| An update on the role of intestinal cytochrome P450 enzymes in drug disposition F Xie, X Ding, QY Zhang Acta Pharmaceutica Sinica B 6 (5), 374-383, 2016 | 146 | 2016 |
| Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model X Zhou, X Zhuo, F Xie, K Kluetzman, YZ Shu, WG Humphreys, X Ding Journal of Pharmacology and Experimental Therapeutics 332 (2), 578-587, 2010 | 109 | 2010 |
| Olfactory mucosa: composition, enzymatic localization, and metabolism X Ding, F Xie Handbook of olfaction and gustation, 63-92, 2015 | 102 | 2015 |
| Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa L Li, Y Wei, L Van Winkle, QY Zhang, X Zhou, J Hu, F Xie, K Kluetzman, ... Journal of pharmacology and experimental therapeutics 339 (1), 62-71, 2011 | 86 | 2011 |
| Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolism C Fang, M Behr, F Xie, S Lu, M Doret, H Luo, W Yang, K Aldous, X Ding, ... Toxicology and applied pharmacology 227 (1), 48-55, 2008 | 71 | 2008 |
| The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5 F Xie, X Zhou, MB Genter, M Behr, J Gu, X Ding Drug metabolism and disposition 39 (6), 947-951, 2011 | 49 | 2011 |
| Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a … V Megaraj, X Zhou, F Xie, Z Liu, W Yang, X Ding Carcinogenesis 35 (1), 131-137, 2014 | 48 | 2014 |
| Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice X Zhou, J D'Agostino, F Xie, X Ding Journal of Pharmacology and Experimental Therapeutics 341 (1), 233-241, 2012 | 36 | 2012 |
| Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity C Fang, J Gu, F Xie, M Behr, W Yang, ED Abel, X Ding Drug metabolism and disposition 36 (8), 1722-1728, 2008 | 34 | 2008 |
| Multimodal imaging approach to examine biodistribution kinetics of Cabotegravir (GSK1265744) long acting parenteral formulation in rat BM Jucker, H Alsaid, M Rambo, SC Lenhard, B Hoang, F Xie, ... Journal of Controlled Release 268, 102-112, 2017 | 33 | 2017 |
| Mechanisms of permanent loss of olfactory receptor neurons induced by the herbicide 2, 6-dichlorobenzonitrile: effects on stem cells and noninvolvement of acute induction of … F Xie, C Fang, N Schnittke, JE Schwob, X Ding Toxicology and applied pharmacology 272 (3), 598-607, 2013 | 32 | 2013 |
| Analysis of testosterone and dihydrotestosterone in mouse tissues by liquid chromatography–electrospray ionization–tandem mass spectrometry Y Weng, F Xie, L Xu, D Zagorevski, DC Spink, X Ding Analytical biochemistry 402 (2), 121-128, 2010 | 32 | 2010 |
| A mouse model with liver-specific deletion and global suppression of the NADPH-cytochrome P450 reductase gene: characterization and utility for in vivo studies of … J Gu, CS Chen, Y Wei, C Fang, F Xie, K Kannan, W Yang, DJ Waxman, ... Journal of pharmacology and experimental therapeutics 321 (1), 9-17, 2007 | 31 | 2007 |
| Mechanisms of olfactory toxicity of the herbicide 2, 6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation F Xie, X Zhou, M Behr, C Fang, Y Horii, J Gu, K Kannan, X Ding Toxicology and applied pharmacology 249 (1), 101-106, 2010 | 29 | 2010 |
| Essential role of the cytochrome P450 enzyme CYP2A5 in olfactory mucosal toxicity of naphthalene J Hu, L Sheng, L Li, X Zhou, F Xie, J D’Agostino, Y Li, X Ding Drug metabolism and disposition 42 (1), 23-27, 2014 | 22 | 2014 |
| Effect of Cytochrome P450 Reductase Deficiency on 2-Amino-9H-pyrido[2,3-b]indole Metabolism and DNA Adduct Formation in Liver and Extrahepatic Tissues of … RJ Turesky, D Konorev, X Fan, Y Tang, L Yao, X Ding, F Xie, Y Zhu, ... Chemical research in toxicology 28 (12), 2400-2410, 2015 | 21 | 2015 |
| A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary … X Zhou, Y Wei, F Xie, CM Laukaitis, RC Karn, K Kluetzman, J Gu, ... Molecular Pharmacology 79 (4), 710-723, 2011 | 18 | 2011 |
| Metformin's intrinsic blood-to-plasma partition ratio (B/P): reconciling the perceived high in vivo B/P> 10 with the in vitro equilibrium value of unity F Xie, AB Ke, GD Bowers, MJ Zamek-Gliszczynski Journal of Pharmacology and Experimental Therapeutics 354 (2), 225-229, 2015 | 17 | 2015 |
| Bioactivation of the nasal toxicant 2, 6-dichlorobenzonitrile: an assessment of metabolic activity in human nasal mucosa and identification of indicators of exposure and … F Xie, J D’Agostino, X Zhou, X Ding Chemical research in toxicology 26 (3), 388-398, 2013 | 13 | 2013 |
| Intestinal Epithelium–Specific Knockout of the Cytochrome P450 Reductase Gene Exacerbates Dextran Sulfate Sodium–Induced Colitis Y Zhu, F Xie, L Ding, X Fan, X Ding, QY Zhang Journal of Pharmacology and Experimental Therapeutics 354 (1), 10-17, 2015 | 8 | 2015 |
