Follow
J. Andrew Williams
J. Andrew Williams
Astrazeneca
No verified email
Title
Cited by
Cited by
Year
A Protein Interaction Map of Drosophila melanogaster
L Giot, JS Bader, C Brouwer, A Chaudhuri, B Kuang, Y Li, YL Hao, CE Ooi, ...
science 302 (5651), 1727-1736, 2003
28782003
PD-L1 immunohistochemistry assays for lung cancer: results from phase 1 of the blueprint PD-L1 IHC assay comparison project
FR Hirsch, A McElhinny, D Stanforth, J Ranger-Moore, M Jansson, ...
Journal of Thoracic Oncology 12 (2), 208-222, 2017
12812017
Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios
JA Williams, R Hyland, BC Jones, DA Smith, S Hurst, TC Goosen, ...
Drug Metabolism and Disposition 32 (11), 1201-1208, 2004
10942004
Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity.
MT Makler, JM Ries, JA Williams, JE Bancroft, RC Piper, BL Gibbins, ...
The American journal of tropical medicine and hygiene 48 (6), 739-741, 1993
10001993
Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7
JA Williams, BJ Ring, VE Cantrell, DR Jones, J Eckstein, K Ruterbories, ...
Drug Metabolism and Disposition 30 (8), 883-891, 2002
5822002
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases
C Sridar, TC Goosen, UM Kent, JA Williams, PF Hollenberg
Drug metabolism and disposition 32 (6), 587-594, 2004
2902004
A 16-gene assay to predict recurrence after surgery in localised renal cell carcinoma: development and validation studies
B Rini, A Goddard, D Knezevic, T Maddala, M Zhou, H Aydin, S Campbell, ...
The lancet oncology 16 (6), 676-685, 2015
2612015
In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction
A Rowland, DJ Elliot, JA Williams, PI Mackenzie, RG Dickinson, ...
Drug Metabolism and Disposition 34 (6), 1055-1062, 2006
2572006
Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first‐and third‐generation Japanese populations: comparison with Korean, Chinese, and …
SP Myrand, K Sekiguchi, MZ Man, X Lin, RY Tzeng, CH Teng, B Hee, ...
Clinical Pharmacology & Therapeutics 84 (3), 347-361, 2008
2512008
Mammary expression of xenobiotic metabolizing enzymes and their potential role in breast cancer
JA Williams, DH Phillips
Cancer research 60 (17), 4667-4677, 2000
2202000
In vitro and pharmacophore insights into CYP3A enzymes
S Ekins, DM Stresser, JA Williams
Trends in pharmacological sciences 24 (4), 161-166, 2003
1932003
Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation
V Uchaipichat, LK Winner, PI Mackenzie, DJ Elliot, JA Williams, JO Miners
British journal of clinical pharmacology 61 (4), 427-439, 2006
1822006
Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human …
JA Williams, BJ Ring, VE Cantrell, K Campanale, DR Jones, SD Hall, ...
Drug Metabolism and Disposition 30 (11), 1266-1273, 2002
1732002
Development of a PD-L1 complementary diagnostic immunohistochemistry assay (SP142) for atezolizumab
B Vennapusa, B Baker, M Kowanetz, J Boone, I Menzl, JM Bruey, G Fine, ...
Applied Immunohistochemistry & Molecular Morphology 27 (2), 92-100, 2019
1632019
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial
A Carrato, A Swieboda-Sadlej, M Staszewska-Skurczynska, R Lim, ...
Journal of Clinical Oncology 31 (10), 1341-1347, 2013
1502013
Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue
JA Williams, FL Martin, GH Muir, A Hewer, PL Grover, DH Phillips
Carcinogenesis 21 (9), 1683-1689, 2000
1482000
Kinetics of Acetaminophen Glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential Implications in Acetaminophen− Induced Hepatotoxicity
AE Mutlib, TC Goosen, JN Bauman, JA Williams, S Kulkarni, S Kostrubsky
Chemical research in toxicology 19 (5), 701-709, 2006
1392006
In vivo activity of leflunomide: pharmacokinetic analyses and mechanism of immunosuppression
ASF Chong, W Huang, W Liu, JL Luo, JK Shen, W Xu, LL Ma, L Blinder, ...
Transplantation 68 (1), 100-109, 1999
1181999
Current status of companion and complementary diagnostics: strategic considerations for development and launch
H Scheerens, A Malong, K Bassett, Z Boyd, V Gupta, J Harris, C Mesick, ...
Clinical and translational science 10 (2), 84-92, 2017
1132017
Bergamottin contribution to the grapefruit juice–felodipine interaction and disposition in humans
TC Goosen, D Cillié, DG Bailey, C Yu, K He, PF Hollenberg, PM Woster, ...
Clinical Pharmacology & Therapeutics 76 (6), 607-617, 2004
1102004
The system can't perform the operation now. Try again later.
Articles 1–20