A Protein Interaction Map of Drosophila melanogaster L Giot, JS Bader, C Brouwer, A Chaudhuri, B Kuang, Y Li, YL Hao, CE Ooi, ... science 302 (5651), 1727-1736, 2003 | 2878 | 2003 |
PD-L1 immunohistochemistry assays for lung cancer: results from phase 1 of the blueprint PD-L1 IHC assay comparison project FR Hirsch, A McElhinny, D Stanforth, J Ranger-Moore, M Jansson, ... Journal of Thoracic Oncology 12 (2), 208-222, 2017 | 1281 | 2017 |
Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios JA Williams, R Hyland, BC Jones, DA Smith, S Hurst, TC Goosen, ... Drug Metabolism and Disposition 32 (11), 1201-1208, 2004 | 1094 | 2004 |
Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity. MT Makler, JM Ries, JA Williams, JE Bancroft, RC Piper, BL Gibbins, ... The American journal of tropical medicine and hygiene 48 (6), 739-741, 1993 | 1000 | 1993 |
Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7 JA Williams, BJ Ring, VE Cantrell, DR Jones, J Eckstein, K Ruterbories, ... Drug Metabolism and Disposition 30 (8), 883-891, 2002 | 582 | 2002 |
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases C Sridar, TC Goosen, UM Kent, JA Williams, PF Hollenberg Drug metabolism and disposition 32 (6), 587-594, 2004 | 290 | 2004 |
A 16-gene assay to predict recurrence after surgery in localised renal cell carcinoma: development and validation studies B Rini, A Goddard, D Knezevic, T Maddala, M Zhou, H Aydin, S Campbell, ... The lancet oncology 16 (6), 676-685, 2015 | 261 | 2015 |
In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction A Rowland, DJ Elliot, JA Williams, PI Mackenzie, RG Dickinson, ... Drug Metabolism and Disposition 34 (6), 1055-1062, 2006 | 257 | 2006 |
Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first‐and third‐generation Japanese populations: comparison with Korean, Chinese, and … SP Myrand, K Sekiguchi, MZ Man, X Lin, RY Tzeng, CH Teng, B Hee, ... Clinical Pharmacology & Therapeutics 84 (3), 347-361, 2008 | 251 | 2008 |
Mammary expression of xenobiotic metabolizing enzymes and their potential role in breast cancer JA Williams, DH Phillips Cancer research 60 (17), 4667-4677, 2000 | 220 | 2000 |
In vitro and pharmacophore insights into CYP3A enzymes S Ekins, DM Stresser, JA Williams Trends in pharmacological sciences 24 (4), 161-166, 2003 | 193 | 2003 |
Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation V Uchaipichat, LK Winner, PI Mackenzie, DJ Elliot, JA Williams, JO Miners British journal of clinical pharmacology 61 (4), 427-439, 2006 | 182 | 2006 |
Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human … JA Williams, BJ Ring, VE Cantrell, K Campanale, DR Jones, SD Hall, ... Drug Metabolism and Disposition 30 (11), 1266-1273, 2002 | 173 | 2002 |
Development of a PD-L1 complementary diagnostic immunohistochemistry assay (SP142) for atezolizumab B Vennapusa, B Baker, M Kowanetz, J Boone, I Menzl, JM Bruey, G Fine, ... Applied Immunohistochemistry & Molecular Morphology 27 (2), 92-100, 2019 | 163 | 2019 |
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial A Carrato, A Swieboda-Sadlej, M Staszewska-Skurczynska, R Lim, ... Journal of Clinical Oncology 31 (10), 1341-1347, 2013 | 150 | 2013 |
Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue JA Williams, FL Martin, GH Muir, A Hewer, PL Grover, DH Phillips Carcinogenesis 21 (9), 1683-1689, 2000 | 148 | 2000 |
Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen− Induced Hepatotoxicity AE Mutlib, TC Goosen, JN Bauman, JA Williams, S Kulkarni, S Kostrubsky Chemical research in toxicology 19 (5), 701-709, 2006 | 139 | 2006 |
In vivo activity of leflunomide: pharmacokinetic analyses and mechanism of immunosuppression ASF Chong, W Huang, W Liu, JL Luo, JK Shen, W Xu, LL Ma, L Blinder, ... Transplantation 68 (1), 100-109, 1999 | 118 | 1999 |
Current status of companion and complementary diagnostics: strategic considerations for development and launch H Scheerens, A Malong, K Bassett, Z Boyd, V Gupta, J Harris, C Mesick, ... Clinical and translational science 10 (2), 84-92, 2017 | 113 | 2017 |
Bergamottin contribution to the grapefruit juice–felodipine interaction and disposition in humans TC Goosen, D Cillié, DG Bailey, C Yu, K He, PF Hollenberg, PM Woster, ... Clinical Pharmacology & Therapeutics 76 (6), 607-617, 2004 | 110 | 2004 |