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Yun-Chieh Sung
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Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies
YC Sung, PR Jin, LA Chu, FF Hsu, MR Wang, CC Chang, SJ Chiou, ...
Nature nanotechnology 14 (12), 1160-1169, 2019
2942019
Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer
KW Huang, FF Hsu, JT Qiu, GJ Chern, YA Lee, CC Chang, YT Huang, ...
Science advances 6 (3), eaax5032, 2020
1882020
CXCR4-targeted lipid-coated PLGA nanoparticles deliver sorafenib and overcome acquired drug resistance in liver cancer
DY Gao, TT Lin, YC Sung, YC Liu, WH Chiang, CC Chang, JY Liu, ...
Biomaterials 67, 194-203, 2015
1292015
Development and characterization of sorafenib-loaded PLGA nanoparticles for the systemic treatment of liver fibrosis
TT Lin, DY Gao, YC Liu, YC Sung, D Wan, JY Liu, T Chiang, L Wang, ...
Journal of controlled release 221, 62-70, 2016
972016
Combined delivery of sorafenib and a MEK inhibitor using CXCR4-targeted nanoparticles reduces hepatic fibrosis and prevents tumor development
YC Sung, YC Liu, PH Chao, CC Chang, PR Jin, TT Lin, JA Lin, HT Cheng, ...
Theranostics 8 (4), 894, 2018
822018
Nanoparticle Delivery of MnO2 and Antiangiogenic Therapy to Overcome Hypoxia-Driven Tumor Escape and Suppress Hepatocellular Carcinoma
CC Chang, TK Dinh, YA Lee, FN Wang, YC Sung, PL Yu, SC Chiu, ...
ACS Applied Materials & Interfaces 12 (40), 44407-44419, 2020
812020
Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors
Y Chen, YC Liu, YC Sung, RR Ramjiawan, TT Lin, CC Chang, KS Jeng, ...
Scientific reports 7 (1), 44123, 2017
702017
Galactose derivative-modified nanoparticles for efficient siRNA delivery to hepatocellular carcinoma
KW Huang, YT Lai, GJ Chern, SF Huang, CL Tsai, YC Sung, CC Chiang, ...
Biomacromolecules 19 (6), 2330-2339, 2018
672018
Multiresolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism
AYT Wu, YC Sung, YJ Chen, STY Chou, V Guo, JCY Chien, JJS Ko, ...
Advanced Science 7 (19), 2001467, 2020
592020
A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment
JS Song, CC Chang, CH Wu, TK Dinh, JJ Jan, KW Huang, MC Chou, ...
Proceedings of the National Academy of Sciences 118 (13), e2015433118, 2021
532021
A multifunctional nanocarrier for efficient TRAIL‐based gene therapy against hepatocellular carcinoma with desmoplasia in mice
CH Liu, GJ Chern, FF Hsu, KW Huang, YC Sung, HC Huang, JT Qiu, ...
Hepatology 67 (3), 899-913, 2018
432018
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles
SA Dilliard, Y Sun, MO Brown, YC Sung, S Chatterjee, L Farbiak, ...
Journal of Controlled Release 361, 361-372, 2023
242023
Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours
HC Huang, YC Sung, CP Li, D Wan, PH Chao, YT Tseng, BW Liao, ...
Gut 71 (9), 1843-1855, 2022
212022
Membrane protein modification modulates big and small extracellular vesicle biodistribution and tumorigenic potential in breast cancers in vivo
BJA Magoling, AYT Wu, YJ Chen, WWT Wong, STY Chuo, HC Huang, ...
Advanced Materials 35 (13), 2208966, 2023
182023
Delivery of sorafenib by myofibroblast-targeted nanoparticles for the treatment of renal fibrosis
HT Cheng, HC Huang, TY Lee, YH Liao, YH Sheng, PR Jin, KW Huang, ...
Journal of Controlled Release 346, 169-179, 2022
162022
An in vitro fibrotic liver lobule model through sequential cell-seeding of HSCs and HepG2 on 3D-printed poly (glycerol sebacate) acrylate scaffolds
SK Hsiao, CW Liang, TL Chang, YC Sung, YT Chen, Y Chen, J Wang
Journal of Materials Chemistry B 10 (46), 9590-9598, 2022
22022
In vivo editing of lung stem cells for durable gene correction in mice
Y Sun, S Chatterjee, X Lian, Z Traylor, SR Sattiraju, Y Xiao, SA Dilliard, ...
Science 384 (6701), 1196-1202, 2024
12024
Redirected tropisms of extracellular vesicles and exomeres yield distinct biodistribution profiles
AYT Wu, YC Sung, STY Chou, V Guo, JCY Chien, JJS Ko, AL Yang, ...
bioRxiv, 2020.03. 27.012625, 2020
12020
Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells
X Lian, S Chatterjee, Y Sun, SA Dilliard, S Moore, Y Xiao, X Bian, ...
Nature Nanotechnology, 1-9, 2024
2024
Enhancing cancer treatment Via a nanostructured chemoimmunotherapy gel facilitating interleukin-2 delivery and immunogenic cell death induction
H Yu Mu, YNN Ta, JRM Tham, FF Hsu, YC Lin, HC Huang, YC Sung, ...
Cancer Research 84 (6_Supplement), 5737-5737, 2024
2024
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