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Kimberley, C
Kimberley, C
Verified email at ucl.ac.uk
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Year
Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum‐induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer
LJ Nicholson, PR Smith, L Hiller, PW Szlosarek, C Kimberley, J Sehouli, ...
International journal of cancer 125 (6), 1454-1463, 2009
1452009
The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of …
LA Martin, S Pancholi, CMW Chan, I Farmer, C Kimberley, M Dowsett, ...
Endocrine-related cancer 12 (4), 1017-1036, 2005
1042005
FLIM FRET technology for drug discovery: Automated multiwell‐plate high‐content analysis, multiplexed readouts and application in situ
S Kumar, D Alibhai, A Margineanu, R Laine, G Kennedy, J McGinty, ...
ChemPhysChem 12 (3), 609-626, 2011
882011
Phenotypic plasticity and genetic control in colorectal cancer evolution
J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ...
Nature 611 (7937), 744-753, 2022
782022
Comparative genome sequence analysis of the Bpa/Str region in mouse and man
AM Mallon, M Platzer, R Bate, G Gloeckner, MRM Botcherby, G Nordsiek, ...
Genome research 10 (6), 758-775, 2000
652000
The co-evolution of the genome and epigenome in colorectal cancer
T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ...
Nature 611 (7937), 733-743, 2022
562022
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns
Y Bollen, E Stelloo, P van Leenen, M van den Bos, B Ponsioen, B Lu, ...
Nature genetics 53 (8), 1187-1195, 2021
402021
Genomic anatomy of the Tyrp1 (brown) deletion complex
IM Smyth, L Wilming, AW Lee, MS Taylor, P Gautier, K Barlow, J Wallis, ...
Proceedings of the National Academy of Sciences 103 (10), 3704-3709, 2006
332006
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues
C Gabbutt, RO Schenck, DJ Weisenberger, C Kimberley, A Berner, ...
Nature biotechnology 40 (5), 720-730, 2022
292022
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF
M Martins, S Warren, C Kimberley, A Margineanu, P Peschard, ...
Journal of cell science 125 (23), 5758-5769, 2012
292012
Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer
W Cross, M Mossner, S Nowinski, G Cresswell, A Banerjee, M Williams, ...
Biorxiv, 2020.03. 26.007138, 2020
152020
Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease
A Lewis, S Sánchez, G Berti, B Pan-Castillo, A Nijhuis, S Mehta, L Eleid, ...
Clinical Science 136 (19), 1405-1423, 2022
122022
Quantification of within-sample genetic heterogeneity from SNP-array data
P Martinez, C Kimberley, NJ BirkBak, A Marquard, Z Szallasi, TA Graham
Scientific Reports 7 (1), 3248, 2017
62017
FLIM-FRET of Cell Signalling in Chemotaxis
S Warren, C Kimberley, A Margineanu, R Laine, C Dunsby, M Katan, ...
Optical Molecular Probes, Imaging and Drug Delivery, MTh1C. 5, 2013
22013
FUME-TCRseq enables sensitive and accurate sequencing of the T-cell receptor from limited input of degraded RNA
AM Baker, G Nageswaran, P Nenclares, T Ronel, K Smith, C Kimberley, ...
Cancer Research, 2024
12024
FUME-TCRseq: sensitive and accurate sequencing of the T-cell receptor from limited input of degraded RNA
AM Baker, G Nageswaran, P Nenclares, T Ronel, K Smith, C Kimberley, ...
bioRxiv, 2023.04. 24.538037, 2023
12023
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma
M Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Salié, ...
Research Square, 2023
12023
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data
T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, C Kimberley, ...
bioRxiv, 2021.07. 14.451265, 2021
12021
The co-evolution of the genome and epigenome in colorectal cancer
A Sottoriva, T Heide, G Cresswell, I Spiteri, C Lynn, J Fernandez-Mateos, ...
12021
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer
E Lakatos, V Gunasri, L Zapata, J Househam, T Heide, N Trahearn, ...
bioRxiv, 2024.02. 12.579956, 2024
2024
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