Immunogenicity of a DNA vaccine candidate for COVID-19 TRF Smith, A Patel, S Ramos, D Elwood, X Zhu, J Yan, EN Gary, ... Nature communications 11 (1), 2601, 2020 | 654 | 2020 |
Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial P Tebas, SP Yang, JD Boyer, EL Reuschel, A Patel, A Christensen-Quick, ... EClinicalMedicine 31, 2021 | 241 | 2021 |
Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model A Patel, JN Walters, EL Reuschel, K Schultheis, E Parzych, EN Gary, ... Cell Reports Medicine 2 (10), 2021 | 82* | 2021 |
COVID-19 severity is associated with differential antibody Fc-mediated innate immune functions OS Adeniji, LB Giron, M Purwar, NF Zilberstein, AJ Kulkarni, MW Shaikh, ... MBio 12 (2), 10.1128/mbio. 00281-21, 2021 | 60 | 2021 |
SARS-CoV-2 assays to detect functional antibody responses that block ACE2 recognition in vaccinated animals and infected patients SN Walker, N Chokkalingam, EL Reuschel, M Purwar, Z Xu, EN Gary, ... Journal of Clinical Microbiology 58 (11), 10.1128/jcm. 01533-20, 2020 | 60 | 2020 |
Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: a preliminary report of a randomized, blinded, placebo-controlled, Phase 2 clinical trial in adults at … MP Mammen Jr, P Tebas, J Agnes, M Giffear, KA Kraynyak, E Blackwood, ... MedRxiv, 2021.05. 07.21256652, 2021 | 48 | 2021 |
INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants VM Andrade, A Christensen-Quick, J Agnes, J Tur, C Reed, R Kalia, ... npj Vaccines 6 (1), 121, 2021 | 43 | 2021 |
SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial The Journal of Infectious Diseases, 2022 | 39 | 2022 |
Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies S Bhattacharyya, P Singh, U Rathore, M Purwar, D Wagner, H Arendt, ... Journal of Biological Chemistry 288 (14), 9815-9825, 2013 | 30 | 2013 |
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection KM Konrath, K Liaw, Y Wu, X Zhu, SN Walker, Z Xu, K Schultheis, ... Cell reports 38 (5), 2022 | 17 | 2022 |
Bacterially expressed HIV-1 gp120 outer-domain fragment immunogens with improved stability and affinity for CD4-binding site neutralizing antibodies U Rathore, M Purwar, VS Vignesh, R Das, AA Kumar, S Bhattacharyya, ... Journal of Biological Chemistry 293 (39), 15002-15020, 2018 | 15 | 2018 |
Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates JN Walters, B Schouest, A Patel, EL Reuschel, K Schultheis, E Parzych, ... Vaccine 40 (21), 2960-2969, 2022 | 12 | 2022 |
A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens EN Gary, BM Warner, EM Parzych, BD Griffin, X Zhu, N Tailor, NJ Tursi, ... iscience 24 (7), 2021 | 12 | 2021 |
Design, display and immunogenicity of HIV1 gp120 fragment immunogens on virus-like particles M Purwar, JK Pokorski, P Singh, S Bhattacharyya, H Arendt, J DeStefano, ... Vaccine 36 (42), 6345-6353, 2018 | 12 | 2018 |
Erratum for Adeniji et al.,“COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions” OS Adeniji, LB Giron, M Purwar, NF Zilberstein, AJ Kulkarni, MW Shaikh, ... Mbio 12 (3), 10.1128/mbio. 01244-21, 2021 | 6 | 2021 |
Identification of novel neutralizing monoclonal antibodies against SARS-CoV-2 spike glycoprotein D Bordoloi, Z Xu, M Ho, M Purwar, P Bhojnagarwala, J Cassel, LB Giron, ... ACS Pharmacology & Translational Science 4 (4), 1349-1361, 2021 | 5 | 2021 |
Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer Z Xu, S Walker, MC Wise, N Chokkalingam, M Purwar, A Moore, ... Nature Communications 13 (1), 695, 2022 | 3* | 2022 |
Intradermal-delivered DNA vaccine provides anamnestic protection in a rhesus macaque SARS-CoV-2 challenge model (preprint) A Patel, J Walters, EL Reuschel, K Schultheis, E Parzych, EN Gary, ... | 2 | 2020 |
571. Safety and Immunogenicity of INO-4800, a COVID-19 DNA Vaccine as a Primary Series and Booster P Tebas, J Agnes, M Giffear, KA Kraynyak, E Blackwood, D Amante, ... Open forum infectious diseases 8 (Supplement_1), S387-S388, 2021 | 1 | 2021 |
Tethering preferences of domain families co-occurring in multi-domain proteins S Mohanty, M Purwar, N Srinivasan, N Rekha Molecular BioSystems 9 (7), 1708-1725, 2013 | 1 | 2013 |