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Heyu Chen
Heyu Chen
AstraZeneca
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Year
LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration
M Deng, X Gui, J Kim, L Xie, W Chen, Z Li, L He, Y Chen, H Chen, W Luo, ...
Nature 562 (7728), 605-609, 2018
2032018
Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors
X Kang, J Kim, M Deng, S John, H Chen, G Wu, H Phan, CC Zhang
Cell cycle 15 (1), 25-40, 2016
1792016
A novel anti-LILRB4 CAR-T cell for the treatment of monocytic AML
S John, H Chen, M Deng, X Gui, G Wu, W Chen, Z Li, N Zhang, Z An, ...
Molecular Therapy 26 (10), 2487-2495, 2018
912018
NAD+ metabolism and NAD+-dependent enzymes: promising therapeutic targets for neurological diseases
Y Ma, H Chen, X He, H Nie, Y Hong, C Sheng, Q Wang, W Xia, W Ying
Current drug targets 13 (2), 222-229, 2012
652012
SIRT2 mediates oxidative stress-induced apoptosis of differentiated PC12 cells
H Nie, Y Hong, X Lu, J Zhang, H Chen, Y Li, Y Ma, W Ying
Neuroreport 25 (11), 838-842, 2014
592014
Nicotinamide mononucleotide improves energy activity and survival rate in an in vitro model of Parkinson's disease
LEI Lu, LE Tang, W Wei, Y Hong, H Chen, W Ying, S Chen
Experimental and Therapeutic Medicine 8 (3), 943-950, 2014
492014
SIRT2 is required for lipopolysaccharide-induced activation of BV2 microglia
H Chen, D Wu, X Ding, W Ying
Neuroreport 26 (2), 88-93, 2015
462015
Silencing of SIRT2 induces cell death and a decrease in the intracellular ATP level of PC12 cells
H Nie, H Chen, J Han, Y Hong, Y Ma, W Xia, W Ying
International journal of physiology, pathophysiology and pharmacology 3 (1), 65, 2011
462011
LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells
Z Li, M Deng, F Huang, C Jin, S Sun, H Chen, X Liu, L He, AH Sadek, ...
Cellular & molecular immunology 17 (3), 272-282, 2020
442020
Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis
C Wang, H Chen, M Zhang, J Zhang, X Wei, W Ying
Cancer letters 378 (1), 1-7, 2016
382016
NAD+/NADH metabolism and NAD+-dependent enzymes in cell death and ischemic brain injury: current advances and therapeutic implications
Y Ma, H Nie, H Chen, J Li, Y Hong, B Wang, C Wang, J Zhang, W Cao, ...
Current medicinal chemistry 22 (10), 1239-1247, 2015
372015
Identification of Centella asiatica’s effective ingredients for inducing the neuronal differentiation
H Jiang, G Zheng, J Lv, H Chen, J Lin, Y Li, G Fan, X Ding
Evidence-Based Complementary and Alternative Medicine 2016, 2016
342016
SIRT 2 mediates NADH‐induced increases in Nrf2, GCL, and glutathione by modulating Akt phosphorylation in PC 12 cells
W Cao, Y Hong, H Chen, F Wu, X Wei, W Ying
FEBS letters 590 (14), 2241-2255, 2016
332016
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
H Chen, Y Chen, M Deng, S John, X Gui, A Kansagra, W Chen, J Kim, ...
Journal for ImmunoTherapy of Cancer 8 (2), 2020
312020
CAMKs support development of acute myeloid leukemia
X Kang, C Cui, C Wang, G Wu, H Chen, Z Lu, X Chen, L Wang, J Huang, ...
Journal of hematology & oncology 11, 1-12, 2018
312018
NAD+ administration significantly attenuates synchrotron radiation X-ray-induced DNA damage and structural alterations of rodent testes
C Sheng, H Chen, B Wang, T Liu, Y Hong, J Shao, X He, Y Ma, H Nie, ...
International journal of physiology, pathophysiology and pharmacology 4 (1), 1, 2012
302012
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis
G Wu, Y Xu, RD Schultz, H Chen, J Xie, M Deng, X Liu, X Gui, S John, ...
Nature cancer 2 (11), 1170-1184, 2021
282021
Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer
M Deng, H Chen, X Liu, R Huang, Y He, B Yoo, J Xie, S John, N Zhang, ...
Antibody Therapeutics 4 (1), 16-33, 2021
282021
Oxidative stress and PARP activation mediate the NADH-induced decrease in glioma cell survival
Y Ma, H Chen, W Xia, W Ying
International journal of physiology, pathophysiology and pharmacology 3 (1), 21, 2011
232011
Malate-aspartate shuttle mediates the intracellular ATP levels, antioxidation capacity and survival of differentiated PC12 cells
C Wang, H Chen, J Zhang, Y Hong, X Ding, W Ying
International journal of physiology, pathophysiology and pharmacology 6 (2), 109, 2014
222014
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