CRISPR gene therapy: applications, limitations, and implications for the future F Uddin, CM Rudin, T Sen Frontiers in oncology 10, 1387, 2020 | 395 | 2020 |
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer JM Chan, A Quintanal-Villalonga, VR Gao, Y Xie, V Allaj, O Chaudhary, ... Cancer cell 39 (11), 1479-1496. e18, 2021 | 194 | 2021 |
Concurrent mutations in STK11 and KEAP1 promote ferroptosis protection and SCD1 dependence in lung cancer CA Wohlhieter, AL Richards, F Uddin, CH Hulton, À Quintanal-Villalonga, ... Cell reports 33 (9), 2020 | 143 | 2020 |
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity A Chow, S Schad, MD Green, MD Hellmann, V Allaj, N Ceglia, G Zago, ... Cancer Cell 39 (7), 973-988. e9, 2021 | 112 | 2021 |
Multiomic analysis of lung tumors defines pathways activated in neuroendocrine transformation A Quintanal-Villalonga, H Taniguchi, YA Zhan, MM Hasan, SS Chavan, ... Cancer discovery 11 (12), 3028-3047, 2021 | 80 | 2021 |
A heterometallic ruthenium–gold complex displays antiproliferative, antimigratory, and antiangiogenic properties and inhibits metastasis and angiogenesis-associated proteases … BT Elie, Y Pechenyy, F Uddin, M Contel JBIC Journal of Biological Inorganic Chemistry 23, 399-411, 2018 | 57 | 2018 |
WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC H Taniguchi, R Caeser, SS Chavan, YA Zhan, A Chow, P Manoj, F Uddin, ... Cell reports 39 (7), 2022 | 47 | 2022 |
Targeting lysine-specific demethylase 1 rescues major histocompatibility complex class I antigen presentation and overcomes programmed death-ligand 1 blockade resistance in SCLC EM Nguyen, H Taniguchi, JM Chan, YA Zhan, X Chen, J Qiu, ... Journal of Thoracic Oncology 17 (8), 1014-1031, 2022 | 40 | 2022 |
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer A Chow, FZ Uddin, M Liu, A Dobrin, BY Nabet, L Mangarin, Y Lavin, ... Immunity 56 (1), 93-106. e6, 2023 | 33 | 2023 |
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation A Quintanal-Villalonga, H Taniguchi, YA Zhan, MM Hasan, SS Chavan, ... Journal of Hematology & Oncology 14, 1-19, 2021 | 30 | 2021 |
Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade JA Pai, MD Hellmann, JL Sauter, M Mattar, H Rizvi, HJ Woo, N Shah, ... Cancer Cell 41 (4), 776-790. e7, 2023 | 26 | 2023 |
Inhibition of XPO1 sensitizes small cell lung cancer to first-and second-line chemotherapy A Quintanal-Villalonga, H Taniguchi, Y Hao, A Chow, YA Zhan, ... Cancer research 82 (3), 472-483, 2022 | 23 | 2022 |
CRISPR gene therapy: applications, limitations, and implications for the future. Front Oncol. 2020; 10: 1387 F Uddin, CM Rudin, T Sen | 15 | 2020 |
CRISPR gene therapy: applications, limitations, and implications for the future. Front Oncol 10: 1387 F Uddin, CM Rudin, T Sen | 9 | 2020 |
Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer JM Chan, Á Quintanal-Villalonga, V Gao, Y Xie, V Allaj, O Chaudhary, ... bioRxiv, 2020.12. 01.406363, 2020 | 8 | 2020 |
Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade JA Pai, A Chow, JL Sauter, M Mattar, H Rizvi, HJ Woo, N Shah, F Uddin, ... bioRxiv, 2021.09. 27.461389, 2021 | 6 | 2021 |
An optimized NGS sample preparation protocol for in vitro CRISPR screens CA Wohlhieter, F Uddin, À Quintanal-Villalonga, JT Poirier, T Sen, ... STAR Protocols 2 (2), 100390, 2021 | 4 | 2021 |
CD39 identifies tumor-reactive CD8 T cells in patients with lung cancer A Chow, FZ Uddin, L Mangarin, H Rizvi, A Dobrin, S Tischfield, ... | 2 | 2022 |
Targeting LSD1 rescues MHC class I antigen presentation and overcomes PD-L1 blockade resistance in small cell lung cancer EM Nguyen, H Taniguchi, JM Chan, YA Zhan, X Chen, J Qiu, ... Journal of thoracic oncology: official publication of the International …, 2022 | 1 | 2022 |
1800O Multi-omic characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation A Quintanal-Villalonga, H Taniguchi, YA Zhan, MM Hasan, SS Chavan, ... Annals of Oncology 32, S1226, 2021 | 1 | 2021 |