assays and regulatory agencies' inputs). H Neubert, A Song, A Lee, C Wei, J Duggan, K Xu, E Woolf, C Evans, ... Bioanalysis 9 (23), 1895-1912, 2017 | 9 | 2017 |
| A cross company perspective on the assessment of therapeutic protein biotransformation M Walles, M Berna, W Jian, S Hauri, S Hengel, L King, JC Tran, C Wei, ... Drug metabolism and disposition 50 (6), 846-857, 2022 | 8 | 2022 |
Ian A. BlairA.N. Richards Professor of Systems PharmacologyVerified email at mail.med.upenn.edu
