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Shubham Soni
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Cardiac late sodium channel current is a molecular target for the sodium/glucose cotransporter 2 inhibitor empagliflozin
K Philippaert, S Kalyaanamoorthy, M Fatehi, W Long, S Soni, NJ Byrne, ...
Circulation 143 (22), 2188-2204, 2021
1412021
Chronically elevating circulating ketones can reduce cardiac inflammation and blunt the development of heart failure
NJ Byrne, S Soni, S Takahara, M Ferdaoussi, R Al Batran, AM Darwesh, ...
Circulation: Heart Failure 13 (6), e006573, 2020
772020
Empagliflozin suppresses inflammation and protects against acute septic renal injury
ZH Maayah, M Ferdaoussi, S Takahara, S Soni, JRB Dyck
Inflammopharmacology 29 (1), 269-279, 2021
552021
Resveratrol reduces cardiac NLRP3‐inflammasome activation and systemic inflammation to lessen doxorubicin‐induced cardiotoxicity in juvenile mice
ZH Maayah, AS Alam, S Takahara, S Soni, M Ferdaoussi, N Matsumura, ...
FEBS letters 595 (12), 1681-1695, 2021
352021
Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel
W Long, M Fatehi, S Soni, R Panigrahi, K Philippaert, Y Yu, R Kelly, ...
The Journal of Physiology 598 (19), 4321-4338, 2020
292020
Ketone therapy for heart failure: current evidence for clinical use
S Takahara, S Soni, ZH Maayah, M Ferdaoussi, JRB Dyck
Cardiovascular Research 118 (4), 977-987, 2022
282022
Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue inflammation
S Takahara, M Ferdaoussi, N Srnic, ZH Maayah, S Soni, AK Migglautsch, ...
American Journal of Physiology-Heart and Circulatory Physiology 320 (1 …, 2021
222021
Exogenous ketone ester administration attenuates systemic inflammation and reduces organ damage in a lipopolysaccharide model of sepsis
S Soni, MD Martens, S Takahara, HL Silver, ZH Maayah, JR Ussher, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (11), 166507, 2022
192022
Chronic exogenous ketone supplementation blunts the decline of cardiac function in the failing heart
S Takahara, S Soni, K Phaterpekar, TT Kim, ZH Maayah, JL Levasseur, ...
ESC Heart Failure 8 (6), 5606-5612, 2021
192021
The multiple effects of SGLT2 inhibitors suggest potential benefit in COVID-19 patients
S Soni, JRB Dyck
The Canadian journal of cardiology 36 (10), 1691. e3, 2020
122020
258-LB: Vitamin D Directly Regulates TRPV1 Channel Activity and May Play an Important Role in the Autoimmune Disease of Type 1 Diabetes
W Long, M Fatehi, S Soni, R Panigrahi, RG Kelly, K Philippaert, AJ Barr, ...
Diabetes 68 (Supplement_1), 2019
42019
The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle
S Soni, SA Tabatabaei Dakhili, JR Ussher, JRB Dyck
American Journal of Physiology-Cell Physiology 326 (2), C551-C566, 2024
32024
Cannabidiol suppresses cytokine storm and protects against cardiac and renal injury associated with Sepsis
ZH Maayah, M Ferdaoussi, A Alam, S Takahara, H Silver, S Soni, ...
Cannabis and Cannabinoid Research 9 (1), 160-173, 2024
22024
Perinatal iron restriction is associated with changes in neonatal cardiac function and structure in a sex-dependent manner
RMN Noble, CD Holody, AG Woodman, C Nie, SN Liu, D Young, ...
Clinical Science 137 (15), 1115-1130, 2023
22023
Potential Benefits of Ketone Therapy as a Novel Immunometabolic Treatment for Schizophrenia
K Huizer, S Soni, MA Schmidt, N Cakici, L de Haan, JRB Dyck, ...
bioRxiv, 2024.05. 23.595523, 2024
2024
Ketone therapy reduces cardiac inflammation and cardiac dysfunction in sepsis
S Soni, M Martens, S Shoeib, Z Maayah, S Takahara, H Silver, ...
Journal of Molecular and Cellular Cardiology 173, S1-S2, 2022
2022
KETONE ESTER THERAPY REDUCES CARDIAC INFLAMMATION AND CARDIAC DYSFUNCTION IN SEPSIS
S Soni, M Martens, S Takahara, H Silver, M Ferdaoussi, J Dyck
Canadian Journal of Cardiology 38 (10), S109, 2022
2022
Ketone Therapy Reduces Systemic and Organ Inflammation in Sepsis
S Soni, M Martens, Z Maayah, S Takahara, H Silver, A Rieger, ...
The FASEB Journal 36, 2022
2022
Integrative Cardiovascular Physiology and Pathophysiology: Inhibition of ATGL in adipose tissue ameliorates isoproterenol-induced cardiac remodeling by reducing adipose tissue …
S Takahara, M Ferdaoussi, N Srnic, ZH Maayah, S Soni, AK Migglautsch, ...
American Journal of Physiology-Heart and Circulatory Physiology 320 (1), H432, 2021
2021
Vitamin D is a partial agonist of human TRPV1 channel and may play an important role in the reduction of naive T cell activation in autoimmune disease
W Long, M Fatehi, R Panigrahi, S Soni, K Philippaert, R Kelly, A Barr, ...
DIABETOLOGIA 62, S141-S141, 2019
2019
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